Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 56356533 . G A CCDS11604.1:NM_000250.1:c.721Cag>Tag_NP_000241.1:p.241Q>* Homo sapiens myeloperoxidase (MPO), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bmt 1 P05164 100.0 0.0 X-RAY
 2018-01-03 GLN A:241 A:241 110.0 0.611 G -95.3 15.5 110.0 0.611 0.0 HOH
 7.387
 N
 O
5mfa 1 P05164 100.0 0.0 X-RAY
 2017-04-05 GLN A:193 A:241 114.0 0.633 G -90.7 -1.6 114.0 0.633 0.0 HOH
 1.723
 HE22
 O
5uzu 2 P05164 100.0 0.0 X-RAY
 2017-07-26 GLN B:75 A:241 119.0 0.661 G -84.9 9.6 119.0 0.661 0.0 HOH
 2.391
 OE1
 O
6azp 1 P05164 100.0 0.0 X-RAY
 2017-12-27 GLN A:75 A:241 117.0 0.65 G -93.5 -2.5 117.0 0.65 0.0 HOH
 2.569
 OE1
 O
3f9p 1 P05164 100.0 1e-76 X-RAY
 2009-07-14 GLN A:77 A:75 138.0 0.767 G -94.5 3.4 118.0 0.656 0.111 B:P05164:0.111
GLN C:77 B:75 137.0 0.761 G -101.6 4.3 NA NA NA
3zs1 1 P05164 100.0 1e-76 X-RAY
 2011-08-31 GLN A:77 A:75 128.0 0.711 G -85.7 -2.3 NA NA NA
GLN B:77 B:75 133.0 0.739 G -83.6 5.4 110.0 0.611 0.128 D:P05164:0.128
 HOH
 5.347
 N
 O
4ejx 2 P05164 100.0 1e-76 X-RAY
 2013-04-10 GLN B:77 B:75 130.0 0.722 G -83.6 5.4 108.0 0.6 0.122 C:P05164:0.122
1mhl 1 P05164 100.0 3e-72 X-RAY
 1996-01-06 GLN A:77 A:75 125.0 0.694 G -95.1 0.6 107.0 0.594 0.1 B:P05164:0.1
 HOH
 5.090
 O
 O
GLN C:77 B:75 129.0 0.717 G -99.5 6.1 100.0 0.556 0.161 D:P05164:0.161
 HOH
 5.016
 O
 O
1myp 1 P05164 100.0 3e-72 X-RAY
 1994-01-31 GLN A:77 A:75 135.0 0.75 G -102.6 41.5 119.0 0.661 0.089 B:P05164:0.089
GLN C:77 B:75 131.0 0.728 S -93.0 2.7 108.0 0.6 0.128 D:P05164:0.128
3zs0 1 P05164 100.0 3e-72 X-RAY
 2011-08-31 GLN A:77 A:75 128.0 0.711 G -91.5 -6.7 109.0 0.606 0.105 C:P05164:0.106
 SO4
HOH
 8.412
4.783
 N
O
 O2
O
GLN B:77 B:75 130.0 0.722 G -90.3 -2.7 109.0 0.606 0.116 D:P05164:0.117
 SO4
HOH
 8.818
2.812
 N
NE2
 O4
O
4c1m 1 P05164 100.0 3e-72 X-RAY
 2013-11-13 GLN A:77 A:75 130.0 0.722 G -90.3 -2.7 NA NA NA
GLN B:77 B:75 135.0 0.75 G -84.6 -1.2 114.0 0.633 0.117 D:P05164:0.117
 SO4
HOH
 8.056
3.675
 N
CB
 O3
O
5fiw 1 P05164 100.0 5e-70 X-RAY
 2015-10-14 GLN A:75 A:75 138.0 0.767 G -81.7 -8.1 113.0 0.628 0.139 C:P05164:0.139
 HOH
 2.466
 OE1
 O
GLN B:75 B:75 129.0 0.717 G -82.4 -8.6 NA NA NA
5qj2 1 P05164 100.0 5e-70 X-RAY
 2019-02-06 GLN A:75 A:75 138.0 0.767 G -75.5 -12.9 115.0 0.639 0.128 B:P05164:0.128
GLN C:75 D:75 141.0 0.783 G -136.7 -25.1 NA NA NA
