Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18232693 . C A CCDS11196.1:NM_004169.3:c.1181aGc>aTc_NP_004160.3:p.394S>I Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 SER A:414 A:394 53.0 0.461 -163.4 136.0 53.0 0.461 0.0
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 SER A:384 A:394 45.0 0.391 -156.1 118.4 45.0 0.391 0.0
SER B:384 D:394 44.0 0.383 -161.8 117.1 44.0 0.383 0.0
SER C:384 G:394 47.0 0.409 -161.1 118.4 47.0 0.409 0.0
SER D:384 J:394 46.0 0.4 -160.4 118.5 46.0 0.4 0.0
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 SER A:384 A:394 49.0 0.426 -162.1 123.0 49.0 0.426 0.0 HOH
 7.913
 O
 O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 SER A:393 A:355 116.0 1.0 S 24.9 95.7 116.0 1.0 0.0 HOH
 3.821
 CA
 O
SER B:393 NA:NA DO NA DO DO DO NA NA NA
SER C:393 C:355 48.0 NA -126.0 151.5 48.0 NA NA HOH
 5.820
 CB
 O
SER D:393 D:355 55.0 0.478 T 21.3 107.8 55.0 0.478 0.0 TGF
HOH
 5.067
3.135
 O
N
 O12
O
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 SER A:393 A:394 57.0 0.496 -166.5 131.6 57.0 0.496 0.0
SER B:393 B:394 58.0 0.504 -167.0 131.3 58.0 0.504 0.0
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 SER A:393 A:394 56.0 0.487 -115.8 136.2 56.0 0.487 0.0
SER B:393 B:394 54.0 0.47 -115.8 136.0 54.0 0.47 0.0
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 SER A:393 A:394 56.0 0.487 -164.6 132.4 56.0 0.487 0.0
SER B:393 B:394 58.0 0.504 -164.7 132.3 58.0 0.504 0.0
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 SER A:393 A:394 53.0 0.461 -152.8 136.1 53.0 0.461 0.0
SER B:393 B:394 55.0 0.478 -152.9 136.1 55.0 0.478 0.0
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 SER A:380 A:355 46.0 NA 138.0 104.4 46.0 NA NA
SER B:380 B:355 52.0 NA 136.3 104.6 52.0 NA NA
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 SER A:388 A:394 80.0 0.696 -178.9 153.6 80.0 0.696 0.0 THF
HOH
 5.598
3.210
 CB
OG
 O2
O
SER B:388 B:394 68.0 0.591 -93.4 -24.2 68.0 0.591 0.0 THF
HOH
 4.779
4.951
 O
N
 OE2
O
SER C:388 C:394 50.0 0.435 -12.0 -83.7 50.0 0.435 0.0 HOH
 9.558
 C
 O
SER D:388 D:394 75.0 0.652 103.3 155.3 75.0 0.652 0.0 THF
HOH
 9.514
8.288
 OG
O
 O
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 SER A:394 A:394 52.0 0.452 -151.0 128.7