Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 56356705 . A C CCDS11604.1:NM_000250.1:c.631Tac>Gac_NP_000241.1:p.211Y>D Homo sapiens myeloperoxidase (MPO), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bmt 1 P05164 100.0 0.0 X-RAY
 2018-01-03 TYR A:211 A:211 35.0 0.152 T -58.0 137.0 35.0 0.152 0.0 HOH
 2.970
 N
 O
5mfa 1 P05164 100.0 0.0 X-RAY
 2017-04-05 TYR A:163 A:211 34.0 0.148 T -58.0 136.0 34.0 0.148 0.0 HOH
 1.851
 HH
 O
5uzu 2 P05164 100.0 0.0 X-RAY
 2017-07-26 TYR B:45 A:211 38.0 0.165 T -58.7 139.8 38.0 0.165 0.0 HOH
 3.047
 N
 O
6azp 1 P05164 100.0 0.0 X-RAY
 2017-12-27 TYR A:45 A:211 35.0 0.152 T -54.6 140.3 35.0 0.152 0.0 HOH
 2.711
 OH
 O
3f9p 1 P05164 100.0 1e-76 X-RAY
 2009-07-14 TYR A:47 A:45 67.0 0.291 T -71.3 130.7 38.0 0.165 0.126 B:P05164:0.126
TYR C:47 B:45 70.0 0.304 T -73.7 129.6 NA NA NA
3zs1 1 P05164 100.0 1e-76 X-RAY
 2011-08-31 TYR A:47 A:45 65.0 0.283 T -67.5 126.2 NA NA NA
TYR B:47 B:45 74.0 0.322 T -61.8 134.9 39.0 0.17 0.152 D:P05164:0.152
 HOH
 2.833
 N
 O
4ejx 2 P05164 100.0 1e-76 X-RAY
 2013-04-10 TYR B:47 B:45 73.0 0.317 T -61.8 134.9 39.0 0.17 0.147 C:P05164:0.148
1mhl 1 P05164 100.0 3e-72 X-RAY
 1996-01-06 TYR A:47 A:45 68.0 0.296 T -59.7 132.7 16.0 0.07 0.226 B:P05164:0.143
C:P05164:0.078
 HOH
 2.808
 O
 O
TYR C:47 B:45 60.0 0.261 T -62.8 131.1 13.0 0.057 0.204 D:P05164:0.139
A:P05164:0.065
 HOH
 2.872
 O
 O
1myp 1 P05164 100.0 3e-72 X-RAY
 1994-01-31 TYR A:47 A:45 47.0 0.204 T -45.9 -38.0 14.0 0.061 0.143 B:P05164:0.065
C:P05164:0.078
TYR C:47 B:45 68.0 0.296 S -66.3 149.0 13.0 0.057 0.239 D:P05164:0.109
A:P05164:0.126
3zs0 1 P05164 100.0 3e-72 X-RAY
 2011-08-31 TYR A:47 A:45 70.0 0.304 T -62.4 132.5 19.0 0.083 0.221 B:P05164:0.091
C:P05164:0.13
 HOH
 2.704
 O
 O
TYR B:47 B:45 68.0 0.296 T -59.3 133.9 20.0 0.087 0.209 A:P05164:0.083
D:P05164:0.126
 HOH
 2.630
 OH
 O
4c1m 1 P05164 100.0 3e-72 X-RAY
 2013-11-13 TYR A:47 A:45 69.0 0.3 T -61.7 134.2 NA NA NA
TYR B:47 B:45 69.0 0.3 T -59.4 142.3 40.0 0.174 0.126 D:P05164:0.126
 HOH
 2.962
 N
 O
5fiw 1 P05164 100.0 5e-70 X-RAY
 2015-10-14 TYR A:45 A:45 66.0 0.287 T -55.3 136.1 37.0 0.161 0.126 C:P05164:0.126
 HOH
 2.998
 O
 O
TYR B:45 B:45 68.0 0.296 T -55.3 137.1 NA NA NA
5qj2 1 P05164 100.0 5e-70 X-RAY
 2019-02-06 TYR A:45 A:45 71.0 0.309 T -65.1 129.7 43.0 0.187 0.122 B:P05164:0.122
 HOH
 7.907
 OH
 O
TYR C:45 D:45 75.0 0.326 T -62.6 140.6 NA NA NA
