Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr17 | 56356732 | . | C | A | CCDS11604.1:NM_000250.1:c.604Gag>Tag_NP_000241.1:p.202E>* | Homo sapiens myeloperoxidase (MPO), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6bmt | 1 | P05164 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | GLU | A:202 | A:202 | 68.0 | 0.358 | -126.5 | 100.0 | 68.0 | 0.358 | 0.0 |
CL HOH |
9.075 2.570 |
N OE2 |
CL O |
|||
| 5mfa | 1 | P05164 | 100.0 | 0.0 |
X-RAY |
2017-04-05 | GLU | A:154 | A:202 | 57.0 | 0.3 | -123.4 | 103.3 | 57.0 | 0.3 | 0.0 |
CL HOH |
8.446 2.546 |
H OE1 |
CL O |
|||
| 5uzu | 2 | P05164 | 100.0 | 0.0 |
X-RAY |
2017-07-26 | GLU | B:36 | A:202 | 68.0 | 0.358 | -122.9 | 104.1 | 68.0 | 0.358 | 0.0 |
CL HOH |
8.723 2.998 |
N O |
CL O |
|||
| 6azp | 1 | P05164 | 100.0 | 0.0 |
X-RAY |
2017-12-27 | GLU | A:36 | A:202 | 62.0 | 0.326 | -133.6 | 101.9 | 62.0 | 0.326 | 0.0 |
HOH |
2.243 |
OE1 |
O |
|||
| 3f9p | 1 | P05164 | 100.0 | 1e-76 |
X-RAY |
2009-07-14 | GLU | A:38 | A:36 | 122.0 | 0.642 | -112.4 | 108.5 | 66.0 | 0.347 | 0.295 |
B:P05164:0.295 |
CL |
9.067 |
N |
CL |
||
| GLU | C:38 | B:36 | 121.0 | 0.637 | -111.5 | 103.9 | NA | NA | NA | ||||||||||||||
| 3zs1 | 1 | P05164 | 100.0 | 1e-76 |
X-RAY |
2011-08-31 | GLU | A:38 | A:36 | 122.0 | 0.642 | -125.1 | 106.0 | NA | NA | NA | |||||||
| GLU | B:38 | B:36 | 133.0 | 0.7 | -114.5 | 99.8 | 76.0 | 0.4 | 0.3 |
D:P05164:0.3 |
CL HOH |
8.913 2.862 |
N OE2 |
CL O |
|||||||||
| 4ejx | 2 | P05164 | 100.0 | 1e-76 |
X-RAY |
2013-04-10 | GLU | B:38 | B:36 | 131.0 | 0.689 | -114.4 | 99.8 | 75.0 | 0.395 | 0.294 |
C:P05164:0.295 |
||||||
| 1mhl | 1 | P05164 | 100.0 | 3e-72 |
X-RAY |
1996-01-06 | GLU | A:38 | A:36 | 120.0 | 0.632 | -119.7 | 108.3 | 5.0 | 0.026 | 0.606 |
B:P05164:0.3 C:P05164:0.358 |
NAG CL HOH |
9.733 8.969 2.620 |
OE2 N OE1 |
C8 CL O |
||
| GLU | C:38 | B:36 | 118.0 | 0.621 | -126.6 | 104.8 | 6.0 | 0.032 | 0.589 |
D:P05164:0.289 A:P05164:0.358 |
NAG CL HOH |
9.491 9.081 2.699 |
OE2 N OE1 |
C8 CL O |
|||||||||
| 1myp | 1 | P05164 | 100.0 | 3e-72 |
X-RAY |
1994-01-31 | GLU | A:38 | A:36 | 130.0 | 0.684 | -109.9 | 99.9 | 13.0 | 0.068 | 0.616 |
B:P05164:0.289 C:P05164:0.363 |
NAG |
9.570 |
OE2 |
C8 |
||
| GLU | C:38 | B:36 | 116.0 | 0.611 | -126.9 | 80.2 | 7.0 | 0.037 | 0.574 |
