Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 56356511 . C A CCDS11604.1:NM_000250.1:c.743cGc>cTc_NP_000241.1:p.248R>L Homo sapiens myeloperoxidase (MPO), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bmt 1 P05164 100.0 0.0 X-RAY
 2018-01-03 ARG A:248 A:248 3.0 0.013 E -144.4 134.0 3.0 0.013 0.0 HOH
 4.014
 CG
 O
5mfa 1 P05164 100.0 0.0 X-RAY
 2017-04-05 ARG A:200 A:248 5.0 0.022 E -139.5 137.1 5.0 0.022 0.0 HOH
 2.121
 HH12
 O
5uzu 2 P05164 100.0 0.0 X-RAY
 2017-07-26 ARG B:82 A:248 3.0 0.013 E -138.9 125.9 3.0 0.013 0.0 HOH
 4.167
 CG
 O
6azp 1 P05164 100.0 0.0 X-RAY
 2017-12-27 ARG A:82 A:248 1.0 0.004 E -135.3 148.1 1.0 0.004 0.0 HOH
 3.171
 NH1
 O
3f9p 1 P05164 100.0 1e-76 X-RAY
 2009-07-14 ARG A:84 A:82 130.0 0.578 -131.2 141.4 4.0 0.018 0.56 B:P05164:0.56
ARG C:84 B:82 126.0 0.56 -136.1 141.3 NA NA NA
3zs1 1 P05164 100.0 1e-76 X-RAY
 2011-08-31 ARG A:84 A:82 131.0 0.582 -138.6 140.9 NA NA NA
ARG B:84 B:82 131.0 0.582 -135.5 142.6 4.0 0.018 0.564 D:P05164:0.564
 HOH
 2.940
 NH1
 O
4ejx 2 P05164 100.0 1e-76 X-RAY
 2013-04-10 ARG B:84 B:82 131.0 0.582 -135.5 142.6 2.0 0.009 0.573 C:P05164:0.573
1mhl 1 P05164 100.0 3e-72 X-RAY
 1996-01-06 ARG A:84 A:82 128.0 0.569 -148.5 143.1 4.0 0.018 0.551 B:P05164:0.551
 HOH
 4.505
 CG
 O
ARG C:84 B:82 129.0 0.573 -147.0 137.0 2.0 0.009 0.564 D:P05164:0.564
 HOH
 2.763
 NH1
 O
1myp 1 P05164 100.0 3e-72 X-RAY
 1994-01-31 ARG A:84 A:82 148.0 0.658 -151.6 141.4 9.0 0.04 0.618 B:P05164:0.618
ARG C:84 B:82 141.0 0.627 S -119.9 152.5 2.0 0.009 0.618 D:P05164:0.618
3zs0 1 P05164 100.0 3e-72 X-RAY
 2011-08-31 ARG A:84 A:82 132.0 0.587 -145.9 139.4 8.0 0.036 0.551 C:P05164:0.551
 HOH
 2.758
 NH1
 O
ARG B:84 B:82 130.0 0.578 -142.4 137.0 2.0 0.009 0.569 D:P05164:0.569
 HOH
 2.712
 NH1
 O
4c1m 1 P05164 100.0 3e-72 X-RAY
 2013-11-13 ARG A:84 A:82 128.0 0.569 -136.2 137.4 NA NA NA
ARG B:84 B:82 132.0 0.587 -143.3 140.6 6.0 0.027 0.56 D:P05164:0.56
 HOH
 2.929
 NH1
 O
5fiw 1 P05164 100.0 5e-70 X-RAY
 2015-10-14 ARG A:82 A:82 136.0 0.604 -139.5 142.9 5.0 0.022 0.582 C:P05164:0.582
 HOH
 2.817
 NH1
 O
ARG B:82 B:82 134.0 0.596 -139.0 142.2 NA NA NA
5qj2 1 P05164 100.0 5e-70 X-RAY
 2019-02-06 ARG A:82 A:82 139.0 0.618 -139.1 137.1 2.0 0.009 0.609 B:P05164:0.609
 HOH
 5.958
 N
 O
