Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr16 | 87436596 | . | G | A | CCDS10960.1:NM_022818.4:c.271Gtc>Atc_NP_073729.1:p.91V>I | Homo sapiens microtubule associated protein 1 light chain 3 beta (MAP1LC3B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5gmv | 1 | Q9GZQ8 | 100.0 | 1e-89 |
X-RAY |
2017-03-08 | VAL | A:91 | B:91 | 82.0 | 0.529 | T | -68.7 | -26.6 | 82.0 | 0.529 | 0.0 |
HOH |
5.866 |
CG1 |
O |
||
VAL | C:91 | A:91 | 78.0 | 0.503 | T | -65.8 | -20.1 | NA | NA | NA | |||||||||||||
2zjd | 1 | Q9GZQ8 | 100.0 | 1e-89 |
X-RAY |
2008-06-03 | VAL | A:96 | A:91 | 79.0 | 0.51 | T | -62.5 | -21.5 | 79.0 | 0.51 | 0.0 |
HOH |
3.019 |
N |
O |
||
VAL | C:96 | C:91 | 82.0 | 0.529 | T | -65.4 | -18.1 | NA | NA | NA | |||||||||||||
5d94 | 1 | Q9GZQ8 | 100.0 | 1e-89 |
X-RAY |
2015-10-21 | VAL | A:96 | A:91 | 71.0 | 0.458 | T | -70.3 | -19.9 | 71.0 | 0.458 | 0.0 |
HOH |
3.675 |
CG1 |
O |
||
6lan | 1 | Q8IVM0,Q9GZQ8 | 99.2 | 1e-88 |
X-RAY |
2020-09-30 | VAL | A:101 | A:91 | 72.0 | 0.465 | T | -68.0 | -13.7 | 72.0 | 0.465 | 0.0 |
HOH |
2.667 |
HG22 |
O |
||
5wrd | 1 | Q9CQV6 | 95.2 | 2e-86 |
X-RAY |
2017-03-29 | VAL | A:91 | A:91 | 77.0 | 0.497 | T | -59.7 | -24.6 | 77.0 | 0.497 | 0.0 |
GOL HOH |
4.215 3.007 |
CG1 N |
C1 O |
||
VAL | B:91 | B:91 | 81.0 | 0.523 | T | -64.6 | -19.7 | NA | NA | NA | |||||||||||||
5yiq | 1 | Q9CQV6 | 95.2 | 2e-86 |
X-RAY |
2018-05-23 | VAL | A:91 | A:91 | 86.0 | 0.555 | T | -67.7 | -20.9 | 86.0 | 0.555 | 0.0 | ||||||
5yis | 1 | Q9CQV6 | 95.2 | 2e-86 |
X-RAY |
2018-05-23 | VAL | A:91 | A:91 | 80.0 | 0.516 | T | -65.7 | -23.6 | 50.0 | 0.323 | 0.193 |
D:Q01484:0.194 |
GOL |
4.023 |
CG1 |
C1 |
|
VAL | B:91 | B:91 | 82.0 | 0.529 | T | -67.1 | -16.1 | NA | NA | NA | |||||||||||||
2n9x | 1 | Q9GZQ8 | 100.0 | 3e-86 |
NMR |
2016-12-14 | VAL | A:91 | A:91 | 53.0 | 0.342 | -83.7 | 137.4 | 53.0 | 0.342 | 0.0 | |||||||
6j04 | 1 | Q9GZQ8 | 99.19 | 6e-86 |
X-RAY |
2019-11-06 | VAL | A:91 | A:91 | 81.0 | 0.523 | T | -63.5 | -20.2 | 57.0 | 0.368 | 0.155 |
C:Q9GZQ8:0.155 |
HOH |
2.922 |
N |
O |
|
VAL | B:91 | B:91 | 82.0 | 0.529 | T | -66.3 | -23.7 | NA | NA | NA | |||||||||||||
VAL | C:91 | C:91 | 75.0 | 0.484 | T | -61.0 | -29.0 | NA | NA | NA | |||||||||||||
VAL | D:91 | D:91 | 68.0 | 0.439 | T | -68.4 | -17.8 | NA | NA | NA | |||||||||||||
2z0e | 2 | Q62625 | 95.97 | 6e-86 |
X-RAY |
2007-05-22 | VAL | B:96 | B:91 | 72.0 | 0.465 | T | -85.3 | -6.9 | 15.0 | 0.097 | 0.368 |
A:Q9Y4P1:0.368 |
HOH |
5.816 |
CG1 |
O |
|
2zzp | 2 | Q62625 | 95.97 | 6e-86 |
X-RAY |
2009-03-03 | VAL | B:96 | B:91 | 55.0 | 0.355 | S | -135.2 | -180.0 | 9.0 | 0.058 | 0.297 |
A:Q9Y4P1:0.297 |
HOH |
5.985 |