D:P05164:0.263 A:P05164:0.358 |
NAG |
9.253 |
OE2 |
C8 |
|||||||||
| 3zs0 | 1 | P05164 | 100.0 | 3e-72 |
X-RAY |
2011-08-31 | GLU | A:38 | A:36 | 127.0 | 0.668 | -121.6 | 103.0 | 10.0 | 0.053 | 0.615 |
B:P05164:0.384 C:P05164:0.284 |
NAG CL HOH |
9.500 9.071 2.656 |
OE2 N OE2 |
C8 CL O |
||
| GLU | B:38 | B:36 | 129.0 | 0.679 | -122.8 | 104.9 | 10.0 | 0.053 | 0.626 |
A:P05164:0.389 D:P05164:0.295 |
NAG CL HOH |
9.438 9.041 2.579 |
OE2 N OE1 |
O7 CL O |
|||||||||
| 4c1m | 1 | P05164 | 100.0 | 3e-72 |
X-RAY |
2013-11-13 | GLU | A:38 | A:36 | 131.0 | 0.689 | -123.3 | 97.0 | NA | NA | NA | |||||||
| GLU | B:38 | B:36 | 123.0 | 0.647 | -127.2 | 99.1 | 66.0 | 0.347 | 0.3 |
D:P05164:0.3 |
CL HOH |
9.015 2.504 |
N OE1 |
CL O |
|||||||||
| 5fiw | 1 | P05164 | 100.0 | 5e-70 |
X-RAY |
2015-10-14 | GLU | A:36 | A:36 | 126.0 | 0.663 | -125.3 | 102.8 | 71.0 | 0.374 | 0.289 |
C:P05164:0.289 |
CL HOH |
9.082 2.619 |
N OE1 |
CL O |
||
| GLU | B:36 | B:36 | 123.0 | 0.647 | -123.8 | 103.5 | NA | NA | NA | ||||||||||||||
| 5qj2 | 1 | P05164 | 100.0 | 5e-70 |
X-RAY |
2019-02-06 | GLU | A:36 | A:36 | 120.0 | 0.632 | -126.0 | 109.1 | 66.0 | 0.347 | 0.285 |
B:P05164:0.284 |
NAG |
9.010 |
OE2 |
C8 |
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| GLU | C:36 | D:36 | 140.0 | 0.737 | -107.7 | 87.4 | NA | NA | NA | ||||||||||||||
| GLU | E:36 | F:36 | 138.0 | 0.726 | -119.0 | 84.0 | NA | NA | NA | ||||||||||||||
| GLU | G:36 | H:36 | 118.0 | 0.621 | -143.6 | 110.7 | NA | NA | NA | ||||||||||||||
| 5qj3 | 1 | P05164 | 100.0 | 5e-70 |
X-RAY |
2019-02-06 | GLU | A:36 | A:36 | 122.0 | 0.642 | -121.5 | 99.1 | 72.0 | 0.379 | 0.263 |
B:P05164:0.263 |
CL HOH |
9.275 2.719 |
N O |
CL O |
||
| GLU | C:36 | D:36 | 122.0 | 0.642 | -120.3 | 99.1 | NA | NA | NA | ||||||||||||||
| 5wdj | 1 | P05164 | 100.0 | 5e-70 |
X-RAY |
2018-04-18 | GLU | A:36 | A:36 | 123.0 | 0.647 | -125.6 | 105.7 | 8.0 | 0.042 | 0.605 |
B:P05164:0.289 C:P05164:0.379 |
NAG CL HOH |
9.642 9.291 2.593 |
OE2 N OE1 |
C8 CL O |
||
| GLU | C:36 | D:36 | 122.0 | 0.642 | -123.4 | 104.7 | 8.0 | 0.042 | 0.6 |
D:P05164:0.279 A:P05164:0.379 |
NAG CL HOH |
9.605 9.141 2.274 |
OE2 N OE1 |
C8 CL O |
|||||||||
| 6wxz | 1 | P05164 | 100.0 | 5e-70 |
X-RAY |
2020-10-14 | GLU | A:36 | A:36 | 123.0 | 0.647 | -122.7 | 101.8 | 71.0 | 0.374 | 0.273 |
