Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 4849265 . C A CCDS11061.1:NM_005022.3:c.353gGt>gTt_NP_005013.1:p.118G>V Homo sapiens profilin 1 (PFN1), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4x1l 1 P07737 100.0 4e-103 X-RAY
2015-06-10 GLY A:118 A:118 84.0 1.0 T 79.6 6.2 84.0 1.0 0.0 PO4
HOH
5.823
5.050
C
N
O3
O
6nas 3 P07737 100.0 4e-103 X-RAY
2020-01-29 GLY C:118 P:117 73.0 0.973 T 82.7 -18.9 47.0 0.627 0.346 A:P68135:0.347
HOH
8.901
O
O
6nbe 3 P07737 100.0 4e-103 X-RAY
2020-04-15 GLY C:118 P:117 76.0 1.0 T 79.6 -8.9 47.0 0.627 0.373 A:P68135:0.387
HOH
1.989
H
O
6nbw 3 P07737 100.0 4e-103 X-RAY
2020-01-29 GLY C:118 P:117 78.0 1.0 T 81.7 -13.4 56.0 0.747 0.253 A:P60709:0.293
HOH
2.158
H
O
7p1h 3 P07737 100.0 4e-103 EM
2021-11-17 GLY C:118 P:117 65.0 0.867 T 70.0 -10.1 16.0 0.213 0.654 B:P60709:0.12
A:P0AEX9+A0A0F6NGV0:0.533
1cjf 1 P07737 100.0 3e-102 X-RAY
1999-07-07 GLY A:117 A:117 82.0 1.0 T 87.0 9.4 82.0 1.0 0.0
GLY C:117 B:117 78.0 1.0 T 90.5 -7.6 78.0 1.0 0.0 HOH
2.966
N
O
1fik 1 P07737 100.0 3e-102 X-RAY
1996-11-08 GLY A:117 A:117 79.0 1.0 T 74.5 9.7 79.0 1.0 0.0 PO4
HOH
5.744
4.334
C
C
O3
O
1fil 1 P07737 100.0 3e-102 X-RAY
1996-11-08 GLY A:117 A:117 76.0 1.0 T 74.8 9.4 76.0 1.0 0.0 SO4
HOH
5.949
3.806
C
N
O3
O
1pfl 1 P07737 100.0 3e-102 NMR
1995-03-31 GLY A:117 A:117 70.0 0.933 S 53.3 0.6 70.0 0.933 0.0
2pav 2 P07737 100.0 3e-102 X-RAY
2007-10-23 GLY B:117 P:117 76.0 1.0 T 83.0 -7.0 49.0 0.653 0.347 A:P68135:0.36
HOH
2.912
O
O
2pbd 2 P07737 100.0 3e-102 X-RAY
2007-11-13 GLY B:117 P:117 77.0 1.0 T 83.0 -7.9 54.0 0.72 0.28 A:P68135:0.307
HOH
2.792
O
O
3chw 2 P07737 100.0 3e-102 X-RAY
2008-08-19 GLY B:117 P:117 72.0 0.96 T 71.1 9.1 51.0 0.68 0.28 A:P07830:0.28
HOH
2.792
N
O
4x25 1 P07737 99.29 4e-102 X-RAY
2015-06-10 GLY A:118 A:118 86.0 1.0 T 83.3 -8.3 86.0 1.0 0.0 HOH
3.698
N
O
GLY B:118 B:118 89.0 1.0 T 61.1 13.8 NA NA NA
4x1m 1 P07737 99.29 9e-102 X-RAY
2015-06-10 GLY A:118 A:118 92.0 1.0 T 78.9 17.3 92.0 1.0 0.0 HOH
3.220
N
O
1awi 1 P07737 100.0 1e-101 X-RAY
1998-10-28 GLY A:116 A:117 79.0 1.0 T 89.1 -20.2 79.0 1.0 0.0 HOH
4.982
H
H1
GLY B:116 B:117 84.0 1.0 T 88.4 -13.1 84.0 1.0 0.0 HOH
1.896
O
H1
1cf0 1 P07737 100.0 1e-101 X-RAY
1999-07-06 GLY A:116 A:117 77.0 1.0 T 86.2 -9.3 77.0 1.0 0.0 HOH
4.729
C
O
GLY B:116 B:117 82.0 1.0 T 83.3 -2.4 NA NA NA
1hlu 2 P02584 94.96 1e-98 X-RAY
1997-10-15 GLY B:118 P:117 69.0 0.92 T 91.6 24.5 55.0 0.733 0.187 A:P60712:0.187
1pne 1 P02584 94.96 1e-98 X-RAY
1995-07-31 GLY A:118 A:117 77.0 1.0 T 81.3 -1.6 77.0 1.0 0.0 HOH
3.770
CA
O
2btf 2 P02584 94.96 1e-98 X-RAY
1994-06-22 GLY B:118 P:117 77.0 1.0 T 89.7 -5.7 76.0 1.0 0.0 A:P60712:0.013
3u4l 2 P02584 94.96 1e-98 X-RAY
2012-04-25 GLY B:118 P:117 77.0 1.0 T 77.0 9.6 60.0 0.8 0.2 A:P60712:0.227
HOH
8.722
O
O
3ub5 2 P02584 94.96 1e-98 X-RAY
2012-04-25 GLY B:118 P:117 70.0 0.933 T 82.7 -3.8 67.0 0.893 0.04 A:P60712:0.04
HOH
4.443
O
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p07737-f1 1 P07737 100.0 2e-103 GLY A:118 A:118 75.0 1.0 T 75.6 -10.8