Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37864646 . C A CCDS32642.1:NM_004448.2:c.298Cgg>Agg_NP_004439.2:p.100R>R Homo sapiens v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (ERBB2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7mn5 3 P04626,P0AEX9 99.9 0.0 EM
 2021-10-27 ARG C:100 B:100 74.0 0.329 -99.5 -43.7 74.0 0.329 0.0 NAG
NAG
BMA
MAN
 5.680
6.895
9.625
8.831
 NH1
NH2
NH2
NH2
 O3
C6
C2
O5
7mn6 2 P04626,P0AEX9 99.81 0.0 EM
 2021-10-27 ARG B:100 B:100 73.0 0.324 -99.3 -43.7 73.0 0.324 0.0 NAG
NAG
BMA
 5.469
4.723
8.433
 NH1
NH1
NH2
 O3
O6
C1
7mn8 3 P04626,P0AEX9 99.81 0.0 EM
 2021-11-10 ARG C:100 B:100 67.0 0.298 -104.8 -41.6 67.0 0.298 0.0 NAG
NAG
BMA
MAN
 6.245
5.337
9.513
9.209
 NH1
NH1
NH2
NH2
 O7
O6
C1
O5
6bgt 1 P04626 100.0 0.0 X-RAY
 2018-10-31 ARG A:100 C:78 56.0 0.249 -99.7 -35.6 56.0 0.249 0.0 NAG
HOH
 8.427
5.097
 CG
N
 C8
O
5kwg 1 P04626 100.0 0.0 X-RAY
 2017-04-12 ARG A:78 C:78 65.0 0.289 -138.2 9.6 65.0 0.289 0.0
6att 1 P04626 100.0 0.0 X-RAY
 2018-04-25 ARG A:78 A:78 65.0 0.289 -104.7 -21.5 65.0 0.289 0.0 NAG
NAG
 6.336
7.296
 NH2
NH2
 O3
C6
1s78 1 P04626 100.0 0.0 X-RAY
 2004-04-27 ARG A:78 A:78 51.0 0.227 -109.1 -47.6 51.0 0.227 0.0 NAG
 8.704
 CG
 C8
ARG B:78 B:78 53.0 0.236 -109.1 -48.3 NA NA NA
3be1 1 P04626 100.0 0.0 X-RAY
 2008-11-18 ARG A:78 A:78 82.0 0.364 -88.1 -30.5 82.0 0.364 0.0 NAG
 5.817
 NH1
 C8
3mzw 1 P04626 100.0 0.0 X-RAY
 2010-07-28 ARG A:78 A:78 41.0 0.182 -105.0 -41.3 41.0 0.182 0.0 NAG
NAG
 7.677
9.948
 CG
CB
 C8
O6
3n85 1 P04626 100.0 0.0 X-RAY
 2010-07-28 ARG A:78 A:78 77.0 0.342 -99.6 -34.2 77.0 0.342 0.0 NAG
NAG
 5.420
7.111
 NH1
NH1
 O7
O6
5my6 1 P04626 100.0 0.0 X-RAY
 2017-08-09 ARG A:77 A:100 78.0 0.347 -99.9 -32.1 78.0 0.347 0.0 NAG
NAG
HOH
 5.878
5.524
2.690
 NH1
NH2
NE
 O7
O6
O
6oge 1 P04626 100.0 0.0 EM
 2019-05-15 ARG A:78 A:100 48.0 0.213 -77.5 -50.5 48.0 0.213 0.0 NAG
NAG
 7.914
9.302
 CG
CG
 O7
C6
6j71 1 P04626 100.0 0.0 X-RAY
 2019-02-27 ARG A:79 A:100 54.0 0.24 -101.5 -45.9 54.0 0.24 0.0 NAG
 8.623
 CD
 O7
1n8z 3 P04626 100.0 0.0 X-RAY
 2003-02-18 ARG C:78 C:78 44.0 0.196 -98.3 -40.7 44.0 0.196 0.0 NAG
HOH
 7.980
7.760
 CG
CG
 O7
O
5k33 2 P04626 100.0 0.0 X-RAY
 2017-04-12 ARG B:78 C:78 76.0 0.338 -99.8 -41.0 76.0 0.338 0.0 NAG
NAG
 5.306
4.721
 HH12
HH12
 HO3
H83
5o4g 1 P04626 100.0 0.0 X-RAY
 2018-05-16 ARG A:78 C:78 47.0 0.209 -91.9 -37.6 47.0 0.209 0.0 NAG
 8.066
 CG
 C8
3wlw 1 P04626 100.0 0.0 X-RAY
 2015-05-27 ARG A:78 A:78 42.0 0.187 -132.7 -40.8 42.0 0.187 0.0 NAG
HOH
 8.561
7.772
 CG
NH2
 C8
O
ARG B:78 B:78 45.0 0.2 -113.1 -34.6 NA NA NA
3wsq 1 P04626 100.0 0.0 X-RAY
 2015-03-25 ARG A:78 A:78 50.0 0.222 -60.4 -84.4 50.0 0.222 0.0
1n8y 1 22651765 85.53 0.0 X-RAY
 2003-02-18 ARG A:78 C:78 66.0 0.293 -103.8 -33.4 66.0 0.293 0.0 NAG
NAG
HOH
 5.990
8.148
3.207
 NH1
NH2
CZ
 O7
O6
O
2a91 1 P04626 99.61 0.0 X-RAY
 2005-07-26 ARG A:79 A:79 50.0 0.222 -92.7 -39.6 50.0 0.222 0.0 NAG
HOH
 8.392
3.521
 CG
NH1
 C8
O
4hrl 1 P04626 98.47 3e-130 X-RAY
 2013-10-16 ARG A:78 C:78 36.0 NA -83.7 -34.7 36.0 NA NA HOH
 6.917
 N
 O
4hrm 1 P04626 98.47 3e-130 X-RAY
 2013-10-16 ARG A:78 C:78 35.0 NA -90.0 -44.2 35.0 NA NA
ARG B:78 A:78 41.0 NA -116.8 -31.0 41.0 NA NA
3h3b 1 P04626 99.48 3e-130 X-RAY
 2010-04-28 ARG A:80 A:78 114.0 0.507 -98.3 -37.0 114.0 0.507 0.0 HOH
 4.376
 CB
 O
ARG B:80 B:78 84.0 0.373 -107.6 -35.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04626-f1 1 P04626 100.0 0.0 ARG A:100 A:100 65.0 0.289 -98.0 -40.9