Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 4851604 . G A CCDS11061.1:NM_005022.3:c.86cCc>cTc_NP_005013.1:p.29P>L Homo sapiens profilin 1 (PFN1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4x1l 1 P07737 100.0 4e-103 X-RAY
 2015-06-10 PRO A:29 A:29 23.0 0.159 -53.5 137.2 23.0 0.159 0.0 HOH
 2.557
 O
 O
6nas 3 P07737 100.0 4e-103 X-RAY
 2020-01-29 PRO C:29 P:28 42.0 0.29 -72.1 137.5 42.0 0.29 0.0
6nbe 3 P07737 100.0 4e-103 X-RAY
 2020-04-15 PRO C:29 P:28 34.0 0.234 -68.0 153.0 34.0 0.234 0.0 HOH
 3.270
 HA
 O
6nbw 3 P07737 100.0 4e-103 X-RAY
 2020-01-29 PRO C:29 P:28 32.0 0.221 -68.0 152.9 32.0 0.221 0.0 HOH
 3.361
 HA
 O
7p1h 3 P07737 100.0 4e-103 EM
 2021-11-17 PRO C:29 P:28 21.0 0.145 -67.1 154.9 21.0 0.145 0.0
1cjf 1 P07737 100.0 3e-102 X-RAY
 1999-07-07 PRO A:28 A:28 31.0 0.214 -39.3 144.3 29.0 0.2 0.014 B:None:0.014
 HOM
HOH
 4.120
4.120
 CD
C
 CA7
O
PRO C:28 B:28 32.0 0.221 -37.0 130.8 31.0 0.214 0.007 D:None:0.007
 HOM
 4.181
 CD
 CA7
1fik 1 P07737 100.0 3e-102 X-RAY
 1996-11-08 PRO A:28 A:28 27.0 0.186 -50.5 144.6 27.0 0.186 0.0 HOH
 2.980
 O
 O
1fil 1 P07737 100.0 3e-102 X-RAY
 1996-11-08 PRO A:28 A:28 24.0 0.166 -53.4 142.3 24.0 0.166 0.0 HOH
 2.801
 O
 O
1pfl 1 P07737 100.0 3e-102 NMR
 1995-03-31 PRO A:28 A:28 29.0 0.2 -76.1 157.6 29.0 0.2 0.0
2pav 2 P07737 100.0 3e-102 X-RAY
 2007-10-23 PRO B:28 P:28 29.0 0.2 -62.4 149.0 29.0 0.2 0.0 HOH
 2.647
 O
 O
2pbd 2 P07737 100.0 3e-102 X-RAY
 2007-11-13 PRO B:28 P:28 105.0 0.724 -78.4 108.0 105.0 0.724 0.0 HOH
 2.525
 O
 O
3chw 2 P07737 100.0 3e-102 X-RAY
 2008-08-19 PRO B:28 P:28 32.0 0.221 -70.3 140.7 32.0 0.221 0.0 HOH
 4.137
 CA
 O
4x25 1 P07737 99.29 4e-102 X-RAY
 2015-06-10 PRO A:29 A:29 33.0 0.228 -61.9 147.2 33.0 0.228 0.0 HOH
 3.383
 O
 O
PRO B:29 B:29 40.0 0.276 -57.8 146.1 NA NA NA
4x1m 1 P07737 99.29 9e-102 X-RAY
 2015-06-10 PRO A:29 A:29 30.0 0.207 -58.6 134.6 30.0 0.207 0.0 HOH
 2.729
 O
 O
1awi 1 P07737 100.0 1e-101 X-RAY
 1998-10-28 PRO A:27 A:28 35.0 0.241 -42.6 123.7 35.0 0.241 0.0 HOH
 6.806
 O
 H2
PRO B:27 B:28 29.0 0.2 -63.1 136.6 29.0 0.2 0.0 HOH
 8.607
 CG
 O
1cf0 1 P07737 100.0 1e-101 X-RAY
 1999-07-06 PRO A:27 A:28 33.0 0.228 -47.1 135.3 33.0 0.228 0.0 HOH
 6.644
 C
 O
PRO B:27 B:28 30.0 0.207 -56.6 131.5 NA NA NA
1hlu 2 P02584 94.96 1e-98 X-RAY
 1997-10-15 PRO B:29 P:28 40.0 0.276 -52.0 142.0 40.0 0.276 0.0
1pne 1 P02584 94.96 1e-98 X-RAY
 1995-07-31 PRO A:29 A:28 26.0 0.179 -63.9 144.3 26.0 0.179 0.0 HOH
 3.777
 CG
 O
2btf 2 P02584 94.96 1e-98 X-RAY
 1994-06-22 PRO B:29 P:28 28.0 0.193 -51.6 140.9 28.0 0.193 0.0
3u4l 2 P02584 94.96 1e-98 X-RAY
 2012-04-25 PRO B:29 P:28 22.0 0.152 -42.8 120.6 22.0 0.152 0.0 HOH
 3.098
 O
 O
3ub5 2 P02584 94.96 1e-98 X-RAY
 2012-04-25 PRO B:29 P:28 36.0 0.248 -73.8 133.1 36.0 0.248 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p07737-f1 1 P07737 100.0 2e-103 PRO A:29 A:29 37.0 0.255 -56.9 126.5