Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr17 | 4849265 | . | C | A | CCDS11061.1:NM_005022.3:c.353gGt>gTt_NP_005013.1:p.118G>V | Homo sapiens profilin 1 (PFN1), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4x1l | 1 | P07737 | 100.0 | 4e-103 |
X-RAY |
2015-06-10 | GLY | A:118 | A:118 | 84.0 | 1.0 | T | 79.6 | 6.2 | 84.0 | 1.0 | 0.0 |
PO4 HOH |
5.823 5.050 |
C N |
O3 O |
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6nas | 3 | P07737 | 100.0 | 4e-103 |
X-RAY |
2020-01-29 | GLY | C:118 | P:117 | 73.0 | 0.973 | T | 82.7 | -18.9 | 47.0 | 0.627 | 0.346 |
A:P68135:0.347 |
HOH |
8.901 |
O |
O |
|
6nbe | 3 | P07737 | 100.0 | 4e-103 |
X-RAY |
2020-04-15 | GLY | C:118 | P:117 | 76.0 | 1.0 | T | 79.6 | -8.9 | 47.0 | 0.627 | 0.373 |
A:P68135:0.387 |
HOH |
1.989 |
H |
O |
|
6nbw | 3 | P07737 | 100.0 | 4e-103 |
X-RAY |
2020-01-29 | GLY | C:118 | P:117 | 78.0 | 1.0 | T | 81.7 | -13.4 | 56.0 | 0.747 | 0.253 |
A:P60709:0.293 |
HOH |
2.158 |
H |
O |
|
7p1h | 3 | P07737 | 100.0 | 4e-103 |
EM |
2021-11-17 | GLY | C:118 | P:117 | 65.0 | 0.867 | T | 70.0 | -10.1 | 16.0 | 0.213 | 0.654 |
B:P60709:0.12 A:P0AEX9+A0A0F6NGV0:0.533 |
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1cjf | 1 | P07737 | 100.0 | 3e-102 |
X-RAY |
1999-07-07 | GLY | A:117 | A:117 | 82.0 | 1.0 | T | 87.0 | 9.4 | 82.0 | 1.0 | 0.0 | ||||||
GLY | C:117 | B:117 | 78.0 | 1.0 | T | 90.5 | -7.6 | 78.0 | 1.0 | 0.0 |
HOH |
2.966 |
N |
O |
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1fik | 1 | P07737 | 100.0 | 3e-102 |
X-RAY |
1996-11-08 | GLY | A:117 | A:117 | 79.0 | 1.0 | T | 74.5 | 9.7 | 79.0 | 1.0 | 0.0 |
PO4 HOH |
5.744 4.334 |
C C |
O3 O |
||
1fil | 1 | P07737 | 100.0 | 3e-102 |
X-RAY |
1996-11-08 | GLY | A:117 | A:117 | 76.0 | 1.0 | T | 74.8 | 9.4 | 76.0 | 1.0 | 0.0 |
SO4 HOH |
5.949 3.806 |
C N |
O3 O |
||
1pfl | 1 | P07737 | 100.0 | 3e-102 |
NMR |
1995-03-31 | GLY | A:117 | A:117 | 70.0 | 0.933 | S | 53.3 | 0.6 | 70.0 | 0.933 | 0.0 | ||||||
2pav | 2 | P07737 | 100.0 | 3e-102 |
X-RAY |
2007-10-23 | GLY | B:117 | P:117 | 76.0 | 1.0 | T | 83.0 | -7.0 | 49.0 | 0.653 | 0.347 |
A:P68135:0.36 |
HOH |
2.912 |
O |
O |
|
2pbd | 2 | P07737 | 100.0 | 3e-102 |
X-RAY |
2007-11-13 | GLY | B:117 | P:117 | 77.0 | 1.0 | T | 83.0 | -7.9 | 54.0 | 0.72 | 0.28 |
A:P68135:0.307 |
HOH |
2.792 |
O |
O |
|
3chw | 2 | P07737 | 100.0 | 3e-102 |
X-RAY |
2008-08-19 | GLY | B:117 | P:117 | 72.0 | 0.96 | T | 71.1 | 9.1 | 51.0 | 0.68 | 0.28 |
A:P07830:0.28 |
HOH |
2.792 |
N |
O |
|
4x25 | 1 | P07737 | 99.29 | 4e-102 |
X-RAY |
2015-06-10 | GLY | A:118 | A:118 | 86.0 | 1.0 | T | 83.3 | -8.3 | 86.0 | 1.0 | 0.0 |
HOH |
3.698 |
N |
O |
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GLY | B:118 | B:118 | 89.0 | 1.0 | T | 61.1 | 13.8 | NA | NA | NA | |||||||||||||
4x1m | 1 | P07737 | 99.29 | 9e-102 |
X-RAY |
2015-06-10 | GLY | A:118 | A:118 | 92.0 | 1.0 | T | 78.9 | 17.3 | 92.0 | 1.0 | 0.0 |
HOH |
3.220 |
N |
O |
||
1awi | 1 | P07737 | 100.0 | 1e-101 |
X-RAY |
1998-10-28 | GLY | A:116 | A:117 | 79.0 | 1.0 | T | 89.1 | -20.2 | 79.0 | 1.0 | 0.0 |
HOH |
4.982 |
H |
H1 |
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GLY | B:116 | B:117 | 84.0 | 1.0 | T | 88.4 | -13.1 | 84.0 | 1.0 | 0.0 |
HOH |
1.896 |
O |
H1 |
|||||||||
1cf0 | 1 | P07737 | 100.0 | 1e-101 |
X-RAY |
1999-07-06 | GLY | A:116 | A:117 | 77.0 | 1.0 | T | 86.2 | -9.3 | 77.0 | 1.0 | 0.0 |
HOH |
4.729 |
C |
O |
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GLY | B:116 | B:117 | 82.0 | 1.0 | T | 83.3 | -2.4 | NA | NA | NA | |||||||||||||
1hlu | 2 | P02584 | 94.96 | 1e-98 |
X-RAY |
1997-10-15 | GLY | B:118 | P:117 | 69.0 | 0.92 | T | 91.6 | 24.5 | 55.0 | 0.733 | 0.187 |
A:P60712:0.187 |
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1pne | 1 | P02584 | 94.96 | 1e-98 |
X-RAY |
1995-07-31 | GLY | A:118 | A:117 | 77.0 | 1.0 | T | 81.3 | -1.6 | 77.0 | 1.0 | 0.0 |
HOH |
3.770 |
CA |
O |
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2btf | 2 | P02584 | 94.96 | 1e-98 |
X-RAY |
1994-06-22 | GLY | B:118 | P:117 | 77.0 | 1.0 | T | 89.7 | -5.7 | 76.0 | 1.0 | 0.0 |
A:P60712:0.013 |
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3u4l | 2 | P02584 | 94.96 | 1e-98 |
X-RAY |
2012-04-25 | GLY | B:118 | P:117 | 77.0 | 1.0 | T | 77.0 | 9.6 | 60.0 | 0.8 | 0.2 |
A:P60712:0.227 |
HOH |
8.722 |
O |
O |
|
3ub5 | 2 | P02584 | 94.96 | 1e-98 |
X-RAY |
2012-04-25 | GLY | B:118 | P:117 | 70.0 | 0.933 | T | 82.7 | -3.8 | 67.0 | 0.893 | 0.04 |
A:P60712:0.04 |
HOH |
4.443 |
O |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p07737-f1 | 1 | P07737 | 100.0 | 2e-103 | GLY | A:118 | A:118 | 75.0 | 1.0 | T | 75.6 | -10.8 |