Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 56356446 . C A CCDS11604.1:NM_000250.1:c.808Gcc>Tcc_NP_000241.1:p.270A>S Homo sapiens myeloperoxidase (MPO), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bmt 1 P05164 100.0 0.0 X-RAY
2018-01-03 ALA A:270 A:270 95.0 0.826 -89.8 160.3 42.0 0.365 0.461 B:None:0.461
HOH
4.509
CA
O
5mfa 1 P05164 100.0 0.0 X-RAY
2017-04-05 ALA A:222 A:270 57.0 0.496 -81.4 151.3 57.0 0.496 0.0 TRS
HOH
6.242
2.355
HA
O
C1
O
5uzu 2 P05164 100.0 0.0 X-RAY
2017-07-26 ALA B:104 A:270 61.0 0.53 -69.4 148.6 18.0 0.157 0.373 A:W8TS31:0.374
HOH
5.766
N
O
6azp 1 P05164 100.0 0.0 X-RAY
2017-12-27 ALA A:104 A:270 55.0 0.478 -74.8 145.6 55.0 0.478 0.0 HOH
6.480
N
O
3f9p 1 P05164 100.0 1e-76 X-RAY
2009-07-14 ALA A:106 A:104 89.0 0.774 -88.4 178.5 83.0 0.722 0.052 B:P05164:0.052
ACT
9.722
N
OXT
ALA C:106 B:104 92.0 0.8 -80.1 -179.9 NA NA NA
3zs1 1 P05164 100.0 1e-76 X-RAY
2011-08-31 ALA A:106 A:104 158.0 1.0 -75.7 360.0 NA NA NA
ALA B:106 B:104 157.0 1.0 -66.1 360.0 141.0 1.0 0.0 D:P05164:0.139
PVW
ACT
HOH
8.890
9.585
9.031
O
N
N
C1
O
O
4ejx 2 P05164 100.0 1e-76 X-RAY
2013-04-10 ALA B:106 B:104 159.0 1.0 -66.2 360.0 79.0 0.687 0.313 C:P05164:0.122
A:P00450:0.609
1mhl 1 P05164 100.0 3e-72 X-RAY
1996-01-06 ALA A:106 A:104 158.0 1.0 -83.0 360.0 132.0 1.0 0.0 B:P05164:0.226
HOH
4.398
CA
O
ALA C:106 B:104 159.0 1.0 -74.7 360.0 123.0 1.0 0.0 D:P05164:0.313
HOH
3.604
CA
O
1myp 1 P05164 100.0 3e-72 X-RAY
1994-01-31 ALA A:106 A:104 157.0 1.0 -53.5 360.0 144.0 1.0 0.0 B:P05164:0.113
ALA C:106 B:104 143.0 1.0 -24.1 360.0 128.0 1.0 0.0 D:P05164:0.13
3zs0 1 P05164 100.0 3e-72 X-RAY
2011-08-31 ALA A:106 A:104 158.0 1.0 -71.7 360.0 134.0 1.0 0.0 C:P05164:0.209
ZS0
HOH
8.243
5.463
O
CA
C15
O
ALA B:106 B:104 159.0 1.0 -69.7 360.0 142.0 1.0 0.0 D:P05164:0.148
ZS0
HOH
8.496
2.691
O
O
C15
O
4c1m 1 P05164 100.0 3e-72 X-RAY
2013-11-13 ALA A:106 A:104 158.0 1.0 -50.9 360.0 NA NA NA
ALA B:106 B:104 159.0 1.0 -65.1 360.0 140.0 1.0 0.0 D:P05164:0.165
NIH
HOH
8.046
2.545
O
O
F22
O
5fiw 1 P05164 100.0 5e-70 X-RAY
2015-10-14 ALA A:104 A:104 104.0 0.904 -71.5 158.8 101.0 0.878 0.026 C:P05164:0.026
HOH
3.904
O
O
ALA B:104 NA:NA DO NA DO DO DO NA NA NA
5qj2 1 P05164 100.0 5e-70 X-RAY
2019-02-06 ALA A:104 NA:NA DO NA DO DO DO NA NA NA
ALA C:104 NA:NA DO NA DO DO DO NA NA NA
ALA E:104 NA:NA DO NA DO DO DO NA NA NA
ALA G:104 NA:NA DO NA DO DO DO NA NA NA
5qj3 1 P05164 100.0 5e-70 X-RAY
2019-02-06 ALA A:104 NA:NA DO NA DO DO DO NA NA NA
ALA C:104 NA:NA DO NA DO DO DO NA NA NA
5wdj 1 P05164 100.0 5e-70 X-RAY
2018-04-18 ALA A:104 A:104 158.0 1.0 -74.8 360.0 140.0 1.0 0.0 B:P05164:0.157
HOH
4.539
N
O
ALA C:104 NA:NA DO NA DO DO DO NA NA NA
6wxz 1 P05164 100.0 5e-70 X-RAY
2020-10-14 ALA A:104 NA:NA DO NA DO DO DO NA NA NA
ALA C:104 NA:NA DO NA DO DO DO NA NA NA
6wy0 1 P05164 100.0 5e-70 X-RAY
2020-10-14 ALA A:104 NA:NA DO NA DO DO DO NA NA NA
ALA C:104 D:104 157.0 1.0 -114.6 360.0 NA NA NA
ALA E:104 F:104 158.0 1.0 -96.2 360.0 NA NA NA
ALA G:104 NA:NA DO NA DO DO DO NA NA NA