TYR E:45 F:45 72.0 0.313 T -68.6 135.7 NA NA NA
TYR G:45 H:45 66.0 0.287 T -67.4 120.4 NA NA NA
5qj3 1 P05164 100.0 5e-70 X-RAY
 2019-02-06 TYR A:45 A:45 69.0 0.3 T -65.8 133.8 40.0 0.174 0.126 B:P05164:0.126
 HOH
 2.843
 N
 O
TYR C:45 D:45 69.0 0.3 T -66.5 134.6 NA NA NA
5wdj 1 P05164 100.0 5e-70 X-RAY
 2018-04-18 TYR A:45 A:45 69.0 0.3 T -59.1 133.5 16.0 0.07 0.23 B:P05164:0.143
C:P05164:0.087
 HOH
 2.717
 O
 O
TYR C:45 D:45 69.0 0.3 T -56.2 132.8 16.0 0.07 0.23 D:P05164:0.135
A:P05164:0.096
 HOH
 2.914
 O
 O
6wxz 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 TYR A:45 A:45 72.0 0.313 T -64.0 132.9 42.0 0.183 0.13 B:P05164:0.13
 HOH
 2.629
 OH
 O
TYR C:45 D:45 70.0 0.304 T -65.0 133.0 NA NA NA
6wy0 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 TYR A:45 A:45 73.0 0.317 T -66.8 128.1 43.0 0.187 0.13 B:P05164:0.13
 HOH
 2.864
 N
 O
TYR C:45 D:45 73.0 0.317 T -64.5 126.5 NA NA NA
TYR E:45 F:45 73.0 0.317 T -65.4 127.3 NA NA NA
TYR G:45 H:45 70.0 0.304 T -65.6 128.0 NA NA NA
6wy5 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 TYR A:45 A:45 74.0 0.322 T -58.8 135.7 44.0 0.191 0.131 B:P05164:0.13
TYR C:45 D:45 73.0 0.317 T -58.9 135.2 NA NA NA
6wy7 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 TYR A:45 A:45 70.0 0.304 T -63.2 135.0 39.0 0.17 0.134 B:P05164:0.135
 HOH
 2.964
 OH
 O
TYR C:45 D:45 66.0 0.287 T -61.1 134.0 NA NA NA
6wyd 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 TYR A:45 A:45 69.0 0.3 T -62.3 136.7 41.0 0.178 0.122 B:P05164:0.122
 HOH
 3.426
 N
 O
TYR C:45 D:45 64.0 0.278 T -60.2 135.0 NA NA NA
TYR E:45 F:45 70.0 0.304 T -63.0 123.0 NA NA NA
TYR G:45 H:45 72.0 0.313 T -63.7 138.9 NA NA NA
7lae 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 TYR A:45 A:45 71.0 0.309 T -64.5 128.8 45.0 0.196 0.113 B:P05164:0.113
TYR C:45 D:45 71.0 0.309 T -63.7 128.9 NA NA NA
7lag 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 TYR A:45 A:45 71.0 0.309 T -63.2 125.3 43.0 0.187 0.122 B:P05164:0.122
TYR C:45 D:45 75.0 0.326 T -63.7 127.9 NA NA NA
TYR E:45 F:45 71.0 0.309 T -63.0 125.1 NA NA NA
TYR G:45 H:45 69.0 0.3 T -64.1 126.1 NA NA NA
7lal 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 TYR A:45 A:45 69.0 0.3 T -64.6 131.6 41.0 0.178 0.122 B:P05164:0.122
TYR C:45 D:45 70.0 0.304 T -64.0 131.4 NA NA NA
7lan 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 TYR A:45 A:45 70.0 0.304 T -61.6 134.6 40.0 0.174 0.13 B:P05164:0.13
