Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 45757935 . C A CCDS11513.1:NM_002265.5:c.2530Cat>Aat_NP_002256.2:p.844H>N Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 1, mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2p8q 1 Q14974 100.0 0.0 X-RAY
 2008-01-22 HIS A:844 A:844 75.0 0.385 H -57.7 -46.7 75.0 0.385 0.0 HOH
 3.099
 O
 O
2q5d 1 Q14974 100.0 0.0 X-RAY
 2008-01-22 HIS A:844 A:844 77.0 0.395 H -65.4 -40.4 77.0 0.395 0.0
HIS C:844 B:844 75.0 0.385 T -65.6 -8.4 NA NA NA
3lww 1 Q14974 100.0 0.0 X-RAY
 2010-06-02 HIS A:844 A:844 66.0 0.338 H -79.5 -21.2 66.0 0.338 0.0
HIS C:844 C:844 75.0 0.385 H -69.2 -39.1 NA NA NA
3w5k 1 Q14974 100.0 0.0 X-RAY
 2014-03-05 HIS A:844 A:844 69.0 0.354 H -65.9 -27.6 69.0 0.354 0.0
6n88 2 Q14974 100.0 0.0 EM
 2019-02-27 HIS B:844 B:844 47.0 NA H -61.4 -39.7 47.0 NA NA
6n89 1 Q14974 100.0 0.0 EM
 2019-02-27 HIS A:844 A:844 67.0 NA H -79.4 -26.1 67.0 NA NA
1qgk 1 Q14974 99.77 0.0 X-RAY
 1999-05-24 HIS A:844 A:844 69.0 0.354 H -66.5 -40.6 69.0 0.354 0.0
1qgr 1 Q14974 99.77 0.0 X-RAY
 1999-05-24 HIS A:844 A:844 107.0 0.549 H -58.1 -39.5 107.0 0.549 0.0 HOH
 5.711
 O
 O
1ukl 1 P70168 99.2 0.0 X-RAY
 2003-12-09 HIS A:844 A:844 105.0 0.538 H -58.2 -39.0 105.0 0.538 0.0
HIS B:844 B:844 80.0 0.41 H -79.1 -52.6 NA NA NA
2qna 1 Q14974 99.87 0.0 X-RAY
 2008-04-08 HIS A:719 A:844 115.0 0.59 H -57.7 -44.0 115.0 0.59 0.0 HOH
 3.629
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14974-f1 1 Q14974 100.0 0.0 HIS A:844 A:844 73.0 0.374 H -71.4 -31.6