B:P05164:0.274 |
CL NAG HOH |
9.137 9.250 2.671 |
N OE2 OE1 |
CL C8 O |
||
| GLU | C:36 | D:36 | 128.0 | 0.674 | -121.8 | 101.2 | NA | NA | NA | ||||||||||||||
| 6wy0 | 1 | P05164 | 100.0 | 5e-70 |
X-RAY |
2020-10-14 | GLU | A:36 | A:36 | 116.0 | 0.611 | -122.8 | 104.5 | 65.0 | 0.342 | 0.269 |
B:P05164:0.268 |
CL HOH |
9.076 3.021 |
N O |
CL O |
||
| GLU | C:36 | D:36 | 126.0 | 0.663 | -120.4 | 102.6 | NA | NA | NA | ||||||||||||||
| GLU | E:36 | F:36 | 127.0 | 0.668 | -121.8 | 104.4 | NA | NA | NA | ||||||||||||||
| GLU | G:36 | H:36 | 122.0 | 0.642 | -120.9 | 104.1 | NA | NA | NA | ||||||||||||||
| 6wy5 | 1 | P05164 | 100.0 | 5e-70 |
X-RAY |
2020-10-14 | GLU | A:36 | A:36 | 124.0 | 0.653 | -117.0 | 103.8 | 73.0 | 0.384 | 0.269 |
B:P05164:0.268 |
CL |
9.207 |
N |
CL |
||
| GLU | C:36 | D:36 | 127.0 | 0.668 | -117.1 | 103.3 | NA | NA | NA | ||||||||||||||
| 6wy7 | 1 | P05164 | 100.0 | 5e-70 |
X-RAY |
2020-10-14 | GLU | A:36 | A:36 | 123.0 | 0.647 | -124.1 | 105.0 | 69.0 | 0.363 | 0.284 |
B:P05164:0.284 |
CL HOH |
9.165 2.639 |
N OE1 |
CL O |
||
| GLU | C:36 | D:36 | 123.0 | 0.647 | -123.4 | 104.9 | NA | NA | NA | ||||||||||||||
| 6wyd | 1 | P05164 | 100.0 | 5e-70 |
X-RAY |
2020-10-14 | GLU | A:36 | A:36 | 120.0 | 0.632 | -118.1 | 100.3 | 64.0 | 0.337 | 0.295 |
B:P05164:0.295 |
CL NAG HOH |
9.099 9.177 2.834 |
N OE2 O |
CL C8 O |
||
| GLU | C:36 | D:36 | 120.0 | 0.632 | -120.0 | 112.6 | NA | NA | NA | ||||||||||||||
| GLU | E:36 | F:36 | 124.0 | 0.653 | -128.0 | 105.1 | NA | NA | NA | ||||||||||||||
| GLU | G:36 | H:36 | 131.0 | 0.689 | -103.3 | 103.4 | NA | NA | NA | ||||||||||||||
| 7lae | 1 | P05164 | 100.0 | 5e-70 |
X-RAY |
2021-04-21 | GLU | A:36 | A:36 | 126.0 | 0.663 | -105.1 | 99.5 | 74.0 | 0.389 | 0.274 |
B:P05164:0.274 |
NAG CL |
8.875 9.481 |
OE2 N |
C8 CL |
||
| GLU | C:36 | D:36 | 129.0 | 0.679 | -104.0 | 99.0 | NA | NA | NA | ||||||||||||||
| 7lag | 1 | P05164 | 100.0 | 5e-70 |
X-RAY |
2021-04-21 | GLU | A:36 | A:36 | 118.0 | 0.621 | -126.3 | 100.4 | 62.0 | 0.326 | 0.295 |
B:P05164:0.295 |
CL NAG |
9.164 9.473 |
N OE2 |
CL C8 |
||
| GLU | C:36 | D:36 | 119.0 | 0.626 | -127.3 | 100.4 | NA | NA | NA | ||||||||||||||
| GLU | E:36 | F:36 | 120.0 | 0.632 | -125.8 | 100.9 | NA | NA | NA | ||||||||||||||