 HOH
 3.077
 N
 O
TYR C:45 D:45 66.0 0.287 T -62.0 134.7 NA NA NA
TYR E:45 F:45 69.0 0.3 T -59.4 134.2 NA NA NA
TYR G:45 H:45 69.0 0.3 T -62.9 132.9 NA NA NA
1cxp 1 P05164 100.0 2e-69 X-RAY
 2000-04-24 TYR A:45 A:45 71.0 0.309 T -59.3 132.7 18.0 0.078 0.231 B:P05164:0.139
C:P05164:0.096
 HOH
 2.542
 OH
 O
TYR C:45 B:45 65.0 0.283 T -56.3 136.8 17.0 0.074 0.209 D:P05164:0.126
A:P05164:0.083
 HOH
 2.623
 OH
 O
1d2v 1 P05164 100.0 2e-69 X-RAY
 2000-04-24 TYR A:45 A:45 68.0 0.296 T -61.7 134.3 17.0 0.074 0.222 B:P05164:0.126
C:P05164:0.096
 HOH
 2.640
 OH
 O
TYR C:45 B:45 68.0 0.296 T -59.8 138.2 20.0 0.087 0.209 D:P05164:0.126
A:P05164:0.083
 HOH
 2.662
 OH
 O
1d5l 1 P05164 100.0 2e-69 X-RAY
 2001-12-12 TYR A:45 A:45 69.0 0.3 T -61.1 131.7 18.0 0.078 0.222 B:P05164:0.13
C:P05164:0.087
 HOH
 2.420
 OH
 O
TYR C:45 B:45 69.0 0.3 T -58.7 135.2 18.0 0.078 0.222 D:P05164:0.13
A:P05164:0.091
 HOH
 2.515
 OH
 O
1d7w 1 P05164 100.0 2e-69 X-RAY
 2001-12-12 TYR A:45 A:45 73.0 0.317 T -61.5 133.9 20.0 0.087 0.23 B:P05164:0.139
C:P05164:0.091
 ACT
ACT
HOH
 9.989
5.402
2.453
 OH
OH
OH
 O
OXT
O
TYR C:45 B:45 70.0 0.304 T -56.3 132.8 20.0 0.087 0.217 A:P05164:0.078
D:P05164:0.139
 HOH
 2.885
 OH
 O
1dnu 1 P05164 100.0 2e-69 X-RAY
 2001-12-21 TYR A:45 A:45 70.0 0.304 T -61.0 134.0 19.0 0.083 0.221 B:P05164:0.135
C:P05164:0.091
 HOH
 2.573
 OH
 O
TYR C:45 B:45 68.0 0.296 T -61.5 137.0 18.0 0.078 0.218 D:P05164:0.13
A:P05164:0.087
 HOH
 2.756
 OH
 O
1dnw 1 P05164 100.0 2e-69 X-RAY
 2001-12-21 TYR A:45 A:45 71.0 0.309 T -63.3 128.8 19.0 0.083 0.226 B:P05164:0.135
C:P05164:0.091
 HOH
 2.588
 OH
 O
TYR C:45 B:45 70.0 0.304 T -64.0 132.8 19.0 0.083 0.221 A:P05164:0.091
D:P05164:0.135
 HOH
 2.680
 OH
 O
4dl1 1 P05164 100.0 2e-69 X-RAY
 2012-03-21 TYR A:45 A:45 69.0 0.3 T -53.2 127.1 19.0 0.083 0.217 B:P05164:0.126
C:P05164:0.091
 HOH
 2.452
 OH
 O
TYR C:45 B:45 69.0 0.3 T -55.5 128.5 18.0 0.078 0.222 D:P05164:0.126
A:P05164:0.096
 HOH
 3.045
 N
 O
TYR E:45 E:45 70.0 0.304 T -61.7 132.8 NA NA NA
TYR G:45 F:45 68.0 0.296 T -58.2 130.0 NA NA NA
TYR I:45 I:45 69.0 0.3 T -61.8 132.9 NA NA NA
TYR K:45 J:45 70.0 0.304 T -59.3 135.2 NA NA NA
TYR M:45 M:45 70.0 0.304 T -58.4 130.8 NA NA NA
TYR O:45 N:45 71.0 0.309 T -60.8 134.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05164-f1 1 P05164 100.0 0.0 TYR A:211 A:211 42.0 0.183 T -56.4 132.6