Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18243453 . C A CCDS11196.1:NM_004169.3:c.718Gtg>Ttg_NP_004160.3:p.240V>L Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 VAL A:260 A:240 29.0 0.187 S -78.4 -3.2 29.0 0.187 0.0
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 VAL A:230 A:240 33.0 0.213 S -83.0 -22.4 33.0 0.213 0.0
VAL B:230 D:240 31.0 0.2 S -78.9 -17.7 31.0 0.2 0.0
VAL C:230 G:240 32.0 0.206 S -76.3 -23.2 32.0 0.206 0.0
VAL D:230 J:240 31.0 0.2 S -76.4 -27.7 31.0 0.2 0.0
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 VAL A:230 A:240 27.0 0.174 S -71.0 -14.4 27.0 0.174 0.0 HOH
 3.884
 O
 O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 VAL A:239 A:212 45.0 0.29 S -103.3 1.0 45.0 0.29 0.0 HOH
 6.233
 C
 O
VAL B:239 B:212 42.0 0.271 S -101.4 -0.2 42.0 0.271 0.0 GOL
HOH
 9.231
3.713
 O
C
 O1
O
VAL C:239 C:212 47.0 0.303 S -104.0 0.7 47.0 0.303 0.0 HOH
 6.038
 C
 O
VAL D:239 D:212 43.0 0.277 S -96.5 -2.2 43.0 0.277 0.0 GOL
HOH
 9.505
3.640
 O
C
 O2
O
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 VAL A:239 A:240 41.0 0.265 S -86.7 -15.4 41.0 0.265 0.0 HOH
 6.642
 C
 O
VAL B:239 B:240 41.0 0.265 S -86.0 -15.9 41.0 0.265 0.0 HOH
 9.315
 C
 O
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 VAL A:239 A:240 43.0 0.277 S -84.7 -17.1 43.0 0.277 0.0 HOH
 6.466
 C
 O
VAL B:239 B:240 43.0 0.277 S -85.6 -16.3 43.0 0.277 0.0 HOH
 9.366
 O
 O
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 VAL A:239 A:240 42.0 0.271 S -89.0 -16.6 42.0 0.271 0.0 HOH
 9.376
 C
 O
VAL B:239 B:240 42.0 0.271 S -88.6 -16.9 42.0 0.271 0.0 HOH
 9.225
 C
 O
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 VAL A:239 A:240 43.0 0.277 S -82.4 -16.0 43.0 0.277 0.0 HOH
 9.413
 C
 O
VAL B:239 B:240 42.0 0.271 S -81.8 -17.1 42.0 0.271 0.0 HOH
 9.365
 C
 O
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 VAL A:226 A:212 49.0 0.316 S -60.3 -51.7 49.0 0.316 0.0
VAL B:226 B:212 51.0 0.329 S -67.4 -51.0 51.0 0.329 0.0
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 VAL A:234 A:240 33.0 0.213 S -67.9 -17.8 33.0 0.213 0.0
VAL B:234 B:240 33.0 0.213 S -67.5 -18.3 33.0 0.213 0.0
VAL C:234 C:240 33.0 0.213 S -67.8 -18.2 33.0 0.213 0.0
VAL D:234 D:240 34.0 0.219 S -68.1 -18.4 34.0 0.219 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 VAL A:240 A:240 35.0 0.226 S -90.5 -21.8