GLN E:75 F:75 141.0 0.783 G -75.8 -3.4 NA NA NA
GLN G:75 H:75 132.0 0.733 T -53.0 -31.2 NA NA NA
5qj3 1 P05164 100.0 5e-70 X-RAY
 2019-02-06 GLN A:75 A:75 132.0 0.733 G -93.7 2.3 115.0 0.639 0.094 B:P05164:0.094
 HOH
 7.708
 NE2
 O
GLN C:75 D:75 144.0 0.8 G -80.1 -2.0 NA NA NA
5wdj 1 P05164 100.0 5e-70 X-RAY
 2018-04-18 GLN A:75 A:75 118.0 0.656 G -78.5 -10.8 98.0 0.544 0.112 B:P05164:0.111
 HOH
 4.676
 O
 O
GLN C:75 D:75 127.0 0.706 G -90.8 -2.7 105.0 0.583 0.123 D:P05164:0.122
 HOH
 2.878
 OE1
 O
6wxz 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 GLN A:75 A:75 135.0 0.75 G -90.3 9.3 118.0 0.656 0.094 B:P05164:0.094
 HOH
 4.099
 OE1
 O
GLN C:75 D:75 147.0 0.817 G -88.3 8.4 NA NA NA
6wy0 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 GLN A:75 A:75 121.0 0.672 G -87.0 -15.4 103.0 0.572 0.1 B:P05164:0.1
 HOH
 8.452
 CG
 O
GLN C:75 D:75 132.0 0.733 G -87.7 -14.2 NA NA NA
GLN E:75 F:75 117.0 0.65 G -88.9 -14.7 NA NA NA
GLN G:75 H:75 127.0 0.706 G -109.1 -13.5 NA NA NA
6wy5 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 GLN A:75 A:75 123.0 0.683 G -84.0 14.1 109.0 0.606 0.077 B:P05164:0.078
GLN C:75 D:75 141.0 0.783 G -92.8 13.3 NA NA NA
6wy7 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 GLN A:75 A:75 125.0 0.694 G -81.7 -13.9 104.0 0.578 0.116 B:P05164:0.117
 HOH
 2.905
 OE1
 O
GLN C:75 D:75 126.0 0.7 G -81.4 -14.8 NA NA NA
6wyd 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 GLN A:75 A:75 137.0 0.761 G -75.0 -15.3 116.0 0.644 0.117 B:P05164:0.117
 HOH
 4.662
 O
 O
GLN C:75 D:75 133.0 0.739 G -66.1 -10.6 NA NA NA
GLN E:75 F:75 133.0 0.739 G -91.4 -14.8 NA NA NA
GLN G:75 H:75 77.0 NA G -70.6 -0.5 NA NA NA
7lae 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 GLN A:75 A:75 131.0 0.728 G -70.3 -10.8 118.0 0.656 0.072 B:P05164:0.072
GLN C:75 D:75 64.0 NA T -68.2 -23.2 NA NA NA
7lag 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 GLN A:75 A:75 129.0 0.717 G -80.2 -15.6 113.0 0.628 0.089 B:P05164:0.089
GLN C:75 D:75 125.0 0.694 G -82.0 -13.4 NA NA NA
GLN E:75 F:75 127.0 0.706 G -81.6 -14.5 NA NA NA
GLN G:75 H:75 133.0 0.739 G -82.2 -12.6 NA NA NA
7lal 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 GLN A:75 A:75 143.0 0.794 G -69.6 19.0 128.0 0.711 0.083 B:P05164:0.083
GLN C:75 D:75 148.0 0.822 G -58.2 -9.2 NA NA NA
7lan 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 GLN A:75 A:75 129.0 0.717 G -80.3 -14.1 110.0 0.611 0.106 B:P05164:0.106
