Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 78111999 . T A CCDS11767.1:NM_014740.3:c.809gAc>gTc_NP_055555.1:p.270D>V Homo sapiens eukaryotic translation initiation factor 4A3 (EIF4A3), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2hyi 4 P38919 100.0 0.0 X-RAY
 2006-08-15 ASP E:270 C:270 79.0 0.527 H -63.2 -33.1 79.0 0.527 0.0 HOH
 7.552
 O
 O
ASP I:270 I:270 133.0 0.887 H -65.6 -31.6 NA NA NA
3ex7 3 P38919 100.0 0.0 X-RAY
 2008-12-09 ASP C:270 C:270 137.0 0.913 H -65.9 -30.8 137.0 0.913 0.0 HOH
 2.724
 O
 O
ASP G:270 H:270 129.0 0.86 H -64.9 -59.4 NA NA NA
2xb2 1 P38919 100.0 0.0 X-RAY
 2010-05-12 ASP A:270 A:270 125.0 0.833 H -59.5 -42.9 NA NA NA
ASP K:270 X:270 125.0 0.833 H -59.9 -43.6 94.0 0.627 0.206 J:Q9BZI7:0.207
4c9b 1 P38919 100.0 0.0 X-RAY
 2013-11-13 ASP A:270 A:270 90.0 0.6 H -71.1 -39.1 14.0 0.093 0.507 B:Q9HCG8:0.507
 GOL
HOH
 4.689
3.052
 N
OD2
 H2
O
5mqf 30 P38919 100.0 0.0 EM
 2017-03-22 ASP NA:270 p:270 NA NA NA NA NA NA NA NA
5xjc 37 P38919 100.0 0.0 EM
 2017-07-05 ASP UA:270 u:270 75.0 0.5 H -63.2 -33.1 75.0 0.5 0.0
5yzg 29 P38919 100.0 0.0 EM
 2018-08-08 ASP FA:270 u:270 76.0 0.507 H -63.2 -33.1 76.0 0.507 0.0
6icz 3 P38919 100.0 0.0 EM
 2019-03-13 ASP C:270 u:270 82.0 NA H -63.1 -33.1 82.0 NA NA
7a5p 37 P38919 100.0 0.0 EM
 2020-10-14 ASP UA:270 y:270 53.0 NA H -65.9 -32.9 53.0 NA NA
2j0q 1 P38919 100.0 0.0 X-RAY
 2006-08-30 ASP A:269 A:270 128.0 0.853 H -52.1 -47.6 128.0 0.853 0.0
ASP B:269 B:270 126.0 0.84 H -52.8 -47.2 NA NA NA
2j0s 1 P38919 100.0 0.0 X-RAY
 2006-09-06 ASP A:269 A:270 129.0 0.86 H -65.0 -33.9 129.0 0.86 0.0 HOH
 3.973
 OD2
 O
6qdv 4 P38919 100.0 0.0 EM
 2019-02-20 ASP D:249 7:270 78.0 0.52 H -63.2 -33.0 78.0 0.52 0.0
2hxy 1 P38919 100.0 0.0 X-RAY
 2006-08-15 ASP A:248 A:270 138.0 0.92 H -40.4 -38.7 138.0 0.92 0.0
ASP B:248 B:270 111.0 0.74 H -40.4 -49.5 NA NA NA
ASP C:248 C:270 125.0 0.833 H -40.6 -45.2 NA NA NA
ASP D:248 D:270 118.0 0.787 H -40.4 -46.7 NA NA NA
2j0u 1 P38919 98.93 0.0 X-RAY
 2006-09-06 ASP A:233 A:270 118.0 0.787 H -52.4 -50.1 118.0 0.787 0.0
2j0u 2 P38919 98.4 0.0 X-RAY
 2006-09-06 ASP B:233 B:270 132.0 0.88 H -48.9 -39.7 NA NA NA
6yvh 3 P38919 100.0 1e-121 X-RAY
 2020-05-13 ASP F:25 H:270 94.0 0.627 H -58.6 -38.8 11.0 0.073 0.554 A:Q9HCG8:0.553
ASP G:25 J:270 92.0 0.613 H -57.7 -38.3 11.0 0.073 0.54 B:Q9HCG8:0.54
ASP H:25 K:270 101.0 0.673 H -58.2 -37.9 18.0 0.12 0.553 E:Q9HCG8:0.553
ASP I:25 L:270 90.0 0.6 H -58.4 -38.8 42.0 0.28 0.32 D:Q9HCG8:0.32

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p38919-f1 1 P38919 100.0 0.0 ASP A:270 A:270 128.0 0.853 H -62.6 -35.9