Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18232096 . G A CCDS11196.1:NM_004169.3:c.1420Ctc>Ttc_NP_004160.3:p.474L>F Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 LEU A:494 A:474 125.0 0.735 T -70.8 -15.3 125.0 0.735 0.0
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 LEU A:464 A:474 127.0 0.747 T -61.7 -14.3 127.0 0.747 0.0
LEU B:464 D:474 125.0 0.735 T -77.1 -8.3 125.0 0.735 0.0
LEU C:464 G:474 124.0 0.729 T -80.9 -6.2 124.0 0.729 0.0
LEU D:464 J:474 126.0 0.741 T -74.1 -7.5 126.0 0.741 0.0
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 LEU A:464 A:474 129.0 0.759 T -75.3 -12.1 129.0 0.759 0.0 HOH
 4.208
 O
 O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 LEU A:474 A:418 126.0 0.741 T -92.5 -5.8 126.0 0.741 0.0 HOH
 4.031
 CA
 O
LEU B:474 B:418 127.0 0.747 T -76.6 -10.1 127.0 0.747 0.0 HOH
 2.537
 O
 O
LEU C:474 C:418 76.0 NA T -79.7 3.3 76.0 NA NA HOH
 4.278
 N
 O
LEU D:474 D:418 126.0 0.741 T -64.1 -17.3 126.0 0.741 0.0 HOH
 6.748
 C
 O
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 LEU A:474 A:475 125.0 0.735 T -72.4 -17.1 125.0 0.735 0.0 HOH
 9.664
 N
 O
LEU B:474 B:475 127.0 0.747 T -71.6 -16.9 127.0 0.747 0.0 HOH
 9.479
 N
 O
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 LEU A:474 A:475 130.0 0.765 T -62.0 -24.1 130.0 0.765 0.0 HOH
 9.987
 N
 O
LEU B:474 B:475 131.0 0.771 T -63.0 -24.4 131.0 0.771 0.0 HOH
 9.613
 N
 O
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 LEU A:474 A:475 129.0 0.759 T -72.6 -13.6 129.0 0.759 0.0 HOH
 9.723
 N
 O
LEU B:474 B:475 128.0 0.753 T -72.5 -14.1 128.0 0.753 0.0 HOH
 9.647
 N
 O
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 LEU A:474 A:475 136.0 0.8 T -68.1 -16.2 136.0 0.8 0.0 HOH
 9.881
 N
 O
LEU B:474 B:475 138.0 0.812 T -68.6 -16.0 138.0 0.812 0.0 HOH
 9.750
 N
 O
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 LEU A:461 A:4181 77.0 NA H -68.8 -44.9 77.0 NA NA HOH
 8.259
 CB
 O
LEU B:461 B:4181 135.0 0.794 T -67.7 -3.7 135.0 0.794 0.0
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 ASN A:469 A:475 122.0 0.762 T -86.0 1.9 122.0 0.762 0.0
ASN B:469 B:475 122.0 0.762 T -86.2 2.2 122.0 0.762 0.0
ASN C:469 C:475 124.0 0.775 T -86.6 1.8 124.0 0.775 0.0
ASN D:469 D:475 123.0 0.769 T -85.9 2.1 123.0 0.769 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 LEU A:474 A:474 133.0 0.782 T -71.5 -18.9