Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 56356914 . T A CCDS11604.1:NM_000250.1:c.518tAc>tTc_NP_000241.1:p.173Y>F Homo sapiens myeloperoxidase (MPO), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bmt 1 P05164 100.0 0.0 X-RAY
 2018-01-03 TYR A:173 A:173 44.0 0.191 S -128.5 155.3 44.0 0.191 0.0 HOH
 2.656
 N
 O
5mfa 1 P05164 100.0 0.0 X-RAY
 2017-04-05 TYR A:125 A:173 30.0 0.13 S -136.5 159.7 30.0 0.13 0.0 HOH
 2.258
 H
 O
5uzu 2 P05164 100.0 0.0 X-RAY
 2017-07-26 TYR B:7 A:173 45.0 0.196 S -112.0 152.1 45.0 0.196 0.0 HOH
 2.436
 O
 O
6azp 1 P05164 100.0 0.0 X-RAY
 2017-12-27 TYR A:7 A:173 49.0 0.213 S -116.1 153.6 49.0 0.213 0.0 HOH
 3.110
 O
 O
3f9p 1 P05164 100.0 1e-76 X-RAY
 2009-07-14 TYR A:9 A:7 184.0 0.8 S -129.0 170.0 40.0 0.174 0.626 B:P05164:0.626
TYR C:9 B:7 188.0 0.817 S -125.8 167.5 NA NA NA
3zs1 1 P05164 100.0 1e-76 X-RAY
 2011-08-31 TYR A:9 A:7 174.0 0.757 S -134.4 155.3 NA NA NA
TYR B:9 B:7 179.0 0.778 S -116.8 154.2 27.0 0.117 0.661 D:P05164:0.661
 HOH
 3.789
 CE1
 O
4ejx 2 P05164 100.0 1e-76 X-RAY
 2013-04-10 TYR B:9 B:7 179.0 0.778 S -116.8 154.2 32.0 0.139 0.639 C:P05164:0.639
1mhl 1 P05164 100.0 3e-72 X-RAY
 1996-01-06 TYR A:9 A:7 188.0 0.817 S -127.9 160.3 47.0 0.204 0.613 B:P05164:0.613
 HOH
 2.953
 O
 O
TYR C:9 B:7 185.0 0.804 S -126.3 159.5 49.0 0.213 0.591 D:P05164:0.591
 HOH
 2.790
 O
 O
1myp 1 P05164 100.0 3e-72 X-RAY
 1994-01-31 TYR A:9 A:7 181.0 0.787 S -137.5 167.5 43.0 0.187 0.6 B:P05164:0.6
TYR C:9 B:7 186.0 0.809 S -106.2 155.3 37.0 0.161 0.648 D:P05164:0.648
3zs0 1 P05164 100.0 3e-72 X-RAY
 2011-08-31 TYR A:9 A:7 178.0 0.774 S -130.4 152.2 45.0 0.196 0.578 C:P05164:0.578
 HOH
 2.920
 O
 O
TYR B:9 B:7 180.0 0.783 S -121.8 156.7 28.0 0.122 0.661 D:P05164:0.661
 HOH
 3.345
 N
 O
4c1m 1 P05164 100.0 3e-72 X-RAY
 2013-11-13 TYR A:9 A:7 176.0 0.765 S -123.2 150.4 NA NA NA
TYR B:9 B:7 179.0 0.778 S -119.6 154.8 33.0 0.143 0.635 D:P05164:0.635
 HOH
 2.962
 O
 O
5fiw 1 P05164 100.0 5e-70 X-RAY
 2015-10-14 TYR A:7 A:7 177.0 0.77 S -125.8 156.6 44.0 0.191 0.579 C:P05164:0.578
 HOH
 2.909
 O
 O
TYR B:7 B:7 180.0 0.783 S -126.3 150.8 NA NA NA
5qj2 1 P05164 100.0 5e-70 X-RAY
 2019-02-06 TYR A:7 A:7 206.0 0.896 S -124.4 -179.6 49.0 0.213 0.683 B:P05164:0.683
