Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 45748110 . G A CCDS11513.1:NM_002265.5:c.1459Gtt>Att_NP_002256.2:p.487V>I Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 1, mRNA.
pdb_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2p8q 1 Q14974 100.0 0.0 X-RAY
 2008-01-22 VAL A:487 A:487 122.0 0.787 S -76.7 -67.1 122.0 0.787 0.0 HOH
 6.109
 N
 O
2q5d 1 Q14974 100.0 0.0 X-RAY
 2008-01-22 VAL A:487 A:487 124.0 0.8 S -65.8 -45.3 124.0 0.8 0.0
VAL C:487 B:487 122.0 0.787 S -60.8 -43.9 NA NA NA
3lww 1 Q14974 100.0 0.0 X-RAY
 2010-06-02 VAL A:487 A:487 115.0 0.742 S -92.2 -12.7 115.0 0.742 0.0
VAL C:487 C:487 108.0 0.697 T -128.5 64.3 NA NA NA
3w5k 1 Q14974 100.0 0.0 X-RAY
 2014-03-05 VAL A:487 NA:NA DO NA DO DO DO NA NA NA
6n88 2 Q14974 100.0 0.0 EM
 2019-02-27 VAL B:487 B:487 36.0 NA S -131.7 -59.4 36.0 NA NA
6n89 1 Q14974 100.0 0.0 EM
 2019-02-27 VAL A:487 A:487 79.0 NA 54.0 -133.6 79.0 NA NA
1qgk 1 Q14974 99.77 0.0 X-RAY
 1999-05-24 VAL A:487 A:487 115.0 0.742 G -49.1 -35.6 115.0 0.742 0.0 HOH
 7.778
 CG2
 O
1qgr 1 Q14974 99.77 0.0 X-RAY
 1999-05-24 VAL A:487 A:487 96.0 0.619 61.3 -94.9 96.0 0.619 0.0
1ukl 1 P70168 99.2 0.0 X-RAY
 2003-12-09 VAL A:487 A:487 131.0 0.845 G -67.3 -14.8 131.0 0.845 0.0
VAL B:487 B:487 102.0 0.658 -115.5 166.6 NA NA NA
2qna 1 Q14974 99.87 0.0 X-RAY
 2008-04-08 VAL A:362 A:487 63.0 0.406 -124.5 112.0 63.0 0.406 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14974-f1 1 Q14974 100.0 0.0 VAL A:487 A:487 70.0 0.452 -96.2 118.8