| GLU | G:36 | H:36 | 120.0 | 0.632 | -127.3 | 100.5 | NA | NA | NA | ||||||||||||||
| 7lal | 1 | P05164 | 100.0 | 5e-70 |
X-RAY |
2021-04-21 | GLU | A:36 | A:36 | 113.0 | 0.595 | -119.2 | 109.5 | 64.0 | 0.337 | 0.258 |
B:P05164:0.258 |
NAG CL |
9.576 9.331 |
OE2 N |
C8 CL |
||
| GLU | C:36 | D:36 | 115.0 | 0.605 | -118.9 | 108.2 | NA | NA | NA | ||||||||||||||
| 7lan | 1 | P05164 | 100.0 | 5e-70 |
X-RAY |
2021-04-21 | GLU | A:36 | A:36 | 125.0 | 0.658 | -128.6 | 105.9 | 70.0 | 0.368 | 0.29 |
B:P05164:0.289 |
CL HOH |
9.128 2.594 |
N OE1 |
CL O |
||
| GLU | C:36 | D:36 | 126.0 | 0.663 | -127.7 | 104.2 | NA | NA | NA | ||||||||||||||
| GLU | E:36 | F:36 | 127.0 | 0.668 | -128.4 | 103.4 | NA | NA | NA | ||||||||||||||
| GLU | G:36 | H:36 | 126.0 | 0.663 | -129.2 | 105.7 | NA | NA | NA | ||||||||||||||
| 1cxp | 1 | P05164 | 100.0 | 2e-69 |
X-RAY |
2000-04-24 | GLU | A:36 | A:36 | 128.0 | 0.674 | -124.6 | 100.0 | 8.0 | 0.042 | 0.632 |
B:P05164:0.3 C:P05164:0.395 |
NAG CL HOH |
9.383 9.017 2.706 |
OE2 N OE1 |
C8 CL O |
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| GLU | C:36 | B:36 | 125.0 | 0.658 | -125.6 | 98.8 | 8.0 | 0.042 | 0.616 |
D:P05164:0.295 A:P05164:0.384 |
NAG CL HOH |
9.295 8.990 2.723 |
OE2 N OE1 |
C8 CL O |
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| 1d2v | 1 | P05164 | 100.0 | 2e-69 |
X-RAY |
2000-04-24 | GLU | A:36 | A:36 | 127.0 | 0.668 | -119.9 | 97.8 | 8.0 | 0.042 | 0.626 |
B:P05164:0.295 C:P05164:0.389 |
NAG BR HOH |
9.476 8.833 2.620 |
OE2 N OE1 |
C8 BR O |
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| GLU | C:36 | B:36 | 127.0 | 0.668 | -123.6 | 98.4 | 7.0 | 0.037 | 0.631 |
D:P05164:0.295 A:P05164:0.4 |
NAG BR HOH |
9.463 8.840 2.580 |
OE2 N OE1 |
C8 BR O |
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| 1d5l | 1 | P05164 | 100.0 | 2e-69 |
X-RAY |
2001-12-12 | GLU | A:36 | A:36 | 128.0 | 0.674 | -124.6 | 99.2 | 8.0 | 0.042 | 0.632 |
B:P05164:0.289 C:P05164:0.4 |
NAG CL HOH |
9.380 9.046 2.734 |
OE2 N OE1 |
C8 CL O |
||
| GLU | C:36 | B:36 | 124.0 | 0.653 | -123.5 | 100.9 | 9.0 | 0.047 | 0.606 |
D:P05164:0.274 A:P05164:0.389 |
NAG CL HOH |
9.338 8.998 2.657 |
OE2 N OE2 |
C8 CL O |
|||||||||
| 1d7w | 1 | P05164 | 100.0 | 2e-69 |
X-RAY |
2001-12-12 | GLU | A:36 | A:36 | 130.0 | 0.684 | -122.3 | 98.2 | 7.0 | 0.037 | 0.647 |
