Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 45735931 . A C CCDS11513.1:NM_002265.5:c.541Atg>Ctg_NP_002256.2:p.181M>L Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2p8q 1 Q14974 100.0 0.0 X-RAY
 2008-01-22 MET A:181 A:181 6.0 0.032 H -91.9 -19.5 6.0 0.032 0.0 HOH
 2.774
 O
 O
2q5d 1 Q14974 100.0 0.0 X-RAY
 2008-01-22 MET A:181 A:181 9.0 0.049 T -94.5 4.4 9.0 0.049 0.0
MET C:181 B:181 6.0 0.032 H -94.5 -13.9 NA NA NA
3lww 1 Q14974 100.0 0.0 X-RAY
 2010-06-02 MET A:181 A:181 2.0 0.011 H -92.8 -18.4 2.0 0.011 0.0
MET C:181 C:181 4.0 0.022 H -100.6 -21.4 NA NA NA
3w5k 1 Q14974 100.0 0.0 X-RAY
 2014-03-05 MET A:181 A:181 5.0 0.027 H -91.0 -18.3 5.0 0.027 0.0 HOH
 2.393
 O
 O
6n88 2 Q14974 100.0 0.0 EM
 2019-02-27 MET B:181 B:181 69.0 NA H -63.5 -42.2 69.0 NA NA
6n89 1 Q14974 100.0 0.0 EM
 2019-02-27 MET A:181 A:181 58.0 NA -91.5 -1.5 58.0 NA NA
1qgk 1 Q14974 99.77 0.0 X-RAY
 1999-05-24 MET A:181 A:181 6.0 0.032 H -88.7 -13.2 6.0 0.032 0.0 HOH
 3.004
 O
 O
1qgr 1 Q14974 99.77 0.0 X-RAY
 1999-05-24 MET A:181 A:181 4.0 0.022 H -88.0 -13.1 4.0 0.022 0.0 HOH
 2.607
 O
 O
1ukl 1 P70168 99.2 0.0 X-RAY
 2003-12-09 MET A:181 A:181 7.0 0.038 T -105.7 -25.4 7.0 0.038 0.0
MET B:181 B:181 6.0 0.032 H -110.7 -14.2 NA NA NA
2qna 1 Q14974 99.87 0.0 X-RAY
 2008-04-08 MET A:56 A:181 4.0 0.022 H -89.0 -21.6 4.0 0.022 0.0
1m5n 1 Q14974 100.0 0.0 X-RAY
 2003-01-21 MET A:181 S:181 6.0 0.032 H -90.1 -18.7 6.0 0.032 0.0 HOH
 7.623
 O
 O
1ibr 2 Q14974 100.0 0.0 X-RAY
 1999-06-03 MET B:181 B:181 2.0 0.011 H -89.9 -33.9 2.0 0.011 0.0 HOH
 7.505
 N
 O
MET D:181 D:181 1.0 0.005 H -89.9 -26.3 NA NA NA
1gcj 1 P70168 98.67 0.0 X-RAY
 2000-10-18 MSE A:187 A:181 3.0 0.016 H -102.0 -7.5 3.0 0.016 0.0 HOH
 9.543
 N
 O
MSE B:187 B:181 4.0 0.022 H -105.9 -3.9 4.0 0.022 0.0 HOH
 2.896
 O
 O
1f59 1 Q14974 99.77 0.0 X-RAY
 2000-08-16 MET A:181 A:181 4.0 0.022 T -111.4 -15.3 4.0 0.022 0.0
MET B:181 B:181 5.0 0.027 T -112.5 -14.9 NA NA NA
1o6o 1 Q14974 99.77 0.0 X-RAY
 2003-10-17 MET A:181 A:181 5.0 0.027 H -94.3 -20.3 5.0 0.027 0.0
MET B:181 B:181 4.0 0.022 H -90.9 -23.2 NA NA NA
MET C:181 C:181 5.0 0.027 H -92.2 -22.3 NA NA NA
1o6p 1 Q14974 99.77 0.0 X-RAY
 2003-04-24 MET A:181 A:181 3.0 0.016 T -107.3 -25.9 3.0 0.016 0.0
MET B:181 B:181 3.0 0.016 H -106.5 -30.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14974-f1 1 Q14974 100.0 0.0 MET A:181 A:181 5.0 0.027 H -84.7 -20.9