ARG C:82 D:82 124.0 0.551 -119.3 153.4 NA NA NA
ARG E:82 F:82 131.0 0.582 -144.2 147.2 NA NA NA
ARG G:82 H:82 137.0 0.609 -135.6 138.1 NA NA NA
5qj3 1 P05164 100.0 5e-70 X-RAY
 2019-02-06 ARG A:82 A:82 133.0 0.591 -144.8 145.6 3.0 0.013 0.578 B:P05164:0.578
 HOH
 4.582
 CG
 O
ARG C:82 D:82 133.0 0.591 -145.8 145.8 NA NA NA
5wdj 1 P05164 100.0 5e-70 X-RAY
 2018-04-18 ARG A:82 A:82 127.0 0.564 -136.7 136.5 3.0 0.013 0.551 B:P05164:0.551
 HOH
 4.122
 CB
 O
ARG C:82 D:82 127.0 0.564 -137.8 136.9 2.0 0.009 0.555 D:P05164:0.556
 HOH
 2.778
 NH1
 O
6wxz 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 ARG A:82 A:82 130.0 0.578 -141.3 137.7 7.0 0.031 0.547 B:P05164:0.547
 HOH
 4.690
 CG
 O
ARG C:82 D:82 132.0 0.587 -141.0 138.2 NA NA NA
6wy0 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 ARG A:82 A:82 133.0 0.591 -141.7 143.3 3.0 0.013 0.578 B:P05164:0.578
ARG C:82 D:82 137.0 0.609 -142.7 144.7 NA NA NA
ARG E:82 F:82 137.0 0.609 -141.9 143.2 NA NA NA
ARG G:82 H:82 133.0 0.591 -141.5 144.8 NA NA NA
6wy5 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 ARG A:82 A:82 131.0 0.582 -142.1 147.1 18.0 0.08 0.502 B:P05164:0.502
ARG C:82 D:82 130.0 0.578 -141.6 146.0 NA NA NA
6wy7 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 ARG A:82 A:82 135.0 0.6 -141.6 140.1 4.0 0.018 0.582 B:P05164:0.582
 HOH
 2.859
 NH1
 O
ARG C:82 D:82 128.0 0.569 -140.5 139.2 NA NA NA
6wyd 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 ARG A:82 A:82 128.0 0.569 -134.1 145.1 2.0 0.009 0.56 B:P05164:0.56
 HOH
 4.125
 CG
 O
ARG C:82 D:82 135.0 0.6 -133.5 142.7 NA NA NA
ARG E:82 F:82 133.0 0.591 -133.9 135.2 NA NA NA
ARG G:82 H:82 127.0 0.564 -127.0 138.9 NA NA NA
7lae 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 ARG A:82 A:82 136.0 0.604 -149.4 128.1 3.0 0.013 0.591 B:P05164:0.591
ARG C:82 D:82 137.0 0.609 -149.9 129.8 NA NA NA
7lag 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 ARG A:82 A:82 134.0 0.596 -142.0 136.2 4.0 0.018 0.578 B:P05164:0.578
ARG C:82 D:82 137.0 0.609 -144.3 139.6 NA NA NA
ARG E:82 F:82 134.0 0.596 -142.6 137.5 NA NA NA
ARG G:82 H:82 133.0 0.591 -143.4 139.9 NA NA NA
7lal 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 ARG A:82 A:82 34.0 NA -141.1 140.7 3.0 NA NA B:P05164:NA
ARG C:82 D:82 133.0 0.591 -139.7 143.4 NA NA NA
