Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 56356735 . C A CCDS11604.1:NM_000250.1:c.601Gcg>Tcg_NP_000241.1:p.201A>S Homo sapiens myeloperoxidase (MPO), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bmt 1 P05164 100.0 0.0 X-RAY
 2018-01-03 ALA A:201 A:201 20.0 0.174 -57.2 145.6 20.0 0.174 0.0 CL
HOH
 7.189
4.270
 N
N
 CL
O
5mfa 1 P05164 100.0 0.0 X-RAY
 2017-04-05 ALA A:153 A:201 21.0 0.183 -64.2 148.6 21.0 0.183 0.0 CL
HOH
 6.731
2.211
 HA
H
 CL
O
5uzu 2 P05164 100.0 0.0 X-RAY
 2017-07-26 ALA B:35 A:201 19.0 0.165 -65.1 149.1 19.0 0.165 0.0 CL
HOH
 6.998
3.200
 N
O
 CL
O
6azp 1 P05164 100.0 0.0 X-RAY
 2017-12-27 ALA A:35 A:201 23.0 0.2 -61.4 157.8 23.0 0.2 0.0 HOH
 2.609
 N
 O
3f9p 1 P05164 100.0 1e-76 X-RAY
 2009-07-14 ALA A:37 A:35 40.0 0.348 -70.3 144.0 16.0 0.139 0.209 B:P05164:0.209
 CL
 7.349
 N
 CL
ALA C:37 B:35 41.0 0.357 -67.9 144.6 NA NA NA
3zs1 1 P05164 100.0 1e-76 X-RAY
 2011-08-31 ALA A:37 A:35 40.0 0.348 -57.7 150.3 NA NA NA
ALA B:37 B:35 37.0 0.322 -68.4 138.5 17.0 0.148 0.174 D:P05164:0.174
 CL
HOH
 7.193
4.137
 N
N
 CL
O
4ejx 2 P05164 100.0 1e-76 X-RAY
 2013-04-10 ALA B:37 B:35 37.0 0.322 -68.3 138.5 17.0 0.148 0.174 C:P05164:0.174
1mhl 1 P05164 100.0 3e-72 X-RAY
 1996-01-06 ALA A:37 A:35 39.0 0.339 -72.9 153.1 2.0 0.017 0.322 B:P05164:0.191
C:P05164:0.148
 CL
HOH
 7.182
2.968
 N
N
 CL
O
ALA C:37 B:35 37.0 0.322 -68.4 154.6 1.0 0.009 0.313 D:P05164:0.191
A:P05164:0.139
 CL
HOH
 7.274
2.941
 N
N
 CL
O
1myp 1 P05164 100.0 3e-72 X-RAY
 1994-01-31 ALA A:37 A:35 35.0 0.304 -100.2 142.2 5.0 0.043 0.261 B:P05164:0.148
C:P05164:0.122
ALA C:37 B:35 40.0 0.348 -56.3 152.0 6.0 0.052 0.296 D:P05164:0.165
A:P05164:0.139
3zs0 1 P05164 100.0 3e-72 X-RAY
 2011-08-31 ALA A:37 A:35 39.0 0.339 -60.5 149.6 2.0 0.017 0.322 B:P05164:0.139
C:P05164:0.191
 CL
HOH
 7.172
2.814
 N
O
 CL
O
ALA B:37 B:35 39.0 0.339 -73.0 150.0 3.0 0.026 0.313 A:P05164:0.139
D:P05164:0.174
 CL
HOH
 7.241
2.551
 N
O
 CL
O
4c1m 1 P05164 100.0 3e-72 X-RAY
 2013-11-13 ALA A:37 A:35 40.0 0.348 -67.9 149.0 NA NA NA
ALA B:37 B:35 37.0 0.322 -60.3 150.4 17.0 0.148 0.174 D:P05164:0.174
 CL
HOH
 7.123
3.226
 N
N
 CL
O
5fiw 1 P05164 100.0 5e-70 X-RAY
 2015-10-14 ALA A:35 A:35 41.0 0.357 -62.5 153.8 17.0 0.148 0.209 C:P05164:0.209
 CL
HOH
 7.188
2.726
 N
O
 CL
O
ALA B:35 B:35 38.0 0.33 -68.9 152.4 NA NA NA
5qj2 1 P05164 100.0 5e-70 X-RAY
 2019-02-06 ALA A:35 A:35 32.0 0.278 -66.2 153.6 14.0 0.122 0.156 B:P05164:0.157
 HOH
 9.923
 CB
 O
ALA C:35 D:35 40.0 0.348 -69.4 136.5 NA NA NA