TYR C:7 D:7 200.0 0.87 S -117.2 160.4 NA NA NA
TYR E:7 F:7 205.0 0.891 S -134.9 164.9 NA NA NA
TYR G:7 H:7 202.0 0.878 S -127.8 162.9 NA NA NA
5qj3 1 P05164 100.0 5e-70 X-RAY
 2019-02-06 TYR A:7 A:7 201.0 0.874 S -127.4 166.2 51.0 0.222 0.652 B:P05164:0.652
 HOH
 2.701
 O
 O
TYR C:7 D:7 200.0 0.87 S -125.3 163.2 NA NA NA
5wdj 1 P05164 100.0 5e-70 X-RAY
 2018-04-18 TYR A:7 A:7 202.0 0.878 S -129.2 160.6 51.0 0.222 0.656 B:P05164:0.657
 HOH
 2.993
 N
 O
TYR C:7 D:7 199.0 0.865 S -132.9 165.0 51.0 0.222 0.643 D:P05164:0.643
 HOH
 2.636
 O
 O
6wxz 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 TYR A:7 A:7 202.0 0.878 S -124.9 161.3 52.0 0.226 0.652 B:P05164:0.652
 HOH
 3.491
 CA
 O
TYR C:7 D:7 204.0 0.887 S -123.7 162.2 NA NA NA
6wy0 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 TYR A:7 A:7 205.0 0.891 S -125.9 164.0 52.0 0.226 0.665 B:P05164:0.665
TYR C:7 D:7 196.0 0.852 S -125.7 164.8 NA NA NA
TYR E:7 F:7 200.0 0.87 S -125.8 164.1 NA NA NA
TYR G:7 H:7 203.0 0.883 S -126.8 166.3 NA NA NA
6wy5 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 TYR A:7 A:7 204.0 0.887 S -127.5 159.1 56.0 0.243 0.644 B:P05164:0.643
TYR C:7 D:7 201.0 0.874 S -126.6 157.2 NA NA NA
6wy7 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 TYR A:7 A:7 181.0 0.787 S -124.3 159.9 47.0 0.204 0.583 B:P05164:0.583
 HOH
 2.879
 O
 O
TYR C:7 D:7 178.0 0.774 S -124.7 161.3 NA NA NA
6wyd 1 P05164 100.0 5e-70 X-RAY
 2020-10-14 TYR A:7 A:7 197.0 0.857 S -129.6 158.1 48.0 0.209 0.648 B:P05164:0.648
 HOH
 2.670
 O
 O
TYR C:7 D:7 208.0 0.904 S -122.6 155.5 NA NA NA
TYR E:7 F:7 204.0 0.887 S -120.3 167.4 NA NA NA
TYR G:7 H:7 205.0 0.891 S -116.3 156.7 NA NA NA
7lae 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 TYR A:7 A:7 203.0 0.883 S -128.1 158.6 52.0 0.226 0.657 B:P05164:0.657
TYR C:7 D:7 204.0 0.887 S -128.5 160.2 NA NA NA
7lag 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 TYR A:7 A:7 202.0 0.878 S -123.0 157.7 54.0 0.235 0.643 B:P05164:0.643
TYR C:7 D:7 202.0 0.878 S -123.1 157.6 NA NA NA
TYR E:7 F:7 201.0 0.874 S -121.5 155.4 NA NA NA
TYR G:7 H:7 200.0 0.87 S -123.6 161.6 NA NA NA
7lal 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 TYR A:7 A:7 203.0 0.883 S -119.6 161.0 60.0 0.261 0.622 B:P05164:0.622
