Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 4849277 . A C CCDS11061.1:NM_005022.3:c.341aTg>aGg_NP_005013.1:p.114M>R Homo sapiens profilin 1 (PFN1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4x1l 1 P07737 100.0 4e-103 X-RAY
 2015-06-10 MET A:114 A:114 5.0 0.027 E -118.3 128.6 5.0 0.027 0.0 HOH
 4.235
 CE
 O
6nas 3 P07737 100.0 4e-103 X-RAY
 2020-01-29 MET C:114 P:113 4.0 0.022 E -123.3 118.5 4.0 0.022 0.0
6nbe 3 P07737 100.0 4e-103 X-RAY
 2020-04-15 MET C:114 P:113 6.0 0.032 E -126.1 126.3 6.0 0.032 0.0 HOH
 5.430
 HG2
 O
6nbw 3 P07737 100.0 4e-103 X-RAY
 2020-01-29 MET C:114 P:113 6.0 0.032 E -119.7 123.3 6.0 0.032 0.0 HOH
 5.417
 HG2
 O
7p1h 3 P07737 100.0 4e-103 EM
 2021-11-17 MET C:114 P:113 7.0 0.038 E -117.9 122.0 7.0 0.038 0.0
1cjf 1 P07737 100.0 3e-102 X-RAY
 1999-07-07 MET A:113 A:113 5.0 0.027 E -124.5 123.4 5.0 0.027 0.0 HOH
 6.814
 O
 O
MET C:113 B:113 5.0 0.027 E -122.4 122.4 5.0 0.027 0.0 HOH
 5.548
 C
 O
1fik 1 P07737 100.0 3e-102 X-RAY
 1996-11-08 MET A:113 A:113 9.0 0.049 E -117.5 128.0 9.0 0.049 0.0 HOH
 6.061
 C
 O
1fil 1 P07737 100.0 3e-102 X-RAY
 1996-11-08 MET A:113 A:113 5.0 0.027 E -124.6 130.3 5.0 0.027 0.0 HOH
 5.803
 C
 O
1pfl 1 P07737 100.0 3e-102 NMR
 1995-03-31 MET A:113 A:113 16.0 0.086 E -95.6 145.8 16.0 0.086 0.0
2pav 2 P07737 100.0 3e-102 X-RAY
 2007-10-23 MET B:113 P:113 4.0 0.022 E -122.1 130.0 4.0 0.022 0.0 HOH
 3.487
 SD
 O
2pbd 2 P07737 100.0 3e-102 X-RAY
 2007-11-13 MET B:113 P:113 4.0 0.022 E -123.0 126.7 4.0 0.022 0.0 HOH
 3.498
 CE
 O
3chw 2 P07737 100.0 3e-102 X-RAY
 2008-08-19 MET B:113 P:113 5.0 0.027 E -124.4 126.5 5.0 0.027 0.0 HOH
 3.804
 CE
 O
4x25 1 P07737 99.29 4e-102 X-RAY
 2015-06-10 THR A:114 A:114 9.0 0.064 E -133.9 119.9 9.0 0.064 0.0 HOH
 5.281
 C
 O
THR B:114 B:114 11.0 0.079 E -129.5 134.1 NA NA NA
4x1m 1 P07737 99.29 9e-102 X-RAY
 2015-06-10 MET A:114 A:114 8.0 0.043 E -117.3 128.2 8.0 0.043 0.0 HOH
 3.538
 CE
 O
1awi 1 P07737 100.0 1e-101 X-RAY
 1998-10-28 MET A:112 A:113 3.0 0.016 E -127.4 122.3 3.0 0.016 0.0 HOH
 6.648
 O
 H1
MET B:112 B:113 5.0 0.027 E -117.6 120.2 5.0 0.027 0.0 HOH
 2.435
 SD
 H2
1cf0 1 P07737 100.0 1e-101 X-RAY
 1999-07-06 MET A:112 A:113 4.0 0.022 E -125.0 128.4 4.0 0.022 0.0 HOH
 3.677
 SD
 O
MET B:112 B:113 4.0 0.022 E -120.9 121.9 NA NA NA
1hlu 2 P02584 94.96 1e-98 X-RAY
 1997-10-15 MET B:114 P:113 13.0 0.07 E -123.1 122.9 13.0 0.07 0.0
1pne 1 P02584 94.96 1e-98 X-RAY
 1995-07-31 MET A:114 A:113 5.0 0.027 E -121.4 127.6 5.0 0.027 0.0 HOH
 3.907
 SD
 O
2btf 2 P02584 94.96 1e-98 X-RAY
 1994-06-22 MET B:114 P:113 4.0 0.022 E -115.5 133.2 4.0 0.022 0.0
3u4l 2 P02584 94.96 1e-98 X-RAY
 2012-04-25 MET B:114 P:113 11.0 0.059 E -117.6 128.0 11.0 0.059 0.0 HOH
 7.110
 CA
 O
3ub5 2 P02584 94.96 1e-98 X-RAY
 2012-04-25 MET B:114 P:113 5.0 0.027 E -126.3 119.1 5.0 0.027 0.0 HOH
 5.895
 CE
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p07737-f1 1 P07737 100.0 2e-103 MET A:114 A:114 6.0 0.032 E -116.3 123.4