Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18236488 . A C CCDS11196.1:NM_004169.3:c.1046aTa>aGa_NP_004160.3:p.349I>R Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 ILE A:369 A:349 5.0 0.029 E -90.3 117.2 5.0 0.029 0.0
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 ILE A:339 A:349 9.0 0.051 E -80.8 131.1 9.0 0.051 0.0
ILE B:339 D:349 10.0 0.057 E -77.0 132.6 10.0 0.057 0.0
ILE C:339 G:349 9.0 0.051 E -88.8 125.2 9.0 0.051 0.0
ILE D:339 J:349 10.0 0.057 E -90.3 126.8 10.0 0.057 0.0
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 ILE A:339 A:349 7.0 0.04 E -101.2 123.9 7.0 0.04 0.0 HOH
 3.960
 CG2
 O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 ILE A:348 A:309 4.0 0.023 E -109.9 128.9 4.0 0.023 0.0
ILE B:348 B:309 14.0 0.08 E -106.2 117.2 14.0 0.08 0.0 HOH
 7.069
 CG1
 O
ILE C:348 C:309 12.0 0.069 E -123.1 122.6 12.0 0.069 0.0 HOH
 4.113
 O
 O
ILE D:348 D:309 10.0 0.057 E -103.6 118.7 10.0 0.057 0.0
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ILE A:348 A:349 3.0 0.017 E -100.4 126.7 3.0 0.017 0.0 HOH
 4.298
 CG2
 O
ILE B:348 B:349 3.0 0.017 E -102.2 132.2 3.0 0.017 0.0 HOH
 3.708
 CG2
 O
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ILE A:348 A:349 3.0 0.017 E -103.1 121.1 3.0 0.017 0.0 HOH
 4.367
 CG2
 O
ILE B:348 B:349 4.0 0.023 E -104.2 124.4 4.0 0.023 0.0 HOH
 3.694
 CG2
 O
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ILE A:348 A:349 3.0 0.017 E -105.9 128.3 3.0 0.017 0.0 HOH
 3.950
 CG2
 O
ILE B:348 B:349 2.0 0.011 E -109.9 133.3 2.0 0.011 0.0 HOH
 3.727
 CG2
 O
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ILE A:348 A:349 5.0 0.029 E -95.2 129.0 5.0 0.029 0.0 HOH
 4.071
 CG2
 O
ILE B:348 B:349 2.0 0.011 E -97.9 130.4 2.0 0.011 0.0 HOH
 3.769
 CG2
 O
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 ILE A:335 A:309 1.0 0.006 E -97.0 138.2 1.0 0.006 0.0
ILE B:335 B:309 10.0 0.057 E -88.0 134.2 10.0 0.057 0.0
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 ILE A:343 A:349 9.0 0.051 B -109.6 110.9 9.0 0.051 0.0
ILE B:343 B:349 8.0 0.046 B -108.5 110.4 8.0 0.046 0.0
ILE C:343 C:349 9.0 0.051 B -108.8 110.8 9.0 0.051 0.0
ILE D:343 D:349 8.0 0.046 B -108.3 110.8 8.0 0.046 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 ILE A:349 A:349 11.0 0.063 E -96.1 127.9