Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37863309 . G A CCDS32642.1:NM_004448.2:c.140cGc>cAc_NP_004439.2:p.47R>H Homo sapiens v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (ERBB2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7mn5 3 P04626,P0AEX9 99.9 0.0 EM
 2021-10-27 ARG C:47 B:47 77.0 0.342 H -61.9 -45.6 77.0 0.342 0.0
7mn6 2 P04626,P0AEX9 99.81 0.0 EM
 2021-10-27 ARG B:47 B:47 99.0 0.44 H -58.4 -49.1 99.0 0.44 0.0
7mn8 3 P04626,P0AEX9 99.81 0.0 EM
 2021-11-10 ARG C:47 B:47 67.0 0.298 H -64.3 -46.7 67.0 0.298 0.0
6bgt 1 P04626 100.0 0.0 X-RAY
 2018-10-31 ARG A:47 C:25 85.0 0.378 H -58.7 -51.0 85.0 0.378 0.0 HOH
 2.179
 NH1
 O
5kwg 1 P04626 100.0 0.0 X-RAY
 2017-04-12 ARG A:25 C:25 105.0 0.467 H -57.8 -32.2 105.0 0.467 0.0
6att 1 P04626 100.0 0.0 X-RAY
 2018-04-25 ARG A:25 A:25 89.0 0.396 H -64.2 -58.0 89.0 0.396 0.0
1s78 1 P04626 100.0 0.0 X-RAY
 2004-04-27 ARG A:25 A:25 100.0 0.444 H -56.8 -55.3 100.0 0.444 0.0
ARG B:25 B:25 98.0 0.436 H -54.5 -57.9 NA NA NA
3be1 1 P04626 100.0 0.0 X-RAY
 2008-11-18 ARG A:25 A:25 76.0 0.338 H -56.9 -42.0 76.0 0.338 0.0
3mzw 1 P04626 100.0 0.0 X-RAY
 2010-07-28 ARG A:25 A:25 99.0 0.44 H -59.5 -49.7 99.0 0.44 0.0
3n85 1 P04626 100.0 0.0 X-RAY
 2010-07-28 ARG A:25 A:25 84.0 0.373 H -57.8 -53.2 84.0 0.373 0.0 SO4
 9.228
 N
 O3
5my6 1 P04626 100.0 0.0 X-RAY
 2017-08-09 ARG A:24 A:47 89.0 0.396 H -59.8 -48.5 89.0 0.396 0.0 HOH
 3.510
 NH1
 O
6oge 1 P04626 100.0 0.0 EM
 2019-05-15 ARG A:25 A:47 104.0 0.462 H -68.9 -34.4 104.0 0.462 0.0
6j71 1 P04626 100.0 0.0 X-RAY
 2019-02-27 ARG A:26 A:47 77.0 0.342 H -61.7 -47.5 77.0 0.342 0.0
1n8z 3 P04626 100.0 0.0 X-RAY
 2003-02-18 ARG C:25 C:25 95.0 0.422 H -67.9 -53.2 95.0 0.422 0.0 HOH
 8.908
 N
 O
5k33 2 P04626 100.0 0.0 X-RAY
 2017-04-12 ARG B:25 C:25 100.0 0.444 H -59.2 -60.5 100.0 0.444 0.0
5o4g 1 P04626 100.0 0.0 X-RAY
 2018-05-16 ARG A:25 C:25 83.0 0.369 H -71.3 -29.8 83.0 0.369 0.0
3wlw 1 P04626 100.0 0.0 X-RAY
 2015-05-27 ARG A:25 A:25 90.0 0.4 H -61.6 -40.6 90.0 0.4 0.0
ARG B:25 B:25 89.0 0.396 H -60.7 -46.8 NA NA NA
3wsq 1 P04626 100.0 0.0 X-RAY
 2015-03-25 ARG A:25 A:25 85.0 0.378 H -62.7 -9.5 85.0 0.378 0.0
1n8y 1 22651765 85.53 0.0 X-RAY
 2003-02-18 ARG A:25 C:25 87.0 0.387 H -59.0 -50.3 87.0 0.387 0.0 HOH
 7.578
 NH1
 O
2a91 1 P04626 99.61 0.0 X-RAY
 2005-07-26 ARG A:26 A:26 74.0 0.329 H -54.3 -49.5 74.0 0.329 0.0 NAG
HOH
 9.126
5.515
 NH2
O
 C8
O
4hrl 1 P04626 98.47 3e-130 X-RAY
 2013-10-16 ARG A:25 C:25 77.0 0.342 H -63.2 -53.6 77.0 0.342 0.0 HOH
 3.251
 NH2
 O
4hrm 1 P04626 98.47 3e-130 X-RAY
 2013-10-16 ARG A:25 C:25 101.0 0.449 H -61.1 -62.7 101.0 0.449 0.0
ARG B:25 A:25 24.0 NA H -54.4 -63.9 24.0 NA NA
3h3b 1 P04626 99.48 3e-130 X-RAY
 2010-04-28 ARG A:27 A:25 71.0 0.316 H -62.9 -46.0 71.0 0.316 0.0 HOH
 7.258
 O
 O
ARG B:27 B:25 94.0 0.418 H -63.9 -47.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04626-f1 1 P04626 100.0 0.0 ARG A:47 A:47 90.0 0.4 H -65.8 -53.2