N |
O |
|
5xad | 1 | Q9GZQ8 | 100.0 | 2e-85 |
X-RAY |
2017-07-12 | VAL | A:90 | A:91 | 68.0 | 0.439 | S | -106.8 | -5.3 | 68.0 | 0.439 | 0.0 |
HOH |
2.998 |
O |
O |
||
VAL | B:90 | B:91 | 67.0 | 0.432 | T | -70.0 | -1.8 | NA | NA | NA | |||||||||||||
2k6q | 1 | Q62625 | 98.33 | 3e-85 |
NMR |
2008-09-02 | VAL | A:92 | A:91 | 52.0 | 0.335 | -107.5 | 89.6 | 52.0 | 0.335 | 0.0 | |||||||
5xac | 1 | Q9GZQ8 | 100.0 | 4e-85 |
X-RAY |
2017-07-12 | VAL | A:101 | A:91 | 66.0 | 0.426 | S | -99.3 | 9.0 | 66.0 | 0.426 | 0.0 |
HOH |
3.559 |
C |
O |
||
VAL | B:101 | B:91 | 73.0 | 0.471 | T | -79.3 | -7.5 | 16.0 | 0.103 | 0.368 |
D:Q9GZQ8:0.368 |
HOH |
3.110 |
N |
O |
||||||||
VAL | C:101 | C:91 | 77.0 | 0.497 | T | -69.7 | -9.7 | 77.0 | 0.497 | 0.0 |
HOH |
2.950 |
N |
O |
|||||||||
VAL | D:101 | D:91 | 75.0 | 0.484 | T | -61.6 | -18.9 | 75.0 | 0.484 | 0.0 |
HOH |
3.687 |
CG1 |
O |
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5xae | 1 | Q9GZQ8 | 100.0 | 4e-85 |
X-RAY |
2017-07-12 | VAL | A:113 | A:89 | 120.0 | 0.774 | 360.0 | 147.1 | 120.0 | 0.774 | 0.0 |
HOH |
6.353 |
N |
O |
|||
VAL | B:113 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
VAL | C:113 | C:89 | 46.0 | 0.297 | -60.1 | -68.3 | 46.0 | 0.297 | 0.0 |
HOH |
2.264 |
N |
O |
||||||||||
VAL | D:113 | D:89 | 48.0 | 0.31 | -76.5 | -71.3 | 48.0 | 0.31 | 0.0 |
HOH |
7.323 |
CG2 |
O |
||||||||||
1ugm | 1 | Q62625 | 98.33 | 5e-85 |
X-RAY |
2004-07-06 | VAL | A:96 | A:91 | 57.0 | 0.368 | S | -92.7 | -8.0 | 57.0 | 0.368 | 0.0 |
HOH |
5.301 |
CG1 |
O |
||
2z0d | 2 | Q62625 | 98.33 | 5e-85 |
X-RAY |
2007-05-22 | VAL | B:96 | B:91 | 78.0 | 0.503 | T | -75.0 | -14.7 | 15.0 | 0.097 | 0.406 |
A:Q9Y4P1:0.406 |
HOH |
3.210 |
CG1 |
O |
|
5ms2 | 2 | Q9GZQ8 | 100.0 | 6e-85 |
X-RAY |
2017-04-19 | VAL | B:96 | B:91 | 74.0 | 0.477 | T | -90.7 | -6.7 | 24.0 | 0.155 | 0.322 |
A:Q5ZUV9:0.323 |
HOH |
5.302 |
CG2 |
O |
|
5v4k | 1 | Q9GZQ8 | 100.0 | 2e-84 |
X-RAY |
2017-05-17 | VAL | A:104 | A:1091 | 62.0 | 0.4 | S | -102.2 | -2.3 | 62.0 | 0.4 | 0.0 |
GOL HOH |
6.456 3.416 |
N N |
O3 O |
||
VAL | B:104 | B:1091 | 61.0 | 0.394 | T | -92.6 | -2.5 | 61.0 | 0.394 | 0.0 |
GOL HOH |
5.964 3.164 |
N C |
O3 O |
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3vtw | 1 | Q96CV9,Q9GZQ8 | 100.0 | 3e-84 |
X-RAY |
2013-06-26 | VAL | A:121 | A:106 | 29.0 | 0.187 | -149.8 | 122.9 | 29.0 | 0.187 | 0.0 |
HOH |
4.576 |
N |
O |
|||
VAL | B:121 | B:106 | 84.0 | 0.542 | T | -14.7 | 143.2 | NA | NA | NA | |||||||||||||
VAL | C:121 | C:106 | 46.0 | 0.297 | -107.3 | -48.3 | NA | NA | NA | ||||||||||||||
3wao | 1 | O75143,Q9GZQ8 | 100.0 | 3e-84 |
X-RAY |
