Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 45745694 . G A CCDS11513.1:NM_002265.5:c.1142cGg>cAg_NP_002256.2:p.381R>Q Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2p8q 1 Q14974 100.0 0.0 X-RAY
 2008-01-22 ARG A:381 A:381 65.0 0.289 H -60.5 -38.0 65.0 0.289 0.0 HOH
 3.084
 NE
 O
2q5d 1 Q14974 100.0 0.0 X-RAY
 2008-01-22 ARG A:381 A:381 75.0 0.333 H -50.0 -43.4 75.0 0.333 0.0
ARG C:381 B:381 90.0 0.4 H -51.8 -60.2 NA NA NA
3lww 1 Q14974 100.0 0.0 X-RAY
 2010-06-02 ARG A:381 A:381 70.0 0.311 H -74.4 -23.4 70.0 0.311 0.0
ARG C:381 C:381 68.0 0.302 H -69.4 -31.0 NA NA NA
3w5k 1 Q14974 100.0 0.0 X-RAY
 2014-03-05 ARG A:381 A:381 71.0 0.316 H -66.4 -29.2 71.0 0.316 0.0 HOH
 7.459
 O
 O
6n88 2 Q14974 100.0 0.0 EM
 2019-02-27 ARG B:381 B:381 67.0 NA H -66.8 -40.7 67.0 NA NA
6n89 1 Q14974 100.0 0.0 EM
 2019-02-27 ARG A:381 A:381 31.0 NA T -75.2 -24.9 31.0 NA NA
1qgk 1 Q14974 99.77 0.0 X-RAY
 1999-05-24 ARG A:381 A:381 79.0 0.351 H -57.1 -42.0 79.0 0.351 0.0 HOH
 5.403
 N
 O
1qgr 1 Q14974 99.77 0.0 X-RAY
 1999-05-24 ARG A:381 A:381 57.0 0.253 H -60.1 -48.3 57.0 0.253 0.0 HOH
 2.916
 CD
 O
1ukl 1 P70168 99.2 0.0 X-RAY
 2003-12-09 ARG A:381 A:381 57.0 0.253 H -65.8 -27.1 57.0 0.253 0.0
ARG B:381 B:381 67.0 0.298 H -55.9 -41.1 NA NA NA
2qna 1 Q14974 99.87 0.0 X-RAY
 2008-04-08 ARG A:256 A:381 63.0 0.28 H -68.4 -33.4 63.0 0.28 0.0 HOH
 5.211
 CD
 O
1m5n 1 Q14974 100.0 0.0 X-RAY
 2003-01-21 ARG A:381 S:381 54.0 0.24 H -43.8 -60.1 54.0 0.24 0.0 HOH
 3.133
 NE
 O
1ibr 2 Q14974 100.0 0.0 X-RAY
 1999-06-03 ARG B:381 B:381 90.0 0.4 H -57.2 -48.6 90.0 0.4 0.0 HOH
 3.008
 NH1
 O
ARG D:381 D:381 92.0 0.409 H -57.3 -48.4 NA NA NA
1gcj 1 P70168 98.67 0.0 X-RAY
 2000-10-18 ARG A:387 A:381 69.0 0.307 H -58.0 -37.1 69.0 0.307 0.0 HOH
 3.175
 CD
 O
ARG B:387 B:381 70.0 0.311 H -60.3 -34.7 70.0 0.311 0.0 HOH
 3.711
 CD
 O
1f59 1 Q14974 99.77 0.0 X-RAY
 2000-08-16 ARG A:381 A:381 52.0 0.231 H -65.9 -58.2 52.0 0.231 0.0
ARG B:381 B:381 71.0 0.316 H -65.3 -59.3 NA NA NA
1o6o 1 Q14974 99.77 0.0 X-RAY
 2003-10-17 ARG A:381 A:381 58.0 0.258 H -54.8 -54.4 58.0 0.258 0.0
ARG B:381 B:381 54.0 0.24 H -58.5 -52.1 NA NA NA
ARG C:381 C:381 60.0 0.267 H -54.6 -55.6 NA NA NA
1o6p 1 Q14974 99.77 0.0 X-RAY
 2003-04-24 ARG A:381 A:381 41.0 0.182 H -60.3 -59.5 41.0 0.182 0.0
ARG B:381 B:381 39.0 0.173 H -60.4 -60.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14974-f1 1 Q14974 100.0 0.0 ARG A:381 A:381 82.0 0.364 H -62.6 -44.0