ALA E:35 F:35 40.0 0.348 -57.9 145.4 NA NA NA
ALA G:35 H:35 41.0 0.357 -53.9 165.7 NA NA NA
5qj3 1 P05164 100.0 5e-70 X-RAY
 2019-02-06 ALA A:35 A:35 38.0 0.33 -61.7 149.3 18.0 0.157 0.173 B:P05164:0.174
 CL
HOH
 7.302
2.806
 N
O
 CL
O
ALA C:35 D:35 38.0 0.33 -59.6 148.9 NA NA NA
5wdj 1 P05164 100.0 5e-70 X-RAY
 2018-04-18 ALA A:35 A:35 36.0 0.313 -69.0 151.9 1.0 0.009 0.304 B:P05164:0.2
C:P05164:0.122
 CL
HOH
 7.526
2.841
 N
O
 CL
O
ALA C:35 D:35 36.0 0.313 -72.5 156.1 1.0 0.009 0.304 D:P05164:0.2
A:P05164:0.122
 CL
HOH
 7.360
2.956
 N
N
 CL
O
6wxz 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 ALA A:35 A:35 38.0 0.33 -69.1 153.5 14.0 0.122 0.208 B:P05164:0.209
 CL
HOH
 7.262
2.652
 N
O
 CL
O
ALA C:35 D:35 38.0 0.33 -69.1 153.2 NA NA NA
6wy0 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 ALA A:35 A:35 38.0 0.33 -66.1 152.8 16.0 0.139 0.191 B:P05164:0.191
 CL
HOH
 7.264
7.092
 N
C
 CL
O
ALA C:35 D:35 39.0 0.339 -66.4 150.9 NA NA NA
ALA E:35 F:35 38.0 0.33 -67.1 151.8 NA NA NA
ALA G:35 H:35 37.0 0.322 -65.1 151.9 NA NA NA
6wy5 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 ALA A:35 A:35 39.0 0.339 -68.8 147.5 14.0 0.122 0.217 B:P05164:0.217
 CL
 7.264
 N
 CL
ALA C:35 D:35 38.0 0.33 -67.4 147.1 NA NA NA
6wy7 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 ALA A:35 A:35 38.0 0.33 -66.1 153.9 15.0 0.13 0.2 B:P05164:0.2
 CL
HOH
 7.308
2.699
 N
O
 CL
O
ALA C:35 D:35 38.0 0.33 -67.9 154.0 NA NA NA
6wyd 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 ALA A:35 A:35 36.0 0.313 -56.5 145.2 14.0 0.122 0.191 B:P05164:0.191
 CL
HOH
 7.270
3.176
 N
N
 CL
O
ALA C:35 D:35 36.0 0.313 -68.2 150.5 NA NA NA
ALA E:35 F:35 36.0 0.313 -61.5 156.2 NA NA NA
ALA G:35 H:35 37.0 0.322 -68.3 135.8 NA NA NA
7lae 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 ALA A:35 A:35 36.0 0.313 -68.5 137.4 15.0 0.13 0.183 B:P05164:0.183
 CL
 7.681
 N
 CL
ALA C:35 D:35 36.0 0.313 -69.2 136.0 NA NA NA
7lag 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 ALA A:35 A:35 38.0 0.33 -60.5 153.7 15.0 0.13 0.2 B:P05164:0.2
 CL
 7.311
 N
 CL
ALA C:35 D:35 39.0 0.339 -61.3 153.7 NA NA NA
ALA E:35 F:35 40.0 0.348 -60.6 153.1 NA NA NA
ALA G:35 H:35 38.0 0.33 -58.9 154.7 NA NA NA
7lal 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 ALA A:35 A:35 38.0 0.33 -70.9 149.8 15.0 0.13 0.2 B:P05164:0.2
 CL
 7.430
 N
 CL
ALA C:35 D:35 39.0 0.339 -69.3 148.6 NA NA NA
7lan 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 ALA A:35 A:35 37.0 0.322 -68.7 157.1 14.0 0.122 0.2 B:P05164:0.2
