Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37863291 . C A CCDS32642.1:NM_004448.2:c.122aCc>aAc_NP_004439.2:p.41T>N Homo sapiens v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (ERBB2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7mn5 3 P04626,P0AEX9 99.9 0.0 EM
 2021-10-27 THR C:41 B:41 11.0 0.079 T -110.3 -1.1 11.0 0.079 0.0
7mn6 2 P04626,P0AEX9 99.81 0.0 EM
 2021-10-27 THR B:41 B:41 10.0 0.071 G -107.8 8.2 10.0 0.071 0.0
7mn8 3 P04626,P0AEX9 99.81 0.0 EM
 2021-11-10 THR C:41 B:41 9.0 0.064 H -108.6 -2.2 9.0 0.064 0.0
6bgt 1 P04626 100.0 0.0 X-RAY
 2018-10-31 THR A:41 C:19 10.0 0.071 G -121.4 12.8 10.0 0.071 0.0 HOH
 7.107
 CA
 O
5kwg 1 P04626 100.0 0.0 X-RAY
 2017-04-12 THR A:19 C:19 7.0 0.05 H -75.6 -45.3 7.0 0.05 0.0
6att 1 P04626 100.0 0.0 X-RAY
 2018-04-25 THR A:19 A:19 9.0 0.064 H -62.1 -43.1 9.0 0.064 0.0
1s78 1 P04626 100.0 0.0 X-RAY
 2004-04-27 THR A:19 A:19 11.0 0.079 G -107.6 17.1 11.0 0.079 0.0
THR B:19 B:19 12.0 0.086 G -106.4 13.5 NA NA NA
3be1 1 P04626 100.0 0.0 X-RAY
 2008-11-18 THR A:19 A:19 12.0 0.086 H -122.4 -6.5 12.0 0.086 0.0
3mzw 1 P04626 100.0 0.0 X-RAY
 2010-07-28 THR A:19 A:19 11.0 0.079 H -118.6 -7.7 11.0 0.079 0.0 HOH
 7.075
 OG1
 O
3n85 1 P04626 100.0 0.0 X-RAY
 2010-07-28 THR A:19 A:19 14.0 0.1 G -116.1 31.3 14.0 0.1 0.0 SO4
SO4
SO4
 7.495
4.578
5.767
 CG2
O
OG1
 O1
O3
O3
5my6 1 P04626 100.0 0.0 X-RAY
 2017-08-09 THR A:18 A:41 15.0 0.107 H -121.0 0.1 15.0 0.107 0.0 HOH
 2.899
 OG1
 O
6oge 1 P04626 100.0 0.0 EM
 2019-05-15 THR A:19 A:41 34.0 0.243 T -99.0 -4.0 34.0 0.243 0.0
6j71 1 P04626 100.0 0.0 X-RAY
 2019-02-27 THR A:20 A:41 7.0 0.05 G -115.5 9.2 7.0 0.05 0.0
1n8z 3 P04626 100.0 0.0 X-RAY
 2003-02-18 THR C:19 C:19 5.0 0.036 H -75.0 -26.4 5.0 0.036 0.0 SO4
HOH
 9.078
4.445
 CG2
CB
 O1
O
5k33 2 P04626 100.0 0.0 X-RAY
 2017-04-12 THR B:19 C:19 8.0 0.057 H -67.3 -35.2 8.0 0.057 0.0
5o4g 1 P04626 100.0 0.0 X-RAY
 2018-05-16 THR A:19 C:19 8.0 0.057 T -121.4 4.4 8.0 0.057 0.0
3wlw 1 P04626 100.0 0.0 X-RAY
 2015-05-27 THR A:19 A:19 8.0 0.057 T -117.3 -15.4 8.0 0.057 0.0
THR B:19 B:19 10.0 0.071 T -108.8 -12.6 NA NA NA
3wsq 1 P04626 100.0 0.0 X-RAY
 2015-03-25 THR A:19 A:19 7.0 0.05 H -95.6 -43.2 7.0 0.05 0.0
1n8y 1 22651765 85.53 0.0 X-RAY
 2003-02-18 THR A:19 C:19 7.0 0.05 H -132.2 -18.9 7.0 0.05 0.0 HOH
 3.275
 C
 O
2a91 1 P04626 99.61 0.0 X-RAY
 2005-07-26 THR A:20 A:20 12.0 0.086 H -114.9 -8.2 12.0 0.086 0.0 HOH
 2.591
 OG1
 O
4hrl 1 P04626 98.47 3e-130 X-RAY
 2013-10-16 THR A:19 C:19 104.0 0.743 360.0 -38.9 104.0 0.743 0.0 HOH
 9.776
 O
 O
4hrm 1 P04626 98.47 3e-130 X-RAY
 2013-10-16 THR A:19 C:19 80.0 0.571 T -127.4 57.0 52.0 0.371 0.2 B:P04626:0.2
THR B:19 A:19 36.0 NA G -134.3 2.5 31.0 NA NA A:P04626:NA
3h3b 1 P04626 99.48 3e-130 X-RAY
 2010-04-28 THR A:21 A:19 81.0 0.579 H -76.1 -29.3 81.0 0.579 0.0 HOH
 8.971
 O
 O
THR B:21 B:19 86.0 0.614 H -74.5 -29.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04626-f1 1 P04626 100.0 0.0 THR A:41 A:41 13.0 0.093 H -95.4 0.8