Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18232135 . C A CCDS11196.1:NM_004169.3:c.1381Gtg>Ttg_NP_004160.3:p.461V>L Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 VAL A:481 A:461 0.0 0.0 H -63.9 -47.0 0.0 0.0 0.0
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 VAL A:451 A:461 17.0 0.11 H -56.6 -52.2 17.0 0.11 0.0
VAL B:451 D:461 16.0 0.103 H -52.5 -55.0 16.0 0.103 0.0
VAL C:451 G:461 15.0 0.097 H -56.3 -52.9 15.0 0.097 0.0
VAL D:451 J:461 17.0 0.11 H -61.5 -52.8 17.0 0.11 0.0
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 VAL A:451 A:461 17.0 0.11 H -61.0 -50.0 17.0 0.11 0.0 HOH
 7.549
 CG1
 O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 VAL A:461 A:409 10.0 0.065 H -66.3 -42.4 10.0 0.065 0.0 HOH
 6.738
 N
 O
VAL B:461 B:409 8.0 0.052 H -51.7 -42.8 8.0 0.052 0.0 HOH
 7.592
 CG1
 O
VAL C:461 C:409 15.0 0.097 H -63.8 -35.4 15.0 0.097 0.0 HOH
 7.073
 N
 O
VAL D:461 D:409 1.0 0.006 H -50.5 -45.9 1.0 0.006 0.0 HOH
 5.236
 O
 O
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 VAL A:461 A:462 4.0 0.026 H -61.1 -53.0 4.0 0.026 0.0
VAL B:461 B:462 4.0 0.026 H -60.4 -53.4 4.0 0.026 0.0
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 VAL A:461 A:462 6.0 0.039 H -52.5 -50.7 6.0 0.039 0.0
VAL B:461 B:462 6.0 0.039 H -52.7 -51.6 6.0 0.039 0.0
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 VAL A:461 A:462 3.0 0.019 H -58.4 -54.2 3.0 0.019 0.0
VAL B:461 B:462 6.0 0.039 H -58.0 -55.0 6.0 0.039 0.0
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 VAL A:461 A:462 1.0 0.006 H -54.3 -59.9 1.0 0.006 0.0
VAL B:461 B:462 5.0 0.032 H -54.5 -61.0 5.0 0.032 0.0
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 VAL A:448 A:409 0.0 0.0 H -52.5 -56.5 0.0 0.0 0.0
VAL B:448 B:409 2.0 0.013 H -54.2 -46.7 2.0 0.013 0.0
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 VAL A:456 A:462 7.0 0.045 H -57.8 -49.5 7.0 0.045 0.0
VAL B:456 B:462 1.0 0.006 H -57.4 -49.2 1.0 0.006 0.0
VAL C:456 C:462 5.0 0.032 H -57.6 -49.6 5.0 0.032 0.0
VAL D:456 D:462 12.0 0.077 H -57.6 -49.1 12.0 0.077 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 VAL A:461 A:461 0.0 0.0 H -60.1 -48.2