Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18232123 . G A CCDS11196.1:NM_004169.3:c.1393Cgg>Tgg_NP_004160.3:p.465R>W Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 ARG A:485 A:465 66.0 0.293 H -68.2 -42.9 66.0 0.293 0.0
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 ARG A:455 A:465 120.0 0.533 H -49.9 -54.3 113.0 0.502 0.031 B:P34896:0.031
ARG B:455 D:465 121.0 0.538 H -44.8 -52.3 114.0 0.507 0.031 A:P34896:0.031
ARG C:455 G:465 124.0 0.551 H -44.1 -55.0 117.0 0.52 0.031 D:P34896:0.031
ARG D:455 J:465 121.0 0.538 H -55.9 -49.8 115.0 0.511 0.027 C:P34896:0.027
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 ARG A:455 A:465 121.0 0.538 H -58.2 -47.6 121.0 0.538 0.0 HOH
 3.384
 CZ
 O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 ARG A:465 A:412 116.0 0.516 H -33.0 -50.4 116.0 0.516 0.0 HOH
 6.878
 NH2
 O
ARG B:465 B:412 115.0 0.511 H -53.2 -44.1 115.0 0.511 0.0 HOH
 4.013
 NH1
 O
ARG C:465 C:412 124.0 0.551 H -52.2 -49.9 124.0 0.551 0.0 HOH
 6.843
 NH2
 O
ARG D:465 D:412 113.0 0.502 H -51.7 -41.2 113.0 0.502 0.0 HOH
 4.070
 CG
 O
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:465 A:466 116.0 0.516 H -57.9 -45.7 116.0 0.516 0.0
ARG B:465 B:466 118.0 0.524 H -57.8 -45.3 118.0 0.524 0.0
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:465 A:466 120.0 0.533 H -60.9 -43.9 120.0 0.533 0.0
ARG B:465 B:466 122.0 0.542 H -61.5 -43.7 122.0 0.542 0.0
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:465 A:466 109.0 0.484 H -57.5 -45.4 109.0 0.484 0.0
ARG B:465 B:466 118.0 0.524 H -56.4 -46.7 118.0 0.524 0.0
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:465 A:466 106.0 0.471 H -54.6 -46.8 106.0 0.471 0.0
ARG B:465 B:466 116.0 0.516 H -54.0 -46.1 116.0 0.516 0.0
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 ARG A:452 A:412 89.0 0.396 H -74.2 -56.3 89.0 0.396 0.0
ARG B:452 B:412 81.0 0.36 H -63.8 -52.8 81.0 0.36 0.0
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 ARG A:460 A:466 74.0 0.329 H -54.1 -42.5 74.0 0.329 0.0
ARG B:460 B:466 76.0 0.338 H -53.8 -42.4 76.0 0.338 0.0
ARG C:460 C:466 78.0 0.347 H -53.4 -43.1 78.0 0.347 0.0
ARG D:460 D:466 74.0 0.329 H -53.3 -43.2 74.0 0.329 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 ARG A:465 A:465 67.0 0.298 H -58.1 -47.4