Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37866081 . C A CCDS32642.1:NM_004448.2:c.590cCg>cAg_NP_004439.2:p.197P>Q Homo sapiens v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (ERBB2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7mn5 3 P04626,P0AEX9 99.9 0.0 EM
 2021-10-27 PRO C:197 B:197 130.0 0.897 T -51.4 -23.3 130.0 0.897 0.0
7mn6 2 P04626,P0AEX9 99.81 0.0 EM
 2021-10-27 PRO B:197 B:197 112.0 0.772 T -53.9 -14.0 112.0 0.772 0.0
7mn8 3 P04626,P0AEX9 99.81 0.0 EM
 2021-11-10 PRO C:197 B:197 129.0 0.89 T -51.0 -26.3 129.0 0.89 0.0
6bgt 1 P04626 100.0 0.0 X-RAY
 2018-10-31 PRO A:197 C:175 111.0 0.766 T -55.8 -16.2 111.0 0.766 0.0 HOH
 4.042
 CD
 O
5kwg 1 P04626 100.0 0.0 X-RAY
 2017-04-12 PRO A:175 C:175 125.0 0.862 T -70.7 -17.4 125.0 0.862 0.0
6att 1 P04626 100.0 0.0 X-RAY
 2018-04-25 PRO A:175 A:175 127.0 0.876 T -50.9 -17.1 127.0 0.876 0.0
1s78 1 P04626 100.0 0.0 X-RAY
 2004-04-27 PRO A:175 A:175 133.0 0.917 T -51.2 -27.9 133.0 0.917 0.0
PRO B:175 B:175 133.0 0.917 T -51.0 -27.0 NA NA NA
3be1 1 P04626 100.0 0.0 X-RAY
 2008-11-18 PRO A:175 A:175 137.0 0.945 T -61.1 -12.4 137.0 0.945 0.0
3mzw 1 P04626 100.0 0.0 X-RAY
 2010-07-28 PRO A:175 A:175 136.0 0.938 T -59.4 -14.2 136.0 0.938 0.0
3n85 1 P04626 100.0 0.0 X-RAY
 2010-07-28 PRO A:175 A:175 131.0 0.903 T -49.9 -26.4 131.0 0.903 0.0
5my6 1 P04626 100.0 0.0 X-RAY
 2017-08-09 PRO A:174 A:197 128.0 0.883 T -60.2 -17.5 128.0 0.883 0.0 GOL
HOH
 9.469
6.000
 N
N
 O3
O
6oge 1 P04626 100.0 0.0 EM
 2019-05-15 PRO A:175 A:197 113.0 0.779 T -74.8 5.2 113.0 0.779 0.0
6j71 1 P04626 100.0 0.0 X-RAY
 2019-02-27 PRO A:176 A:197 102.0 0.703 T -62.5 -22.6 31.0 0.214 0.489 B:None:0.49
1n8z 3 P04626 100.0 0.0 X-RAY
 2003-02-18 PRO C:175 C:175 136.0 0.938 T -55.1 -17.5 136.0 0.938 0.0 HOH
 6.119
 O
 O
5k33 2 P04626 100.0 0.0 X-RAY
 2017-04-12 PRO B:175 C:175 125.0 0.862 T -63.6 -9.7 125.0 0.862 0.0
5o4g 1 P04626 100.0 0.0 X-RAY
 2018-05-16 PRO A:175 C:175 135.0 0.931 T -51.8 -16.3 133.0 0.917 0.014 C:None:0.014
3wlw 1 P04626 100.0 0.0 X-RAY
 2015-05-27 PRO A:175 A:175 127.0 0.876 T -52.3 -26.9 8.0 0.055 0.821 F:None:0.821
PRO B:175 B:175 126.0 0.869 T -49.9 -46.6 NA NA NA
3wsq 1 P04626 100.0 0.0 X-RAY
 2015-03-25 PRO A:175 A:175 129.0 0.89 T -57.5 -51.4 129.0 0.89 0.0
1n8y 1 22651765 85.53 0.0 X-RAY
 2003-02-18 PRO A:176 C:176 133.0 0.917 T -50.5 -43.7 133.0 0.917 0.0 HOH
 6.427
 N
 O
2a91 1 P04626 99.61 0.0 X-RAY
 2005-07-26 PRO A:176 A:176 129.0 0.89 T -59.9 -28.7 129.0 0.89 0.0
4hrl 1 P04626 98.47 3e-130 X-RAY
 2013-10-16 PRO A:175 C:175 131.0 0.903 T -58.3 -14.2 131.0 0.903 0.0 HOH
 5.976
 N
 O
4hrm 1 P04626 98.47 3e-130 X-RAY
 2013-10-16 PRO A:175 C:175 134.0 0.924 T -59.9 -30.2 134.0 0.924 0.0
PRO B:175 NA:NA DO NA DO DO DO NA NA NA
3h3b 1 P04626 99.48 3e-130 X-RAY
 2010-04-28 PRO A:177 A:175 122.0 0.841 T -60.1 -19.2 92.0 0.634 0.207 C:None:0.207
 HOH
 3.723
 CG
 O
PRO B:177 B:175 127.0 0.876 T -62.7 -13.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04626-f1 1 P04626 100.0 0.0 PRO A:197 A:197 134.0 0.924 T -57.7 -14.1