Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 4850093 . A C CCDS11061.1:NM_005022.3:c.155gTt>gGt_NP_005013.1:p.52V>G Homo sapiens profilin 1 (PFN1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4x1l 1 P07737 100.0 4e-103 X-RAY
 2015-06-10 VAL A:52 A:52 54.0 0.348 T -103.5 9.5 54.0 0.348 0.0 HOH
 4.019
 CG2
 O
6nas 3 P07737 100.0 4e-103 X-RAY
 2020-01-29 VAL C:52 P:51 26.0 0.168 H -99.3 3.0 26.0 0.168 0.0
6nbe 3 P07737 100.0 4e-103 X-RAY
 2020-04-15 VAL C:52 P:51 37.0 0.239 H -106.1 9.8 37.0 0.239 0.0 HOH
 2.770
 HB
 O
6nbw 3 P07737 100.0 4e-103 X-RAY
 2020-01-29 VAL C:52 P:51 31.0 0.2 T -103.7 11.4 31.0 0.2 0.0 HOH
 4.961
 C
 O
7p1h 3 P07737 100.0 4e-103 EM
 2021-11-17 VAL C:52 P:51 53.0 0.342 T -103.0 11.9 53.0 0.342 0.0
1cjf 1 P07737 100.0 3e-102 X-RAY
 1999-07-07 VAL A:51 A:51 38.0 0.245 H -99.2 -0.8 38.0 0.245 0.0 HOM
HOH
 8.440
5.797
 CG2
C
 OA4
O
VAL C:51 B:51 39.0 0.252 H -118.1 6.1 39.0 0.252 0.0 HOM
HOH
 8.447
7.137
 CG1
N
 OA4
O
1fik 1 P07737 100.0 3e-102 X-RAY
 1996-11-08 VAL A:51 A:51 37.0 0.239 H -80.3 -8.3 37.0 0.239 0.0 HOH
 4.067
 CG2
 O
1fil 1 P07737 100.0 3e-102 X-RAY
 1996-11-08 VAL A:51 A:51 38.0 0.245 S -87.1 0.7 38.0 0.245 0.0 HOH
 3.963
 CG2
 O
1pfl 1 P07737 100.0 3e-102 NMR
 1995-03-31 VAL A:51 A:51 38.0 0.245 S -140.7 -6.5 38.0 0.245 0.0
2pav 2 P07737 100.0 3e-102 X-RAY
 2007-10-23 VAL B:51 P:51 36.0 0.232 H -101.2 -2.1 36.0 0.232 0.0 HOH
 2.779
 O
 O
2pbd 2 P07737 100.0 3e-102 X-RAY
 2007-11-13 VAL B:51 P:51 41.0 0.265 H -101.1 0.9 41.0 0.265 0.0 HOH
 2.784
 O
 O
3chw 2 P07737 100.0 3e-102 X-RAY
 2008-08-19 VAL B:51 P:51 34.0 0.219 H -104.8 1.0 34.0 0.219 0.0 HOH
 2.963
 O
 O
4x25 1 P07737 99.29 4e-102 X-RAY
 2015-06-10 VAL A:52 A:52 38.0 0.245 T -100.5 9.9 38.0 0.245 0.0 HOH
 5.123
 CG2
 O
VAL B:52 B:52 41.0 0.265 T -102.3 8.6 NA NA NA
4x1m 1 P07737 99.29 9e-102 X-RAY
 2015-06-10 VAL A:52 A:52 36.0 0.232 H -102.2 3.7 36.0 0.232 0.0 HOH
 4.563
 O
 O
1awi 1 P07737 100.0 1e-101 X-RAY
 1998-10-28 VAL A:50 A:51 45.0 0.29 T -92.2 20.2 45.0 0.29 0.0 HOH
 4.937
 C
 H1
VAL B:50 B:51 33.0 0.213 H -105.5 2.0 33.0 0.213 0.0 HOH
 4.174
 C
 H1
1cf0 1 P07737 100.0 1e-101 X-RAY
 1999-07-06 VAL A:50 A:51 42.0 0.271 T -96.0 17.5 42.0 0.271 0.0 HOH
 5.075
 C
 O
VAL B:50 B:51 31.0 0.2 H -107.0 -0.5 NA NA NA
1hlu 2 P02584 94.96 1e-98 X-RAY
 1997-10-15 VAL B:52 P:51 39.0 0.252 T -87.0 15.1 39.0 0.252 0.0
1pne 1 P02584 94.96 1e-98 X-RAY
 1995-07-31 VAL A:52 A:51 44.0 0.284 T -96.3 13.0 44.0 0.284 0.0 HOH
 3.934
 CG2
 O
2btf 2 P02584 94.96 1e-98 X-RAY
 1994-06-22 VAL B:52 P:51 43.0 0.277 T -131.6 18.9 43.0 0.277 0.0
3u4l 2 P02584 94.96 1e-98 X-RAY
 2012-04-25 VAL B:52 P:51 48.0 0.31 H -114.6 -17.1 48.0 0.31 0.0 HOH
 7.543
 O
 O
3ub5 2 P02584 94.96 1e-98 X-RAY
 2012-04-25 VAL B:52 P:51 38.0 0.245 H -114.4 -7.7 38.0 0.245 0.0 HOH
 7.831
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p07737-f1 1 P07737 100.0 2e-103 VAL A:52 A:52 37.0 0.239 H -94.6 1.1