2013-12-25 | VAL | A:106 | A:107 | 29.0 | 0.187 | -106.3 | 123.1 | 29.0 | 0.187 | 0.0 | |||||||
VAL | B:106 | B:107 | 54.0 | 0.348 | -114.6 | 109.8 | NA | NA | NA | ||||||||||||||
VAL | C:106 | C:107 | 55.0 | 0.355 | -129.0 | 99.6 | NA | NA | NA | ||||||||||||||
VAL | D:106 | D:107 | 80.0 | 0.516 | -82.8 | 95.8 | NA | NA | NA | ||||||||||||||
3x0w | 1 | Q9GZQ8 | 100.0 | 5e-84 |
X-RAY |
2015-01-14 | VAL | A:106 | A:118 | 55.0 | 0.355 | S | -119.4 | -0.1 | 55.0 | 0.355 | 0.0 |
HOH |
6.065 |
CG1 |
O |
||
VAL | B:106 | B:118 | 59.0 | 0.381 | S | -119.9 | 2.2 | NA | NA | NA | |||||||||||||
3vtv | 1 | Q96CV9,Q9GZQ8 | 100.0 | 5e-84 |
X-RAY |
2013-06-26 | VAL | A:106 | A:106 | 35.0 | 0.226 | -67.3 | 129.7 | 35.0 | 0.226 | 0.0 |
HOH |
2.053 |
O |
O |
|||
4waa | 1 | Q9GZQ8 | 100.0 | 6e-84 |
X-RAY |
2015-09-09 | VAL | A:106 | A:107 | 67.0 | 0.432 | -117.2 | -3.1 | 67.0 | 0.432 | 0.0 |
HOH |
3.096 |
C |
O |
|||
VAL | B:106 | B:107 | 61.0 | 0.394 | S | -102.8 | 2.7 | 61.0 | 0.394 | 0.0 |
HOH |
2.940 |
O |
O |
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5dcn | 1 | Q9GZQ8 | 100.0 | 6e-84 |
X-RAY |
2016-03-09 | VAL | A:98 | A:91 | 69.0 | 0.445 | T | -62.1 | -19.0 | 69.0 | 0.445 | 0.0 |
HOH |
4.020 |
N |
O |
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3vtu | 1 | Q9GZQ8 | 99.16 | 7e-84 |
X-RAY |
2013-06-26 | VAL | A:95 | A:95 | 43.0 | 0.277 | T | -66.3 | -46.1 | 43.0 | 0.277 | 0.0 |
HOH |
2.726 |
O |
O |
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7elg | 1 | Q9GZQ8 | 99.16 | 7e-84 |
X-RAY |
2021-10-13 | VAL | A:95 | A:95 | 50.0 | 0.323 | -122.5 | 158.7 | 50.0 | 0.323 | 0.0 |
HOH |
2.499 |
O |
O |
|||
5ms5 | 1 | Q5ZUV9,Q9GZQ8 | 100.0 | 9e-84 |
X-RAY |
2017-04-19 | VAL | A:109 | A:91 | 52.0 | 0.335 | -101.1 | -4.2 | 52.0 | 0.335 | 0.0 |
HOH |
3.143 |
N |
O |
|||
VAL | B:109 | B:91 | 47.0 | 0.303 | -101.0 | -6.2 | NA | NA | NA | ||||||||||||||
5ms6 | 1 | Q9GZQ8 | 100.0 | 9e-84 |
X-RAY |
2017-04-19 | VAL | A:109 | A:91 | 50.0 | 0.323 | -101.1 | -6.7 | 50.0 | 0.323 | 0.0 |
HOH |
3.233 |
C |
O |
|||
VAL | B:109 | B:91 | 54.0 | 0.348 | S | -99.7 | -5.5 | NA | NA | NA | |||||||||||||
2lue | 1 | Q9GZQ8 | 100.0 | 7e-82 |
NMR |
2013-07-17 | VAL | A:91 | A:91 | 78.0 | 0.503 | T | -62.0 | -20.7 | 78.0 | 0.503 | 0.0 | ||||||
5w9a | 2 | Q9GZQ8 | 100.0 | 7e-81 |
X-RAY |
2018-10-10 | VAL | B:88 | C:91 | 69.0 | 0.445 | T | -58.1 | -25.8 | 69.0 | 0.445 | 0.0 | ||||||
VAL | C:88 | D:91 | 74.0 | 0.477 | T | -59.7 | -26.9 | 74.0 | 0.477 | 0.0 | |||||||||||||
7r9w | 1 | Q9H492 | 82.5 | 3e-72 |
X-RAY |
2022-01-12 | VAL | A:93 | A:91 | 38.0 | 0.245 | -90.5 | 90.4 | 38.0 | 0.245 | 0.0 |
HOH |
6.246 |
O |
O |
|||
7r9z | 1 | Q9H492 | 82.5 | 3e-72 |
X-RAY |