B:P05164:0.295 C:P05164:0.416 |
NAG BR ACT ACT HOH |
9.356 8.817 4.364 9.458 2.751 |
OE2 N OE2 OE1 OE1 |
C8 BR O OXT O |
||
| GLU | C:36 | B:36 | 125.0 | 0.658 | -123.7 | 93.5 | 8.0 | 0.042 | 0.616 |
A:P05164:0.384 D:P05164:0.295 |
NAG ACT BR HOH |
9.231 4.859 8.763 2.543 |
OE2 OE2 N OE1 |
C8 O BR O |
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| 1dnu | 1 | P05164 | 100.0 | 2e-69 |
X-RAY |
2001-12-21 | GLU | A:36 | A:36 | 126.0 | 0.663 | -124.8 | 99.0 | 8.0 | 0.042 | 0.621 |
B:P05164:0.295 C:P05164:0.384 |
NAG SCN HOH |
9.481 6.761 2.677 |
OE2 N OE1 |
C8 S O |
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| GLU | C:36 | B:36 | 124.0 | 0.653 | -125.2 | 103.8 | 7.0 | 0.037 | 0.616 |
D:P05164:0.295 A:P05164:0.384 |
NAG SCN HOH |
9.257 6.615 2.607 |
OE2 N OE1 |
C8 S O |
|||||||||
| 1dnw | 1 | P05164 | 100.0 | 2e-69 |
X-RAY |
2001-12-21 | GLU | A:36 | A:36 | 125.0 | 0.658 | -128.1 | 99.2 | 8.0 | 0.042 | 0.616 |
B:P05164:0.279 C:P05164:0.395 |
NAG SCN HOH |
9.385 6.725 2.626 |
OE2 N OE1 |
C8 S O |
||
| GLU | C:36 | B:36 | 121.0 | 0.637 | -123.0 | 101.9 | 8.0 | 0.042 | 0.595 |
A:P05164:0.374 D:P05164:0.279 |
NAG SCN HOH |
9.315 6.655 2.680 |
OE2 N OE2 |
C8 S O |
|||||||||
| 4dl1 | 1 | P05164 | 100.0 | 2e-69 |
X-RAY |
2012-03-21 | GLU | A:36 | A:36 | 129.0 | 0.679 | -123.4 | 104.4 | 12.0 | 0.063 | 0.616 |
B:P05164:0.284 C:P05164:0.389 |
NAG CL HOH |
9.187 9.067 2.683 |
OE2 N OE1 |
C8 CL O |
||
| GLU | C:36 | B:36 | 128.0 | 0.674 | -125.9 | 102.7 | 12.0 | 0.063 | 0.611 |
D:P05164:0.284 A:P05164:0.379 |
NAG CL HOH |
9.332 8.971 2.563 |
OE2 N OE1 |
C8 CL O |
|||||||||
| GLU | E:36 | E:36 | 127.0 | 0.668 | -126.0 | 104.3 | NA | NA | NA | ||||||||||||||
| GLU | G:36 | F:36 | 123.0 | 0.647 | -123.2 | 106.1 | NA | NA | NA | ||||||||||||||
| GLU | I:36 | I:36 | 131.0 | 0.689 | -128.4 | 104.0 | NA | NA | NA | ||||||||||||||
| GLU | K:36 | J:36 | 122.0 | 0.642 | -125.3 | 108.7 | NA | NA | NA | ||||||||||||||
| GLU | M:36 | M:36 | 128.0 | 0.674 | -124.7 | 106.8 | NA | NA | NA | ||||||||||||||
| GLU | O:36 | N:36 | 130.0 | 0.684 | -129.9 | 111.1 | NA | NA | NA | ||||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05164-f1 | 1 | P05164 | 100.0 | 0.0 | GLU | A:202 | A:202 | 69.0 | 0.363 | -113.3 | 87.4 | ||