Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18232630 . T A CCDS11196.1:NM_004169.3:c.1244gAa>gTa_NP_004160.3:p.415E>V Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 GLU A:435 A:415 72.0 0.379 H -47.3 -53.7 72.0 0.379 0.0
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 GLU A:405 A:415 64.0 0.337 H -47.3 -60.4 64.0 0.337 0.0
GLU B:405 D:415 61.0 0.321 H -49.1 -62.2 61.0 0.321 0.0
GLU C:405 G:415 63.0 0.332 H -44.4 -60.1 63.0 0.332 0.0
GLU D:405 J:415 64.0 0.337 H -43.4 -61.3 64.0 0.337 0.0
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 GLU A:405 A:415 67.0 0.353 H -49.2 -50.9 67.0 0.353 0.0 HOH
 9.817
 CG
 O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 GLU A:414 A:374 89.0 0.468 H -46.8 -55.6 89.0 0.468 0.0 HOH
 2.627
 OE2
 O
GLU B:414 B:374 77.0 0.405 H -48.6 -52.8 77.0 0.405 0.0 HOH
 2.413
 OE2
 O
GLU C:414 C:374 88.0 0.463 H -49.2 -48.8 88.0 0.463 0.0
GLU D:414 D:374 93.0 0.489 H -49.5 -55.2 93.0 0.489 0.0
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 GLU A:414 A:415 81.0 0.426 H -46.9 -50.2 81.0 0.426 0.0
GLU B:414 B:415 81.0 0.426 H -46.9 -50.2 81.0 0.426 0.0
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 GLU A:414 A:415 81.0 0.426 H -42.4 -54.6 81.0 0.426 0.0
GLU B:414 B:415 80.0 0.421 H -42.8 -54.0 80.0 0.421 0.0
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 GLU A:414 A:415 79.0 0.416 H -49.2 -48.2 79.0 0.416 0.0
GLU B:414 B:415 80.0 0.421 H -48.8 -48.6 80.0 0.421 0.0
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 GLU A:414 A:415 84.0 0.442 H -43.3 -47.7 84.0 0.442 0.0
GLU B:414 B:415 81.0 0.426 H -44.2 -48.2 81.0 0.426 0.0
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 GLU A:401 A:3742 80.0 0.421 H -31.4 -62.3 80.0 0.421 0.0 HOH
 6.600
 N
 O
GLU B:401 B:3742 81.0 0.426 H -36.6 -59.8 81.0 0.426 0.0 HOH
 8.562
 N
 O
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 GLU A:409 A:415 72.0 0.379 H -48.3 -55.3 72.0 0.379 0.0
GLU B:409 B:415 72.0 0.379 H -47.5 -56.4 72.0 0.379 0.0
GLU C:409 C:415 73.0 0.384 H -46.4 -56.7 73.0 0.384 0.0
GLU D:409 D:415 74.0 0.389 H -46.5 -56.7 63.0 0.332 0.057 C:P50431:0.058

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 GLU A:415 A:415 78.0 0.411 H -57.1 -42.3