Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37864781 . C A CCDS32642.1:NM_004448.2:c.433Ctc>Atc_NP_004439.2:p.145L>I Homo sapiens v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (ERBB2), transcript variant 1, mRNA.
pdb_id: 
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label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7mn5 3 P04626,P0AEX9 99.9 0.0 EM
 2021-10-27 LEU C:145 B:145 5.0 0.029 -76.2 114.9 5.0 0.029 0.0
7mn6 2 P04626,P0AEX9 99.81 0.0 EM
 2021-10-27 LEU B:145 B:145 3.0 0.018 -76.7 115.3 3.0 0.018 0.0
7mn8 3 P04626,P0AEX9 99.81 0.0 EM
 2021-11-10 LEU C:145 B:145 3.0 0.018 -75.7 110.8 3.0 0.018 0.0
6bgt 1 P04626 100.0 0.0 X-RAY
 2018-10-31 LEU A:145 C:123 4.0 0.024 -74.2 99.9 4.0 0.024 0.0 HOH
 3.426
 N
 O
5kwg 1 P04626 100.0 0.0 X-RAY
 2017-04-12 LEU A:123 C:123 15.0 0.088 -74.6 130.2 15.0 0.088 0.0
6att 1 P04626 100.0 0.0 X-RAY
 2018-04-25 LEU A:123 A:123 7.0 0.041 -58.9 82.5 7.0 0.041 0.0
1s78 1 P04626 100.0 0.0 X-RAY
 2004-04-27 LEU A:123 A:123 4.0 0.024 -62.9 96.2 4.0 0.024 0.0
LEU B:123 B:123 4.0 0.024 -64.3 93.9 NA NA NA
3be1 1 P04626 100.0 0.0 X-RAY
 2008-11-18 LEU A:123 A:123 7.0 0.041 -74.2 95.6 7.0 0.041 0.0
3mzw 1 P04626 100.0 0.0 X-RAY
 2010-07-28 LEU A:123 A:123 2.0 0.012 -79.3 105.8 2.0 0.012 0.0
3n85 1 P04626 100.0 0.0 X-RAY
 2010-07-28 LEU A:123 A:123 2.0 0.012 -66.4 107.5 2.0 0.012 0.0
5my6 1 P04626 100.0 0.0 X-RAY
 2017-08-09 LEU A:122 A:145 4.0 0.024 -74.9 102.8 4.0 0.024 0.0 HOH
 2.547
 O
 O
6oge 1 P04626 100.0 0.0 EM
 2019-05-15 LEU A:123 A:145 12.0 0.071 -73.2 122.7 12.0 0.071 0.0
6j71 1 P04626 100.0 0.0 X-RAY
 2019-02-27 LEU A:124 A:145 6.0 0.035 -75.8 99.0 6.0 0.035 0.0
1n8z 3 P04626 100.0 0.0 X-RAY
 2003-02-18 LEU C:123 C:123 3.0 0.018 -72.9 102.3 3.0 0.018 0.0 HOH
 9.169
 CD2
 O
5k33 2 P04626 100.0 0.0 X-RAY
 2017-04-12 LEU B:123 C:123 3.0 0.018 -65.0 95.1 3.0 0.018 0.0
5o4g 1 P04626 100.0 0.0 X-RAY
 2018-05-16 LEU A:123 C:123 3.0 0.018 -65.9 98.3 3.0 0.018 0.0
3wlw 1 P04626 100.0 0.0 X-RAY
 2015-05-27 LEU A:123 A:123 6.0 0.035 -71.8 87.4 6.0 0.035 0.0 HOH
 9.461
 N
 O
LEU B:123 B:123 3.0 0.018 -66.1 85.6 NA NA NA
3wsq 1 P04626 100.0 0.0 X-RAY
 2015-03-25 LEU A:123 A:123 7.0 0.041 -59.3 89.3 7.0 0.041 0.0
1n8y 1 22651765 85.53 0.0 X-RAY
 2003-02-18 LEU A:124 C:124 3.0 0.018 -77.5 97.1 3.0 0.018 0.0 HOH
 3.160
 N
 O
2a91 1 P04626 99.61 0.0 X-RAY
 2005-07-26 LEU A:124 A:124 4.0 0.024 -71.1 97.4 4.0 0.024 0.0 HOH
 2.595
 O
 O
4hrl 1 P04626 98.47 3e-130 X-RAY
 2013-10-16 LEU A:123 C:123 11.0 0.065 -75.4 121.1 11.0 0.065 0.0 HOH
 6.917
 O
 O
4hrm 1 P04626 98.47 3e-130 X-RAY
 2013-10-16 LEU A:123 C:123 23.0 0.135 -70.7 114.1 23.0 0.135 0.0
LEU B:123 A:123 25.0 0.147 -62.0 138.9 25.0 0.147 0.0
3h3b 1 P04626 99.48 3e-130 X-RAY
 2010-04-28 LEU A:125 A:123 3.0 0.018 -66.1 116.1 3.0 0.018 0.0 HOH
 2.723
 O
 O
LEU B:125 B:123 5.0 0.029 -71.0 118.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04626-f1 1 P04626 100.0 0.0 LEU A:145 A:145 4.0 0.024 -73.7 103.4