Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18233950 . G A CCDS11196.1:NM_004169.3:c.1090Cgt>Tgt_NP_004160.3:p.364R>C Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 ARG A:384 A:364 102.0 0.453 G -65.6 -17.2 102.0 0.453 0.0
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 ARG A:354 A:364 97.0 0.431 G -56.6 -20.1 97.0 0.431 0.0
ARG B:354 D:364 98.0 0.436 G -56.9 -20.8 98.0 0.436 0.0
ARG C:354 G:364 100.0 0.444 G -61.0 -20.8 100.0 0.444 0.0
ARG D:354 J:364 103.0 0.458 G -59.4 -21.8 103.0 0.458 0.0
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 ARG A:354 A:364 97.0 0.431 G -64.0 -22.6 97.0 0.431 0.0 HOH
 7.195
 CG
 O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 ARG A:363 A:324 117.0 0.52 G -66.3 -34.0 117.0 0.52 0.0 HOH
 3.995
 NH1
 O
ARG B:363 B:324 75.0 NA 46.1 360.0 75.0 NA NA HOH
 4.145
 C
 O
ARG C:363 C:324 117.0 0.52 G -56.1 -34.9 117.0 0.52 0.0 HOH
 3.314
 CZ
 O
ARG D:363 D:324 125.0 0.556 T 63.8 -17.5 125.0 0.556 0.0 HOH
 6.280
 NH2
 O
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:363 A:364 111.0 0.493 G -62.2 -27.9 111.0 0.493 0.0
ARG B:363 B:364 112.0 0.498 G -62.8 -28.0 112.0 0.498 0.0
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:363 A:364 108.0 0.48 G -60.1 -34.3 108.0 0.48 0.0
ARG B:363 B:364 107.0 0.476 G -60.0 -35.3 107.0 0.476 0.0
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:363 A:364 113.0 0.502 G -63.3 -26.8 113.0 0.502 0.0
ARG B:363 B:364 115.0 0.511 G -63.6 -27.8 115.0 0.511 0.0
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:363 A:364 106.0 0.471 G -63.8 -34.6 106.0 0.471 0.0
ARG B:363 B:364 108.0 0.48 G -64.5 -35.6 108.0 0.48 0.0
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 ARG A:350 A:324 113.0 0.502 G -73.4 -24.9 113.0 0.502 0.0
ARG B:350 B:324 110.0 0.489 G -77.4 -27.1 110.0 0.489 0.0
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 ARG A:358 A:364 129.0 0.573 G -47.7 -39.1 129.0 0.573 0.0
ARG B:358 B:364 90.0 0.4 G -48.1 -39.8 90.0 0.4 0.0 HOH
 3.972
 NH2
 O
ARG C:358 C:364 92.0 0.409 G -46.7 -39.9 92.0 0.409 0.0
ARG D:358 D:364 96.0 0.427 G -47.3 -39.9 96.0 0.427 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 ARG A:364 A:364 96.0 0.427 G -55.2 -36.5