Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37866096 . C A CCDS32642.1:NM_004448.2:c.605tCc>tAc_NP_004439.2:p.202S>Y Homo sapiens v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (ERBB2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7mn5 3 P04626,P0AEX9 99.9 0.0 EM
 2021-10-27 SER C:202 B:202 79.0 0.687 G 55.4 38.8 79.0 0.687 0.0
7mn6 2 P04626,P0AEX9 99.81 0.0 EM
 2021-10-27 SER B:202 B:202 89.0 0.774 S 58.6 38.1 89.0 0.774 0.0
7mn8 3 P04626,P0AEX9 99.81 0.0 EM
 2021-11-10 SER C:202 B:202 83.0 0.722 S 57.8 43.0 83.0 0.722 0.0
6bgt 1 P04626 100.0 0.0 X-RAY
 2018-10-31 SER A:202 C:180 79.0 0.687 S 55.8 31.9 79.0 0.687 0.0 HOH
 7.344
 C
 O
5kwg 1 P04626 100.0 0.0 X-RAY
 2017-04-12 SER A:180 C:180 66.0 0.574 S -126.7 46.0 66.0 0.574 0.0
6att 1 P04626 100.0 0.0 X-RAY
 2018-04-25 SER A:180 A:180 89.0 0.774 S -76.9 87.2 89.0 0.774 0.0
1s78 1 P04626 100.0 0.0 X-RAY
 2004-04-27 SER A:180 A:180 77.0 0.67 S -59.8 -9.6 77.0 0.67 0.0
SER B:180 B:180 76.0 0.661 S -59.8 -8.6 NA NA NA
3be1 1 P04626 100.0 0.0 X-RAY
 2008-11-18 SER A:180 A:180 81.0 0.704 S 52.4 45.0 81.0 0.704 0.0
3mzw 1 P04626 100.0 0.0 X-RAY
 2010-07-28 SER A:180 A:180 93.0 0.809 S -111.7 57.9 93.0 0.809 0.0
3n85 1 P04626 100.0 0.0 X-RAY
 2010-07-28 SER A:180 A:180 93.0 0.809 S 61.6 26.7 93.0 0.809 0.0
5my6 1 P04626 100.0 0.0 X-RAY
 2017-08-09 SER A:179 A:202 90.0 0.783 G 60.3 41.0 90.0 0.783 0.0 GOL
HOH
 6.341
2.678
 O
O
 O3
O
6oge 1 P04626 100.0 0.0 EM
 2019-05-15 SER A:180 A:202 80.0 0.696 S -93.1 25.0 80.0 0.696 0.0
6j71 1 P04626 100.0 0.0 X-RAY
 2019-02-27 SER A:181 A:202 87.0 0.757 S 60.7 41.8 54.0 0.47 0.287 B:None:0.287
1n8z 3 P04626 100.0 0.0 X-RAY
 2003-02-18 SER C:180 C:180 78.0 0.678 S -70.8 11.1 78.0 0.678 0.0 HOH
 4.557
 N
 O
5k33 2 P04626 100.0 0.0 X-RAY
 2017-04-12 SER B:180 C:180 64.0 0.557 T 66.5 39.3 64.0 0.557 0.0
5o4g 1 P04626 100.0 0.0 X-RAY
 2018-05-16 SER A:180 C:180 78.0 0.678 S 58.9 45.1 7.0 0.061 0.617 C:None:0.617
3wlw 1 P04626 100.0 0.0 X-RAY
 2015-05-27 SER A:180 A:180 66.0 0.574 S 47.1 64.3 21.0 0.183 0.391 F:None:0.391
 HOH
 8.079
 N
 O
SER B:180 B:180 66.0 0.574 S 36.4 71.5 NA NA NA
3wsq 1 P04626 100.0 0.0 X-RAY
 2015-03-25 SER A:180 A:180 81.0 0.704 S -79.2 -7.8 81.0 0.704 0.0
1n8y 1 22651765 85.53 0.0 X-RAY
 2003-02-18 ASN A:181 C:181 108.0 0.675 S -74.9 47.0 108.0 0.675 0.0 HOH
 8.058
 OD1
 O
2a91 1 P04626 99.61 0.0 X-RAY
 2005-07-26 SER A:181 A:181 85.0 0.739 S 56.9 36.8 85.0 0.739 0.0 HOH
 8.518
 O
 O
4hrl 1 P04626 98.47 3e-130 X-RAY
 2013-10-16 SER A:180 C:180 120.0 1.0 360.0 46.5 120.0 1.0 0.0 HOH
 7.450
 C
 O
4hrm 1 P04626 98.47 3e-130 X-RAY
 2013-10-16 SER A:180 C:180 108.0 NA 360.0 56.7 108.0 NA NA
SER B:180 NA:NA DO NA DO DO DO NA NA NA
3h3b 1 P04626 99.48 3e-130 X-RAY
 2010-04-28 SER A:182 A:180 81.0 0.704 S 59.4 36.1 75.0 0.652 0.052 C:None:0.052
 HOH
 3.979
 CB
 O
SER B:182 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04626-f1 1 P04626 100.0 0.0 SER A:202 A:202 87.0 0.757 S 60.2 43.7