 HOH
 3.095
 O
 O
GLN C:75 D:75 126.0 0.7 G -79.6 -16.7 NA NA NA
GLN E:75 F:75 127.0 0.706 G -80.1 -15.3 NA NA NA
GLN G:75 H:75 61.0 NA G -79.3 -16.2 NA NA NA
1cxp 1 P05164 100.0 2e-69 X-RAY
 2000-04-24 GLN A:75 A:75 130.0 0.722 G -88.3 -4.6 108.0 0.6 0.122 B:P05164:0.122
 SO4
HOH
 8.362
2.839
 N
O
 O2
O
GLN C:75 B:75 131.0 0.728 G -83.9 -10.3 110.0 0.611 0.117 D:P05164:0.117
 SO4
HOH
 8.221
2.849
 N
NE2
 O2
O
1d2v 1 P05164 100.0 2e-69 X-RAY
 2000-04-24 GLN A:75 A:75 127.0 0.706 G -86.9 -8.7 107.0 0.594 0.112 B:P05164:0.111
 SO4
HOH
 8.150
2.906
 N
OE1
 O2
O
GLN C:75 B:75 132.0 0.733 G -82.2 -13.6 107.0 0.594 0.139 D:P05164:0.139
 SO4
HOH
 8.005
2.549
 N
NE2
 O2
O
1d5l 1 P05164 100.0 2e-69 X-RAY
 2001-12-12 GLN A:75 A:75 125.0 0.694 G -88.0 -6.1 103.0 0.572 0.122 B:P05164:0.122
 SO4
HOH
 8.256
2.799
 N
OE1
 O2
O
GLN C:75 B:75 128.0 0.711 G -84.6 -6.8 103.0 0.572 0.139 D:P05164:0.139
 SO4
HOH
 8.329
2.637
 N
OE1
 O2
O
1d7w 1 P05164 100.0 2e-69 X-RAY
 2001-12-12 GLN A:75 A:75 125.0 0.694 G -92.5 -9.2 105.0 0.583 0.111 B:P05164:0.111
 SO4
HOH
 8.235
2.936
 N
OE1
 O2
O
GLN C:75 B:75 134.0 0.744 G -84.6 -1.6 114.0 0.633 0.111 D:P05164:0.111
 SO4
HOH
 8.959
2.609
 N
NE2
 O4
O
1dnu 1 P05164 100.0 2e-69 X-RAY
 2001-12-21 GLN A:75 A:75 128.0 0.711 G -91.0 -4.1 108.0 0.6 0.111 B:P05164:0.111
 SO4
HOH
 8.241
2.969
 N
O
 O2
O
GLN C:75 B:75 131.0 0.728 G -89.4 -8.4 105.0 0.583 0.145 D:P05164:0.144
 SO4
HOH
 8.618
2.693
 N
OE1
 O2
O
1dnw 1 P05164 100.0 2e-69 X-RAY
 2001-12-21 GLN A:75 A:75 126.0 0.7 G -90.9 -10.3 105.0 0.583 0.117 B:P05164:0.117
 SO4
HOH
 8.219
2.929
 N
OE1
 O2
O
GLN C:75 B:75 127.0 0.706 G -85.2 -6.0 101.0 0.561 0.145 D:P05164:0.144
 SO4
HOH
 8.186
2.532
 N
OE1
 O2
O
4dl1 1 P05164 100.0 2e-69 X-RAY
 2012-03-21 GLN A:75 A:75 135.0 0.75 G -94.0 -7.8 111.0 0.617 0.133 B:P05164:0.133
 HOH
 2.736
 OE1
 O
GLN C:75 B:75 125.0 0.694 G -84.0 -11.8 108.0 0.6 0.094 D:P05164:0.094
 HOH
 4.421
 O
 O
GLN E:75 E:75 134.0 0.744 G -97.6 3.2 NA NA NA
GLN G:75 F:75 121.0 0.672 G -94.5 -0.1 NA NA NA
GLN I:75 I:75 132.0 0.733 G -103.2 -3.4 NA NA NA
GLN K:75 J:75 126.0 0.7 G -84.0 -4.3 NA NA NA
GLN M:75 M:75 141.0 0.783 G -110.8 14.0 NA NA NA
GLN O:75 N:75 137.0 0.761 G -92.8 -16.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05164-f1 1 P05164 100.0 0.0 GLN A:241 A:241 98.0 0.544 G -86.4 -1.4