Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 4850037 . A C CCDS11061.1:NM_005022.3:c.211Tgt>Ggt_NP_005013.1:p.71C>G Homo sapiens profilin 1 (PFN1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4x1l 1 P07737 100.0 4e-103 X-RAY
 2015-06-10 CYS A:71 A:71 2.0 0.015 E -129.0 152.8 2.0 0.015 0.0 HOH
 4.627
 O
 O
6nas 3 P07737 100.0 4e-103 X-RAY
 2020-01-29 CYS C:71 P:70 1.0 0.007 E -136.3 152.4 1.0 0.007 0.0 HOH
 4.608
 O
 O
6nbe 3 P07737 100.0 4e-103 X-RAY
 2020-04-15 CYS C:71 P:70 1.0 0.007 E -131.8 156.6 1.0 0.007 0.0 HOH
 3.029
 H
 O
6nbw 3 P07737 100.0 4e-103 X-RAY
 2020-01-29 CYS C:71 P:70 1.0 0.007 E -132.6 157.5 1.0 0.007 0.0 HOH
 4.267
 O
 O
7p1h 3 P07737 100.0 4e-103 EM
 2021-11-17 CYS C:71 P:70 3.0 0.022 E -133.7 153.8 3.0 0.022 0.0
1cjf 1 P07737 100.0 3e-102 X-RAY
 1999-07-07 CYS A:70 A:70 3.0 0.022 E -132.4 163.2 3.0 0.022 0.0 HOH
 7.980
 N
 O
CYS C:70 B:70 2.0 0.015 E -134.6 166.5 2.0 0.015 0.0 HOH
 7.753
 CB
 O
1fik 1 P07737 100.0 3e-102 X-RAY
 1996-11-08 CYS A:70 A:70 1.0 0.007 E -142.3 165.5 1.0 0.007 0.0 HOH
 6.389
 N
 O
1fil 1 P07737 100.0 3e-102 X-RAY
 1996-11-08 CYS A:70 A:70 1.0 0.007 E -135.3 158.0 1.0 0.007 0.0 HOH
 4.885
 O
 O
1pfl 1 P07737 100.0 3e-102 NMR
 1995-03-31 CYS A:70 A:70 2.0 0.015 -103.2 -170.6 2.0 0.015 0.0
2pav 2 P07737 100.0 3e-102 X-RAY
 2007-10-23 CYS B:70 P:70 0.0 0.0 E -133.8 154.8 0.0 0.0 0.0 HOH
 3.136
 O
 O
2pbd 2 P07737 100.0 3e-102 X-RAY
 2007-11-13 CYS B:70 P:70 0.0 0.0 E -135.4 152.1 0.0 0.0 0.0 HOH
 3.317
 O
 O
3chw 2 P07737 100.0 3e-102 X-RAY
 2008-08-19 CYS B:70 P:70 0.0 0.0 E -134.1 150.5 0.0 0.0 0.0 HOH
 3.484
 O
 O
4x25 1 P07737 99.29 4e-102 X-RAY
 2015-06-10 CYS A:71 A:71 6.0 0.044 E -135.7 151.2 6.0 0.044 0.0 HOH
 4.227
 O
 O
CYS B:71 B:71 10.0 0.074 E -135.9 156.3 NA NA NA
4x1m 1 P07737 99.29 9e-102 X-RAY
 2015-06-10 CYS A:71 A:71 5.0 0.037 E -132.1 159.4 5.0 0.037 0.0 HOH
 4.611
 O
 O
1awi 1 P07737 100.0 1e-101 X-RAY
 1998-10-28 CYS A:69 A:70 0.0 0.0 E -133.5 154.6 0.0 0.0 0.0 HOH
 7.544
 H
 O
CYS B:69 B:70 1.0 0.007 E -135.8 158.2 1.0 0.007 0.0 HOH
 7.376
 H
 O
1cf0 1 P07737 100.0 1e-101 X-RAY
 1999-07-06 CYS A:69 A:70 0.0 0.0 E -120.1 163.9 0.0 0.0 0.0 HOH
 7.777
 N
 O
CYS B:69 B:70 1.0 0.007 E -134.0 160.8 NA NA NA
1hlu 2 P02584 94.96 1e-98 X-RAY
 1997-10-15 CYS B:71 P:70 0.0 0.0 E -121.0 147.0 0.0 0.0 0.0
1pne 1 P02584 94.96 1e-98 X-RAY
 1995-07-31 CYS A:71 A:70 0.0 0.0 E -137.8 160.2 0.0 0.0 0.0 HOH
 4.326
 O
 O
2btf 2 P02584 94.96 1e-98 X-RAY
 1994-06-22 CYS B:71 P:70 0.0 0.0 E -140.1 132.6 0.0 0.0 0.0
3u4l 2 P02584 94.96 1e-98 X-RAY
 2012-04-25 CYS B:71 P:70 0.0 0.0 E -136.5 137.0 0.0 0.0 0.0 CA
HOH
 7.812
3.501
 O
N
 CA
O
3ub5 2 P02584 94.96 1e-98 X-RAY
 2012-04-25 CYS B:71 P:70 0.0 0.0 E -125.8 163.7 0.0 0.0 0.0 HOH
 3.421
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p07737-f1 1 P07737 100.0 2e-103 CYS A:71 A:71 1.0 0.007 E -131.9 143.1