Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 8065060 . C A CCDS32561.1:NM_014232.2:c.148Gtg>Ttg_NP_055047.2:p.50V>L Homo sapiens vesicle associated membrane protein 2 (VAMP2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1sfc 1 P63045 98.96 4e-66 X-RAY
 1998-10-28 VAL A:50 A:50 75.0 0.484 H -58.8 -49.0 28.0 0.181 0.303 B:P32851:0.303
 SR
 9.284
 CG2
 SR
VAL E:50 E:50 75.0 0.484 H -52.7 -33.0 NA NA NA
VAL I:50 I:50 78.0 0.503 H -57.7 -40.8 NA NA NA
6ip1 1 P63045 98.94 3e-64 EM
 2019-04-24 VAL A:53 A:50 79.0 0.51 H -74.2 -26.5 23.0 0.148 0.362 B:P32851:0.174
H:A5D7S0:0.194
6mdm 4 P63045 98.88 2e-60 EM
 2018-09-19 VAL I:78 J:50 66.0 0.426 H -71.8 -35.4 43.0 0.277 0.149 H:P32851:0.148
6mdn 4 P63045 98.88 2e-60 EM
 2018-09-19 VAL I:78 J:50 76.0 0.49 H -72.9 -35.7 31.0 0.2 0.29 H:P32851:0.29
3hd7 1 P63045 100.0 1e-59 X-RAY
 2009-07-14 VAL A:25 A:50 78.0 0.503 H -80.6 -27.8 40.0 0.258 0.245 B:P32851:0.245
VAL E:25 E:50 79.0 0.51 H -72.8 -27.9 NA NA NA
3ipd 1 P63045 100.0 1e-59 X-RAY
 2009-09-01 VAL A:25 A:50 76.0 0.49 H -63.5 -37.7 42.0 0.271 0.219 B:P32851:0.219
VAL E:25 E:50 74.0 0.477 H -62.8 -38.0 NA NA NA
2n1t 1 P63045 100.0 2e-45 NMR
 2015-06-03 VAL A:26 A:50 83.0 0.535 H -64.9 -36.3 48.0 0.31 0.225 B:P32851:0.226
1kil 1 P63045 100.0 3e-42 X-RAY
 2002-03-13 VAL A:24 A:50 80.0 0.516 H -61.1 -33.4 0.0 0.0 0.516 B:P32851:0.316
E:P63041:0.277
 HOH
 7.530
 N
 O
1n7s 1 P63045 100.0 4e-39 X-RAY
 2002-12-27 VAL A:24 A:50 71.0 0.458 H -62.8 -40.0 27.0 0.174 0.284 B:P32851:0.284
 HOH
 3.601
 CB
 O
3j96 3 P63045 100.0 4e-39 EM
 2015-01-28 VAL K:24 K:50 74.0 0.477 H -62.6 -36.9 23.0 0.148 0.329 L:P32851:0.161
H:P54921:0.168
3j97 3 P63045 100.0 4e-39 EM
 2015-01-28 VAL K:24 K:50 78.0 0.503 H -53.8 -36.8 17.0 0.11 0.393 L:P32851:0.303
H:P54921:0.09
3j98 3 P63045 100.0 4e-39 EM
 2015-01-28 VAL K:24 K:50 75.0 0.484 H -69.6 -34.5 11.0 0.071 0.413 H:P54921:0.097
L:P32851:0.342
3j99 3 P63045 100.0 4e-39 EM
 2015-01-28 VAL K:24 K:50 75.0 0.484 H -69.7 -34.3 8.0 0.052 0.432 H:P54921:0.116
L:P32851:0.342
5ccg 1 P63045 100.0 4e-39 X-RAY
 2015-08-12 VAL A:24 A:50 76.0 0.49 H -63.1 -41.4 4.0 0.026 0.464 F:P21707:0.148
B:P32851:0.394
VAL G:24 G:50 70.0 0.452 H -61.5 -39.8 NA NA NA
5cch 1 P63045 100.0 4e-39 X-RAY
 2015-08-12 VAL A:24 A:50 72.0 0.465 H -67.8 -44.6 5.0 0.032 0.433 B:P32851:0.355
F:P21707:0.142
5cci 1 P63045 100.0 4e-39 X-RAY
 2015-08-12 VAL A:24 A:50 70.0 0.452 H -63.2 -44.9 2.0 0.013 0.439 F:P21707:0.174
B:P32851:0.316
5kj7 1 P63025 100.0 4e-39 X-RAY
 2016-10-19 VAL A:24 A:50 77.0 0.497 H -64.4 -42.0 15.0 0.097 0.4 B:P32851:0.4