TYR C:7 D:7 202.0 0.878 S -120.4 163.2 NA NA NA
7lan 1 P05164 100.0 5e-70 X-RAY
 2021-04-21 TYR A:7 A:7 202.0 0.878 S -126.5 155.0 53.0 0.23 0.648 B:P05164:0.648
 HOH
 5.054
 O
 O
TYR C:7 D:7 188.0 0.817 S -125.1 156.0 NA NA NA
TYR E:7 F:7 201.0 0.874 S -125.1 155.1 NA NA NA
TYR G:7 H:7 203.0 0.883 S -123.9 157.6 NA NA NA
1cxp 1 P05164 100.0 2e-69 X-RAY
 2000-04-24 TYR A:7 A:7 175.0 0.761 S -135.4 155.4 41.0 0.178 0.583 B:P05164:0.583
 HOH
 2.933
 O
 O
TYR C:7 B:7 185.0 0.804 S -140.6 167.7 29.0 0.126 0.678 D:P05164:0.678
 HOH
 2.698
 O
 O
1d2v 1 P05164 100.0 2e-69 X-RAY
 2000-04-24 TYR A:7 A:7 172.0 0.748 S -126.9 152.9 42.0 0.183 0.565 B:P05164:0.565
 HOH
 2.953
 O
 O
TYR C:7 B:7 181.0 0.787 S -145.9 173.5 28.0 0.122 0.665 D:P05164:0.665
 HOH
 2.619
 O
 O
1d5l 1 P05164 100.0 2e-69 X-RAY
 2001-12-12 TYR A:7 A:7 176.0 0.765 S -130.6 155.3 45.0 0.196 0.569 B:P05164:0.57
 HOH
 2.744
 O
 O
TYR C:7 B:7 185.0 0.804 S -138.6 170.6 26.0 0.113 0.691 D:P05164:0.691
 HOH
 2.703
 O
 O
1d7w 1 P05164 100.0 2e-69 X-RAY
 2001-12-12 TYR A:7 A:7 170.0 0.739 S -130.3 152.2 40.0 0.174 0.565 B:P05164:0.565
 HOH
 2.508
 CE2
 O
TYR C:7 B:7 183.0 0.796 S -139.4 168.5 23.0 0.1 0.696 D:P05164:0.696
 HOH
 2.695
 CE2
 O
1dnu 1 P05164 100.0 2e-69 X-RAY
 2001-12-21 TYR A:7 A:7 175.0 0.761 S -128.5 158.9 42.0 0.183 0.578 B:P05164:0.578
 HOH
 2.887
 O
 O
TYR C:7 B:7 191.0 0.83 S -141.0 173.1 32.0 0.139 0.691 D:P05164:0.691
 HOH
 2.706
 O
 O
1dnw 1 P05164 100.0 2e-69 X-RAY
 2001-12-21 TYR A:7 A:7 177.0 0.77 S -132.7 156.5 44.0 0.191 0.579 B:P05164:0.578
 HOH
 2.750
 O
 O
TYR C:7 B:7 186.0 0.809 S -134.3 174.9 28.0 0.122 0.687 D:P05164:0.687
 HOH
 2.761
 N
 O
4dl1 1 P05164 100.0 2e-69 X-RAY
 2012-03-21 TYR A:7 A:7 171.0 0.743 S -126.7 145.2 45.0 0.196 0.547 B:P05164:0.548
 HOH
 2.804
 O
 O
TYR C:7 B:7 176.0 0.765 S -122.6 152.1 50.0 0.217 0.548 D:P05164:0.548
 HOH
 2.902
 O
 O
TYR E:7 E:7 180.0 0.783 S -133.0 162.4 NA NA NA
TYR G:7 F:7 181.0 0.787 S -117.4 149.7 NA NA NA
TYR I:7 I:7 185.0 0.804 S -129.1 151.6 NA NA NA
TYR K:7 J:7 170.0 0.739 S -126.1 151.1 NA NA NA
TYR M:7 M:7 190.0 0.826 S -130.4 147.0 NA NA NA
TYR O:7 N:7 182.0 0.791 S -129.1 147.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05164-f1 1 P05164 100.0 0.0 TYR A:173 A:173 48.0 0.209 S -122.9 143.2