 CL
HOH
 7.265
2.765
 N
N
 CL
O
ALA C:35 D:35 40.0 0.348 -66.4 154.0 NA NA NA
ALA E:35 F:35 39.0 0.339 -66.1 155.1 NA NA NA
ALA G:35 H:35 39.0 0.339 -69.0 157.4 NA NA NA
1cxp 1 P05164 100.0 2e-69 X-RAY
 2000-04-24 ALA A:35 A:35 39.0 0.339 -64.0 152.6 3.0 0.026 0.313 B:P05164:0.191
C:P05164:0.148
 CL
HOH
 7.177
2.820
 N
O
 CL
O
ALA C:35 B:35 37.0 0.322 -67.3 152.9 1.0 0.009 0.313 D:P05164:0.183
A:P05164:0.139
 CL
HOH
 7.158
2.715
 N
O
 CL
O
1d2v 1 P05164 100.0 2e-69 X-RAY
 2000-04-24 ALA A:35 A:35 42.0 0.365 -65.0 147.6 2.0 0.017 0.348 B:P05164:0.2
C:P05164:0.165
 BR
HOH
 7.045
2.558
 N
O
 BR
O
ALA C:35 B:35 38.0 0.33 -71.4 154.0 1.0 0.009 0.321 D:P05164:0.191
A:P05164:0.139
 BR
HOH
 7.074
2.611
 N
O
 BR
O
1d5l 1 P05164 100.0 2e-69 X-RAY
 2001-12-12 ALA A:35 A:35 39.0 0.339 -67.6 151.0 2.0 0.017 0.322 B:P05164:0.191
C:P05164:0.148
 CL
HOH
 7.252
2.804
 N
O
 CL
O
ALA C:35 B:35 38.0 0.33 -72.3 151.4 1.0 0.009 0.321 D:P05164:0.209
A:P05164:0.139
 CL
HOH
 7.251
2.704
 N
O
 CL
O
1d7w 1 P05164 100.0 2e-69 X-RAY
 2001-12-12 ALA A:35 A:35 39.0 0.339 -66.8 150.4 2.0 0.017 0.322 B:P05164:0.191
C:P05164:0.148
 BR
ACT
HOH
 7.023
5.860
2.817
 N
O
O
 BR
O
O
ALA C:35 B:35 40.0 0.348 -63.8 152.3 2.0 0.017 0.331 A:P05164:0.157
D:P05164:0.191
 ACT
BR
HOH
 5.862
7.018
2.663
 O
N
O
 O
BR
O
1dnu 1 P05164 100.0 2e-69 X-RAY
 2001-12-21 ALA A:35 A:35 41.0 0.357 -66.1 151.7 2.0 0.017 0.34 B:P05164:0.209
C:P05164:0.165
 SCN
HOH
 5.267
2.784
 N
O
 S
O
ALA C:35 B:35 39.0 0.339 -68.1 152.8 3.0 0.026 0.313 D:P05164:0.191
A:P05164:0.139
 SCN
HOH
 5.215
2.769
 N
O
 S
O
1dnw 1 P05164 100.0 2e-69 X-RAY
 2001-12-21 ALA A:35 A:35 40.0 0.348 -67.2 153.7 2.0 0.017 0.331 B:P05164:0.209
C:P05164:0.157
 SCN
HOH
 5.202
2.890
 N
O
 S
O
ALA C:35 B:35 38.0 0.33 -62.4 146.6 2.0 0.017 0.313 A:P05164:0.139
D:P05164:0.191
 SCN
HOH
 5.135
2.881
 N
O
 S
O
4dl1 1 P05164 100.0 2e-69 X-RAY
 2012-03-21 ALA A:35 A:35 40.0 0.348 -72.5 147.2 2.0 0.017 0.331 B:P05164:0.2
C:P05164:0.157
 CL
HOH
 7.263
2.699
 N
O
 CL
O
ALA C:35 B:35 40.0 0.348 -67.2 151.0 1.0 0.009 0.339 D:P05164:0.2
A:P05164:0.157
 CL
HOH
 7.167
2.761
 N
O
 CL
O
ALA E:35 E:35 38.0 0.33 -71.4 153.7 NA NA NA
ALA G:35 F:35 38.0 0.33 -68.2 148.3 NA NA NA
ALA I:35 I:35 38.0 0.33 -68.4 156.0 NA NA NA
ALA K:35 J:35 39.0 0.339 -57.2 147.4 NA NA NA
ALA M:35 M:35 39.0 0.339 -70.1 153.7 NA NA NA
ALA O:35 N:35 38.0 0.33 -67.8 155.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05164-f1 1 P05164 100.0 0.0 ALA A:201 A:201 22.0 0.191 -71.1 144.5