6wy5 1 P05164 100.0 5e-70 X-RAY
2020-10-14 ALA A:104 A:104 157.0 1.0 -152.2 360.0 127.0 1.0 0.0 B:P05164:0.261
UF7
7.875
CB
C28
ALA C:104 D:104 156.0 1.0 -147.5 360.0 NA NA NA
6wy7 1 P05164 100.0 5e-70 X-RAY
2020-10-14 ALA A:104 NA:NA DO NA DO DO DO NA NA NA
ALA C:104 NA:NA DO NA DO DO DO NA NA NA
6wyd 1 P05164 100.0 5e-70 X-RAY
2020-10-14 ALA A:104 NA:NA DO NA DO DO DO NA NA NA
ALA C:104 NA:NA DO NA DO DO DO NA NA NA
ALA E:104 NA:NA DO NA DO DO DO NA NA NA
ALA G:104 NA:NA DO NA DO DO DO NA NA NA
7lae 1 P05164 100.0 5e-70 X-RAY
2021-04-21 ALA A:104 NA:NA DO NA DO DO DO NA NA NA
ALA C:104 NA:NA DO NA DO DO DO NA NA NA
7lag 1 P05164 100.0 5e-70 X-RAY
2021-04-21 ALA A:104 NA:NA DO NA DO DO DO NA NA NA
ALA C:104 NA:NA DO NA DO DO DO NA NA NA
ALA E:104 NA:NA DO NA DO DO DO NA NA NA
ALA G:104 NA:NA DO NA DO DO DO NA NA NA
7lal 1 P05164 100.0 5e-70 X-RAY
2021-04-21 ALA A:104 NA:NA DO NA DO DO DO NA NA NA
ALA C:104 D:104 156.0 1.0 -111.1 360.0 NA NA NA
7lan 1 P05164 100.0 5e-70 X-RAY
2021-04-21 ALA A:104 NA:NA DO NA DO DO DO NA NA NA
ALA C:104 D:104 157.0 1.0 -78.9 360.0 NA NA NA
ALA E:104 NA:NA DO NA DO DO DO NA NA NA
ALA G:104 NA:NA DO NA DO DO DO NA NA NA
1cxp 1 P05164 100.0 2e-69 X-RAY
2000-04-24 ALA A:104 A:104 177.0 NA -75.6 360.0 143.0 NA NA B:P05164:NA
HOH
3.116
OXT
O
ALA C:104 B:104 174.0 NA -80.5 360.0 151.0 NA NA D:P05164:NA
HOH
2.773
OXT
O
1d2v 1 P05164 100.0 2e-69 X-RAY
2000-04-24 ALA A:104 A:104 177.0 NA -67.9 360.0 145.0 NA NA B:P05164:NA
HOH
3.474
OXT
O
ALA C:104 B:104 174.0 NA -76.1 360.0 153.0 NA NA D:P05164:NA
HOH
3.072
OXT
O
1d5l 1 P05164 100.0 2e-69 X-RAY
2001-12-12 ALA A:104 A:104 176.0 NA -81.5 360.0 143.0 NA NA B:P05164:NA
HOH
2.808
OXT
O
ALA C:104 B:104 175.0 NA -79.2 360.0 150.0 NA NA D:P05164:NA
HOH
2.793
OXT
O
1d7w 1 P05164 100.0 2e-69 X-RAY
2001-12-12 ALA A:104 A:104 177.0 NA -69.3 360.0 146.0 NA NA B:P05164:NA
HOH
2.847
OXT
O
ALA C:104 B:104 178.0 NA -72.3 360.0 150.0 NA NA D:P05164:NA
HOH
2.664
OXT
O
1dnu 1 P05164 100.0 2e-69 X-RAY
2001-12-21 ALA A:104 A:104 179.0 NA -91.5 360.0 145.0 NA NA B:P05164:NA
ACY
HOH
9.956
2.836
N
OXT
OXT
O
ALA C:104 B:104 174.0 NA -85.3 360.0 149.0 NA NA D:P05164:NA
ACY
HOH
9.956
2.783
N
OXT
CH3
O
1dnw 1 P05164 100.0 2e-69 X-RAY
2001-12-21 ALA A:104 A:104 177.0 NA -78.3 360.0 145.0 NA NA B:P05164:NA
HOH
2.898
OXT
O
ALA C:104 B:104 176.0 NA -81.2 360.0 151.0 NA NA D:P05164:NA
HOH
2.588
OXT
O
4dl1 1 P05164 100.0 2e-69 X-RAY
2012-03-21 ALA A:104 A:104 171.0 NA -88.5 360.0 148.0 NA NA B:P05164:NA
0KY
HOH
4.236
4.533
CA
OXT
C1
O
ALA C:104 B:104 171.0 NA -73.9 360.0 151.0 NA NA D:P05164:NA
0KY
HOH
5.281
2.726
CA
O
C1
O
ALA E:104 E:104 175.0 NA -77.5 360.0 NA NA NA
ALA G:104 F:104 179.0 NA -85.8 360.0 NA NA NA
ALA I:104 I:104 173.0 NA -81.2 360.0 NA NA NA
ALA K:104 J:104 173.0 NA -69.2 360.0 NA NA NA
ALA M:104 M:104 173.0 NA -66.4 360.0 NA NA NA
ALA O:104 N:104 175.0 NA -72.8 360.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05164-f1 1 P05164 100.0 0.0 ALA A:270 A:270 21.0 0.183 S -60.2 -35.3