Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18232153 . C A CCDS11196.1:NM_004169.3:c.1363Gat>Tat_NP_004160.3:p.455D>Y Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 ASP A:475 A:455 149.0 0.993 H -79.3 -30.1 149.0 0.993 0.0
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 ASP A:445 A:455 137.0 0.913 S -81.9 -26.8 137.0 0.913 0.0
ASP B:445 D:455 139.0 0.927 S -82.7 -27.4 139.0 0.927 0.0
ASP C:445 G:455 169.0 1.0 S -94.4 -12.3 169.0 1.0 0.0
ASP D:445 J:455 139.0 0.927 S -77.1 -28.2 139.0 0.927 0.0
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 ASP A:445 A:455 137.0 0.913 S -74.9 -33.5 137.0 0.913 0.0
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 ASP A:454 A:404 108.0 0.72 S -133.8 139.5 108.0 0.72 0.0 HOH
 2.595
 OD1
 O
ASP B:454 B:404 65.0 NA 360.0 154.7 65.0 NA NA
ASP C:454 C:404 53.0 0.353 -171.2 117.4 53.0 0.353 0.0 HOH
 2.914
 OD2
 O
ASP D:454 D:404 57.0 0.38 -49.7 87.5 57.0 0.38 0.0
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ASP A:454 A:455 16.0 0.107 -148.8 114.4 16.0 0.107 0.0
ASP B:454 B:455 34.0 0.227 -114.9 99.4 34.0 0.227 0.0
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ASP A:454 A:455 22.0 0.147 173.8 109.4 22.0 0.147 0.0
ASP B:454 B:455 36.0 0.24 -146.3 90.7 36.0 0.24 0.0
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ASP A:454 A:455 12.0 0.08 -152.5 126.3 12.0 0.08 0.0
ASP B:454 B:455 33.0 0.22 -133.6 95.8 33.0 0.22 0.0
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ASP A:454 A:455 13.0 0.087 -158.8 130.5 13.0 0.087 0.0
ASP B:454 B:455 28.0 0.187 -133.2 104.9 28.0 0.187 0.0
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 ASP A:441 A:4041 48.0 0.32 -65.1 104.6 48.0 0.32 0.0
ASP B:441 B:4041 65.0 0.433 -63.8 124.9 65.0 0.433 0.0
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 ASP A:449 A:455 58.0 0.387 49.4 -156.1 58.0 0.387 0.0
ASP B:449 B:455 107.0 0.713 S -86.1 55.8 107.0 0.713 0.0
ASP C:449 C:455 43.0 0.287 -173.2 26.3 43.0 0.287 0.0
ASP D:449 D:455 87.0 0.58 S -101.3 -86.3 87.0 0.58 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 ASP A:455 A:455 151.0 1.0 H -58.5 -31.7