Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 45730207 . A C CCDS11513.1:NM_002265.5:c.247Att>Ctt_NP_002256.2:p.83I>L Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2p8q 1 Q14974 100.0 0.0 X-RAY
 2008-01-22 ILE A:83 A:83 17.0 0.097 S -83.3 144.5 17.0 0.097 0.0 HOH
 2.817
 O
 O
2q5d 1 Q14974 100.0 0.0 X-RAY
 2008-01-22 ILE A:83 A:83 23.0 0.131 S -81.0 166.9 23.0 0.131 0.0
ILE C:83 B:83 20.0 0.114 S -83.2 144.5 NA NA NA
3lww 1 Q14974 100.0 0.0 X-RAY
 2010-06-02 ILE A:83 A:83 18.0 0.103 S -67.4 143.3 18.0 0.103 0.0
ILE C:83 C:83 19.0 0.109 S -98.1 146.8 NA NA NA
3w5k 1 Q14974 100.0 0.0 X-RAY
 2014-03-05 ILE A:83 A:83 17.0 0.097 S -67.5 144.8 17.0 0.097 0.0 HOH
 7.006
 O
 O
6n88 2 Q14974 100.0 0.0 EM
 2019-02-27 ILE B:83 B:83 6.0 NA S -96.0 132.5 6.0 NA NA
6n89 1 Q14974 100.0 0.0 EM
 2019-02-27 ILE A:83 A:83 32.0 NA S -65.0 146.7 32.0 NA NA
1qgk 1 Q14974 99.77 0.0 X-RAY
 1999-05-24 ILE A:83 A:83 17.0 0.097 S -68.3 148.5 17.0 0.097 0.0 HOH
 5.452
 CD1
 O
1qgr 1 Q14974 99.77 0.0 X-RAY
 1999-05-24 ILE A:83 A:83 18.0 0.103 S -81.2 144.2 18.0 0.103 0.0 HOH
 3.688
 CA
 O
1ukl 1 P70168 99.2 0.0 X-RAY
 2003-12-09 ILE A:83 A:83 29.0 0.166 S -79.8 173.1 29.0 0.166 0.0
ILE B:83 B:83 34.0 0.194 S -86.9 154.9 NA NA NA
1m5n 1 Q14974 100.0 0.0 X-RAY
 2003-01-21 ILE A:83 S:83 31.0 0.177 S -89.4 173.9 31.0 0.177 0.0
1ibr 2 Q14974 100.0 0.0 X-RAY
 1999-06-03 ILE B:83 B:83 19.0 0.109 S -70.7 147.6 19.0 0.109 0.0 HOH
 2.649
 O
 O
ILE D:83 D:83 21.0 0.12 S -69.7 148.5 NA NA NA
1gcj 1 P70168 98.67 0.0 X-RAY
 2000-10-18 ILE A:89 A:83 14.0 0.08 S -58.3 142.1 14.0 0.08 0.0 HOH
 4.123
 N
 O
ILE B:89 B:83 17.0 0.097 S -57.3 142.3 17.0 0.097 0.0 HOH
 2.915
 CG2
 O
1f59 1 Q14974 99.77 0.0 X-RAY
 2000-08-16 ILE A:83 A:83 21.0 0.12 S -83.9 163.4 21.0 0.12 0.0
ILE B:83 B:83 17.0 0.097 S -84.4 162.5 NA NA NA
1o6o 1 Q14974 99.77 0.0 X-RAY
 2003-10-17 ILE A:83 A:83 16.0 0.091 S -69.7 151.4 16.0 0.091 0.0
ILE B:83 B:83 15.0 0.086 S -64.3 151.7 NA NA NA
ILE C:83 C:83 17.0 0.097 S -68.2 150.1 NA NA NA
1o6p 1 Q14974 99.77 0.0 X-RAY
 2003-04-24 ILE A:83 A:83 19.0 0.109 S -76.1 151.2 19.0 0.109 0.0 HOH
 3.682
 CA
 O
ILE B:83 B:83 16.0 0.091 S -78.5 150.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14974-f1 1 Q14974 100.0 0.0 ILE A:83 A:83 15.0 0.086 S -70.2 145.3