7lan 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 ARG A:82 A:82 134.0 0.596 -136.7 137.8 2.0 0.009 0.587 B:P05164:0.587
 HOH
 4.170
 CB
 O
ARG C:82 D:82 137.0 0.609 -136.5 141.8 NA NA NA
ARG E:82 F:82 133.0 0.591 -136.7 138.6 NA NA NA
ARG G:82 H:82 146.0 0.649 -137.4 139.5 NA NA NA
1cxp 1 P05164 100.0 2e-69 X-RAY
 2000-04-24 ARG A:82 A:82 132.0 0.587 -141.3 140.5 6.0 0.027 0.56 B:P05164:0.56
 HOH
 2.917
 NH1
 O
ARG C:82 B:82 136.0 0.604 -141.3 141.3 5.0 0.022 0.582 D:P05164:0.582
 HOH
 3.033
 NH1
 O
1d2v 1 P05164 100.0 2e-69 X-RAY
 2000-04-24 ARG A:82 A:82 126.0 0.56 -142.0 139.7 2.0 0.009 0.551 B:P05164:0.551
 HOH
 2.876
 NH2
 O
ARG C:82 B:82 138.0 0.613 -137.6 137.0 6.0 0.027 0.586 D:P05164:0.587
 HOH
 3.060
 NH1
 O
1d5l 1 P05164 100.0 2e-69 X-RAY
 2001-12-12 ARG A:82 A:82 128.0 0.569 -138.5 140.4 3.0 0.013 0.556 B:P05164:0.556
 HOH
 2.783
 NH1
 O
ARG C:82 B:82 132.0 0.587 -140.5 140.2 5.0 0.022 0.565 D:P05164:0.564
 HOH
 3.099
 NH1
 O
1d7w 1 P05164 100.0 2e-69 X-RAY
 2001-12-12 ARG A:82 A:82 135.0 0.6 -139.1 138.6 4.0 0.018 0.582 B:P05164:0.582
 SO4
HOH
 4.586
2.808
 NH1
NH1
 O1
O
ARG C:82 B:82 134.0 0.596 -141.5 144.1 9.0 0.04 0.556 D:P05164:0.556
 SO4
HOH
 4.745
3.453
 NH1
NH2
 O4
O
1dnu 1 P05164 100.0 2e-69 X-RAY
 2001-12-21 ARG A:82 A:82 128.0 0.569 -140.5 141.5 3.0 0.013 0.556 B:P05164:0.556
 HOH
 2.893
 NH2
 O
ARG C:82 B:82 133.0 0.591 -140.7 139.7 5.0 0.022 0.569 D:P05164:0.569
 HOH
 2.999
 NH2
 O
1dnw 1 P05164 100.0 2e-69 X-RAY
 2001-12-21 ARG A:82 A:82 128.0 0.569 -141.4 135.2 2.0 0.009 0.56 B:P05164:0.56
 HOH
 2.988
 NH2
 O
ARG C:82 B:82 131.0 0.582 -144.4 135.9 5.0 0.022 0.56 D:P05164:0.56
 HOH
 2.822
 NH2
 O
4dl1 1 P05164 100.0 2e-69 X-RAY
 2012-03-21 ARG A:82 A:82 132.0 0.587 -134.4 139.4 5.0 0.022 0.565 B:P05164:0.564
 HOH
 3.077
 NH1
 O
ARG C:82 B:82 130.0 0.578 -127.0 135.7 7.0 0.031 0.547 D:P05164:0.547
 HOH
 2.754
 NH1
 O
ARG E:82 E:82 129.0 0.573 -138.8 137.5 NA NA NA
ARG G:82 F:82 135.0 0.6 -134.7 138.0 NA NA NA
ARG I:82 I:82 136.0 0.604 -131.6 144.3 NA NA NA
ARG K:82 J:82 132.0 0.587 -137.5 136.3 NA NA NA
ARG M:82 M:82 125.0 0.556 -139.9 135.8 NA NA NA
ARG O:82 N:82 131.0 0.582 -134.2 138.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05164-f1 1 P05164 100.0 0.0 ARG A:248 A:248 2.0 0.009 E -132.7 131.5