VAL G:24 G:50 71.0 0.458 H -62.6 -40.3 NA NA NA
5kj8 1 P63025 100.0 4e-39 X-RAY
 2016-10-19 VAL A:24 A:50 73.0 0.471 H -67.5 -42.7 19.0 0.123 0.348 B:P32851:0.348
VAL G:24 G:50 57.0 0.368 H -66.9 -42.1 NA NA NA
6mti 3 P63045 100.0 4e-39 EM
 2019-04-24 VAL G:24 A:50 70.0 0.452 H -63.2 -44.9 22.0 0.142 0.31 H:P32851:0.31
VAL K:24 E:50 71.0 0.458 H -63.2 -44.9 22.0 0.142 0.316 L:P32851:0.316
VAL O:24 I:50 72.0 0.465 H -63.3 -44.8 22.0 0.142 0.323 P:P32851:0.323
VAL S:24 M:50 72.0 0.465 H -63.3 -44.8 23.0 0.148 0.317 T:P32851:0.316
VAL W:24 Q:50 70.0 0.452 H -63.2 -44.9 22.0 0.142 0.31 X:P32851:0.31
VAL AA:24 U:50 69.0 0.445 H -63.2 -45.0 22.0 0.142 0.303 BA:P32851:0.303
6wvw 1 P63045 100.0 4e-39 X-RAY
 2021-03-17 VAL A:24 A:50 72.0 0.465 H -65.1 -41.9 33.0 0.213 0.252 B:P32851:0.252
 HOH
 2.971
 HG12
 O
VAL E:24 E:50 73.0 0.471 H -65.8 -42.5 NA NA NA
1l4a 1 P47194 86.57 2e-37 X-RAY
 2002-07-31 VAL A:35 A:59 79.0 0.51 H -65.8 -42.0 1.0 0.006 0.504 B:O46345:0.316
E:Q95PA1:0.29
5w5c 1 P63045 100.0 1e-20 X-RAY
 2017-08-23 VAL A:24 A:50 74.0 0.477 H -66.6 -42.6 0.0 0.0 0.477 E:P63041:0.29
B:P32851:0.271
 GOL
HOH
 8.700
7.834
 N
N
 O1
O
5w5d 1 P63045 100.0 1e-20 X-RAY
 2017-08-23 VAL A:24 A:50 71.0 0.458 H -66.2 -39.6 0.0 0.0 0.458 B:P32851:0.258
E:P63041:0.265
 HOH
 7.357
 O
 O
3fie 2 P63027 100.0 4e-19 X-RAY
 2009-06-23 VAL C:29 C:50 41.0 0.265 H -50.9 -31.6 27.0 0.174 0.091 A:Q57236:0.09
 HOH
 3.771
 N
 O
VAL D:29 D:50 37.0 0.239 H -45.5 -47.3 NA NA NA
3rk2 1 P63027 97.14 2e-16 X-RAY
 2011-07-27 VAL A:27 A:50 82.0 0.529 H -60.6 -37.4 25.0 0.161 0.368 B:P32851:0.368
 HOH
 7.556
 CG2
 O
VAL E:27 E:50 74.0 0.477 H -55.0 -39.4 NA NA NA
3rk3 1 P63027 97.14 2e-16 X-RAY
 2011-07-27 VAL A:27 A:50 80.0 0.516 H -59.1 -49.2 2.0 0.013 0.503 B:P32851:0.29
E:O14810:0.258
3rl0 1 P63027 97.14 2e-16 X-RAY
 2011-07-27 VAL A:27 A:50 72.0 0.465 H -68.7 -44.0 13.0 0.084 0.381 B:P32851:0.2
GA:O14810:0.226
VAL E:27 E:50 72.0 0.465 H -68.5 -45.1 NA NA NA
VAL I:27 I:50 73.0 0.471 H -68.0 -45.5 NA NA NA
VAL M:27 M:50 73.0 0.471 H -66.7 -45.4 NA NA NA
VAL Q:27 Q:50 72.0 0.465 H -68.4 -44.6 NA NA NA
VAL U:27 U:50 73.0 0.471 H -68.6 -44.1 NA NA NA
VAL Y:27 Y:50 73.0 0.471 H -68.2 -44.9 NA NA NA
VAL CA:27 c:50 72.0 0.465 H -67.9 -45.3 NA NA NA
3fii 2 P63027 100.0 5e-14 X-RAY
 2009-06-23 VAL B:24 B:50 45.0 0.29 H -52.8 -45.3 32.0 0.206 0.084 A:Q57236:0.084
 HOH
 3.244
 CG1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p63027-f1 1 P63027 100.0 9e-83 VAL A:50 A:50 72.0 0.465 H -68.3 -43.3
af-q15836-f1 1 Q15836 86.42 5e-44 VAL A:33 A:33 72.0 0.465 H -65.9 -45.0