Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37863262 . G A CCDS32642.1:NM_004448.2:c.93atG>atA_NP_004439.2:p.31M>I Homo sapiens v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (ERBB2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7mn5 3 P04626,P0AEX9 99.9 0.0 EM
 2021-10-27 MET C:31 B:31 6.0 0.032 -93.5 -19.5 6.0 0.032 0.0
7mn6 2 P04626,P0AEX9 99.81 0.0 EM
 2021-10-27 MET B:31 B:31 8.0 0.043 -93.7 -25.8 8.0 0.043 0.0
7mn8 3 P04626,P0AEX9 99.81 0.0 EM
 2021-11-10 MET C:31 B:31 5.0 0.027 -106.4 -25.5 5.0 0.027 0.0
6bgt 1 P04626 100.0 0.0 X-RAY
 2018-10-31 MET A:31 C:9 8.0 0.043 -100.7 -9.4 8.0 0.043 0.0 HOH
 3.256
 CG
 O
5kwg 1 P04626 100.0 0.0 X-RAY
 2017-04-12 MET A:9 C:9 11.0 0.059 -59.5 135.2 11.0 0.059 0.0
6att 1 P04626 100.0 0.0 X-RAY
 2018-04-25 MET A:9 A:9 11.0 0.059 -94.5 -41.5 11.0 0.059 0.0
1s78 1 P04626 100.0 0.0 X-RAY
 2004-04-27 MET A:9 A:9 8.0 0.043 -123.2 -16.2 8.0 0.043 0.0
MET B:9 B:9 10.0 0.054 -122.7 -16.0 NA NA NA
3be1 1 P04626 100.0 0.0 X-RAY
 2008-11-18 MET A:9 A:9 6.0 0.032 -125.9 -13.0 6.0 0.032 0.0
3mzw 1 P04626 100.0 0.0 X-RAY
 2010-07-28 MET A:9 A:9 13.0 0.07 -115.0 -0.9 13.0 0.07 0.0
3n85 1 P04626 100.0 0.0 X-RAY
 2010-07-28 MET A:9 A:9 12.0 0.065 -134.0 -4.1 12.0 0.065 0.0 SO4
SO4
 6.309
3.086
 CE
CE
 O1
O4
5my6 1 P04626 100.0 0.0 X-RAY
 2017-08-09 MET A:8 A:31 4.0 0.022 -113.8 -17.0 4.0 0.022 0.0 HOH
 3.162
 SD
 O
6oge 1 P04626 100.0 0.0 EM
 2019-05-15 MET A:9 A:31 8.0 0.043 -141.5 53.4 8.0 0.043 0.0
6j71 1 P04626 100.0 0.0 X-RAY
 2019-02-27 MET A:10 A:31 3.0 0.016 -112.9 -11.2 3.0 0.016 0.0
1n8z 3 P04626 100.0 0.0 X-RAY
 2003-02-18 MET C:9 C:9 3.0 0.016 -97.9 -16.1 3.0 0.016 0.0 HOH
 3.595
 SD
 O
5k33 2 P04626 100.0 0.0 X-RAY
 2017-04-12 MET B:9 C:9 3.0 0.016 -97.0 11.1 3.0 0.016 0.0
5o4g 1 P04626 100.0 0.0 X-RAY
 2018-05-16 MET A:9 C:9 5.0 0.027 -94.2 -16.1 5.0 0.027 0.0
3wlw 1 P04626 100.0 0.0 X-RAY
 2015-05-27 MET A:9 A:9 9.0 0.049 -86.6 -16.7 9.0 0.049 0.0 HOH
 6.878
 CA
 O
MET B:9 B:9 4.0 0.022 -106.6 -32.3 NA NA NA
3wsq 1 P04626 100.0 0.0 X-RAY
 2015-03-25 MET A:9 A:9 3.0 0.016 -107.5 0.6 3.0 0.016 0.0
1n8y 1 22651765 85.53 0.0 X-RAY
 2003-02-18 MET A:9 C:9 3.0 0.016 -118.6 -10.4 3.0 0.016 0.0 HOH
 3.639
 SD
 O
2a91 1 P04626 99.61 0.0 X-RAY
 2005-07-26 MET A:10 A:10 3.0 0.016 -104.8 -13.0 3.0 0.016 0.0 HOH
 3.193
 CG
 O
4hrl 1 P04626 98.47 3e-130 X-RAY
 2013-10-16 MET A:9 C:9 43.0 0.232 -65.2 -21.6 43.0 0.232 0.0 HOH
 3.656
 SD
 O
4hrm 1 P04626 98.47 3e-130 X-RAY
 2013-10-16 MET A:9 C:9 57.0 NA -84.7 -12.7 57.0 NA NA
MET B:9 A:9 63.0 NA -84.5 3.1 63.0 NA NA
3h3b 1 P04626 99.48 3e-130 X-RAY
 2010-04-28 MET A:11 A:9 18.0 0.097 -82.9 -23.2 18.0 0.097 0.0 HOH
 3.578
 SD
 O
MET B:11 B:9 29.0 0.157 -81.1 -23.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04626-f1 1 P04626 100.0 0.0 MET A:31 A:31 8.0 0.043 -92.5 -25.3