2022-01-12 | VAL | A:93 | A:91 | 33.0 | 0.213 | -83.7 | 93.0 | 33.0 | 0.213 | 0.0 |
HOH |
4.097 |
CG2 |
O |
|||
7ra0 | 1 | Q9H492 | 82.5 | 3e-72 |
X-RAY |
2022-01-12 | VAL | A:93 | A:91 | 39.0 | 0.252 | -89.8 | 87.6 | 39.0 | 0.252 | 0.0 |
2JI HOH |
3.508 3.839 |
CG1 CG1 |
N11 O |
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5cx3 | 1 | Q9H492 | 82.5 | 4e-72 |
X-RAY |
2016-08-03 | VAL | A:91 | A:91 | 71.0 | 0.458 | T | -68.5 | -21.8 | 25.0 | 0.161 | 0.297 |
C:Q9H492:0.297 |
HOH |
3.633 |
N |
O |
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VAL | B:91 | B:91 | 80.0 | 0.516 | T | -65.8 | -20.2 | NA | NA | NA | |||||||||||||
VAL | C:91 | C:91 | 62.0 | 0.4 | T | -70.8 | -15.9 | 18.0 | 0.116 | 0.284 |
A:Q9H492:0.284 |
HOH |
3.484 |
CG1 |
O |
||||||||
VAL | D:91 | D:91 | 67.0 | 0.432 | T | -69.3 | -19.9 | NA | NA | NA | |||||||||||||
3eci | 1 | Q9H492 | 82.5 | 5e-72 |
X-RAY |
2008-10-14 | VAL | A:92 | A:91 | 84.0 | 0.542 | T | -71.1 | -24.7 | 84.0 | 0.542 | 0.0 | ||||||
VAL | B:92 | B:91 | 75.0 | 0.484 | S | -81.0 | -44.6 | NA | NA | NA | |||||||||||||
3wal | 1 | Q9H492 | 80.99 | 4e-71 |
X-RAY |
2013-12-25 | VAL | A:95 | A:95 | 32.0 | 0.206 | -91.2 | 103.1 | 32.0 | 0.206 | 0.0 |
HOH |
3.554 |
CG1 |
O |
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5dpr | 1 | Q9Y4G2,Q9H492 | 81.67 | 5e-71 |
X-RAY |
2016-09-28 | VAL | A:106 | A:102 | 33.0 | 0.213 | -92.4 | 120.1 | 33.0 | 0.213 | 0.0 |
HOH |
6.829 |
H |
O |
|||
VAL | B:106 | B:102 | 72.0 | 0.465 | S | -91.7 | -11.4 | NA | NA | NA | |||||||||||||
VAL | C:106 | C:102 | 78.0 | 0.503 | S | -90.9 | -21.8 | NA | NA | NA | |||||||||||||
VAL | D:106 | D:102 | 42.0 | 0.271 | -98.1 | 127.3 | NA | NA | NA | ||||||||||||||
3wan | 1 | O75143,Q9H492 | 81.67 | 5e-71 |
X-RAY |
2013-12-25 | VAL | A:106 | A:107 | 93.0 | 0.6 | S | -93.0 | -0.6 | 21.0 | 0.135 | 0.465 |
B:O75143+Q9H492:0.465 |
HOH |
2.825 |
N |
O |
|
VAL | B:106 | B:107 | 50.0 | 0.323 | -65.6 | 121.2 | 50.0 | 0.323 | 0.0 |
HOH |
2.791 |
O |
O |
||||||||||
4zdv | 1 | Q9H492 | 82.35 | 6e-71 |
X-RAY |
2015-06-03 | VAL | A:103 | A:91 | 39.0 | 0.252 | -78.0 | 121.2 | 39.0 | 0.252 | 0.0 |
HOH |
3.471 |
CA |
O |
|||
6tbe | 1 | Q9H492 | 81.9 | 1e-68 |
X-RAY |
2020-11-18 | VAL | A:91 | A:95 | 41.0 | 0.265 | -92.2 | 88.3 | 41.0 | 0.265 | 0.0 |
HOH |
3.692 |
CA |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q9gzq8-f1 | 1 | Q9GZQ8 | 100.0 | 4e-90 | VAL | A:91 | A:91 | 80.0 | 0.516 | T | -62.7 | -19.7 | |
af-a6nce7-f1 | 1 | A6NCE7 | 99.2 | 5e-89 | VAL | A:91 | A:91 | 78.0 | 0.503 | T | -64.0 | -18.2 | |
af-q9h492-f1 | 1 | Q9H492 | 82.5 | 1e-72 | VAL | A:91 | A:91 | 93.0 | 0.6 | T | -62.8 | -19.6 |