Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr17 | 45730168 | . | C | A | CCDS11513.1:NM_002265.5:c.208Cca>Aca_NP_002256.2:p.70P>T | Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
2p8q | 1 | Q14974 | 100.0 | 0.0 |
X-RAY |
2008-01-22 | PRO | A:70 | A:70 | 96.0 | 0.662 | H | -52.0 | -40.1 | 96.0 | 0.662 | 0.0 |
HOH |
7.768 |
N |
O |
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2q5d | 1 | Q14974 | 100.0 | 0.0 |
X-RAY |
2008-01-22 | PRO | A:70 | A:70 | 32.0 | 0.221 | H | -56.1 | -38.1 | 32.0 | 0.221 | 0.0 | ||||||
PRO | C:70 | B:70 | 110.0 | 0.759 | S | -55.1 | -62.2 | NA | NA | NA | |||||||||||||
3lww | 1 | Q14974 | 100.0 | 0.0 |
X-RAY |
2010-06-02 | PRO | A:70 | A:70 | 99.0 | 0.683 | H | -47.1 | -57.0 | 99.0 | 0.683 | 0.0 | ||||||
PRO | C:70 | C:70 | 29.0 | 0.2 | H | -73.0 | -34.3 | NA | NA | NA | |||||||||||||
3w5k | 1 | Q14974 | 100.0 | 0.0 |
X-RAY |
2014-03-05 | PRO | A:70 | A:70 | 81.0 | 0.559 | H | -59.1 | -24.1 | 66.0 | 0.455 | 0.104 |
B:O95863:0.103 |
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6n88 | 2 | Q14974 | 100.0 | 0.0 |
EM |
2019-02-27 | PRO | B:70 | B:70 | 125.0 | 0.862 | H | -65.2 | -45.2 | 125.0 | 0.862 | 0.0 | ||||||
6n89 | 1 | Q14974 | 100.0 | 0.0 |
EM |
2019-02-27 | PRO | A:70 | A:70 | 71.0 | NA | H | -46.1 | -54.8 | 59.0 | NA | NA |
B:P07305:NA |
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1qgk | 1 | Q14974 | 99.77 | 0.0 |
X-RAY |
1999-05-24 | PRO | A:70 | A:70 | 108.0 | 0.745 | H | -50.9 | -29.6 | 108.0 | 0.745 | 0.0 | ||||||
1qgr | 1 | Q14974 | 99.77 | 0.0 |
X-RAY |
1999-05-24 | PRO | A:70 | A:70 | 41.0 | 0.283 | H | -48.7 | -40.4 | 41.0 | 0.283 | 0.0 |
HOH |
5.100 |
CB |
O |
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1ukl | 1 | P70168 | 99.2 | 0.0 |
X-RAY |
2003-12-09 | PRO | A:70 | A:70 | 131.0 | 0.903 | T | -40.7 | -9.3 | 131.0 | 0.903 | 0.0 | ||||||
PRO | B:70 | B:70 | 121.0 | 0.834 | T | -45.3 | -42.6 | NA | NA | NA | |||||||||||||
1m5n | 1 | Q14974 | 100.0 | 0.0 |
X-RAY |
2003-01-21 | PRO | A:70 | S:70 | 119.0 | 0.821 | T | -49.2 | -7.4 | 119.0 | 0.821 | 0.0 |
HOH |
5.849 |
O |
O |
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1ibr | 2 | Q14974 | 100.0 | 0.0 |
X-RAY |
1999-06-03 | PRO | B:70 | B:70 | 89.0 | 0.614 | H | -55.1 | -27.1 | 89.0 | 0.614 | 0.0 |
HOH |
2.602 |
O |
O |
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PRO | D:70 | D:70 | 89.0 | 0.614 | H | -56.0 | -25.8 | NA | NA | NA | |||||||||||||
1gcj | 1 | P70168 | 98.67 | 0.0 |
X-RAY |
2000-10-18 | PRO | A:76 | A:70 | 91.0 | 0.628 | H | -43.3 | -35.1 | 61.0 | 0.421 | 0.207 |
B:P70168:0.207 |
HOH |
3.724 |
CD |
O |
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PRO | B:76 | B:70 | 110.0 | 0.759 | H | -43.5 | -35.5 | 77.0 | 0.531 | 0.228 |
A:P70168:0.228 |
HOH |
5.333 |
O |
O |
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1f59 | 1 | Q14974 | 99.77 | 0.0 |
X-RAY |
2000-08-16 | PRO | A:70 | A:70 | 95.0 | 0.655 | H | -39.6 | -42.2 | 95.0 | 0.655 | 0.0 | ||||||
PRO | B:70 | B:70 | 95.0 | 0.655 | H | -38.6 | -42.3 | NA | NA | NA | |||||||||||||
1o6o | 1 | Q14974 | 99.77 | 0.0 |
X-RAY |
2003-10-17 | PRO | A:70 | A:70 | 97.0 | 0.669 | H | -45.8 | -39.5 | 97.0 | 0.669 | 0.0 | ||||||
PRO | B:70 | B:70 | 95.0 | 0.655 | H | -46.4 | -40.8 | NA | NA | NA | |||||||||||||
PRO | C:70 | C:70 | 96.0 | 0.662 | H | -41.0 | -41.7 | NA | NA | NA | |||||||||||||
1o6p | 1 | Q14974 | 99.77 | 0.0 |
X-RAY |
2003-04-24 | PRO | A:70 | A:70 | 91.0 | 0.628 | H | -42.7 | -40.0 | 91.0 | 0.628 | 0.0 |
HOH |
8.242 |
O |
O |
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PRO | B:70 | B:70 | 93.0 | 0.641 | H | -41.2 | -42.6 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q14974-f1 | 1 | Q14974 | 100.0 | 0.0 | PRO | A:70 | A:70 | 84.0 | 0.579 | H | -59.3 | -36.7 |