Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18243495 . T A CCDS11196.1:NM_004169.3:c.676Atg>Ttg_NP_004160.3:p.226M>L Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 MET A:246 A:226 1.0 0.005 E -116.8 132.4 1.0 0.005 0.0 PLP
 7.791
 CE
 N1
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 MET A:216 A:226 0.0 0.0 E -104.1 122.9 0.0 0.0 0.0 PLP
 7.668
 CE
 N1
MET B:216 D:226 0.0 0.0 E -102.0 127.9 0.0 0.0 0.0 PLP
 7.543
 CE
 N1
MET C:216 G:226 0.0 0.0 E -104.3 120.0 0.0 0.0 0.0 PLP
 7.671
 CE
 N1
MET D:216 J:226 1.0 0.005 E -99.2 126.7 1.0 0.005 0.0 PLP
 7.542
 CE
 N1
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 MET A:216 A:226 0.0 0.0 E -108.7 124.6 0.0 0.0 0.0 PLP
HOH
 7.250
6.784
 CE
O
 N1
O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 MET A:225 A:198 1.0 0.005 E -103.0 124.6 1.0 0.005 0.0 PLP
HOH
 7.462
6.278
 CE
O
 N1
O
MET B:225 B:198 0.0 0.0 E -98.1 126.7 0.0 0.0 0.0 PLP
HOH
 7.670
9.197
 CE
O
 N1
O
MET C:225 C:198 0.0 0.0 E -102.1 125.1 0.0 0.0 0.0 PLP
HOH
 7.522
6.224
 CE
CE
 N1
O
MET D:225 D:198 1.0 0.005 E -96.9 125.8 1.0 0.005 0.0 PLP
HOH
 7.671
9.755
 CE
N
 N1
O
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 MET A:225 A:226 0.0 0.0 E -110.4 128.4 0.0 0.0 0.0 PLP
HOH
 7.474
6.393
 CE
O
 N1
O
MET B:225 B:226 0.0 0.0 E -110.1 128.1 0.0 0.0 0.0 PLP
HOH
 7.482
6.602
 CE
O
 N1
O
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 MET A:225 A:226 1.0 0.005 E -102.8 127.6 1.0 0.005 0.0 PLG
HOH
 7.302
6.152
 CE
O
 N1
O
MET B:225 B:226 0.0 0.0 E -104.0 128.2 0.0 0.0 0.0 PLP
HOH
 7.663
6.479
 CE
O
 C2A
O
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 MET A:225 A:226 1.0 0.005 E -115.3 128.2 1.0 0.005 0.0 PLP
HOH
 7.835
6.251
 CE
O
 N1
O
MET B:225 B:226 0.0 0.0 E -114.3 127.7 0.0 0.0 0.0 PLP
HOH
 7.719
6.364
 CE
O
 N1
O
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 MET A:225 A:226 1.0 0.005 E -107.0 135.6 1.0 0.005 0.0 PLP
HOH
 7.710
6.315
 CE
O
 N1
O
MET B:225 B:226 0.0 0.0 E -106.6 135.2 0.0 0.0 0.0 PLP
HOH
 7.746
6.378
 CE
O
 N1
O
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 MET A:212 A:198 0.0 0.0 E -115.4 124.1 0.0 0.0 0.0 PLP
 7.732
 CE
 N1
MET B:212 B:198 0.0 0.0 E -111.1 126.4 0.0 0.0 0.0 PLP
HOH
 7.867
6.745
 CE
O
 N1
O
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 MSE A:220 A:226 1.0 0.005 E -116.2 130.1 1.0 0.005 0.0 PLG
 7.234
 CE
 N1
MSE B:220 B:226 1.0 0.005 E -115.3 129.9 1.0 0.005 0.0 PLG
 7.367
 CE
 N1
MSE C:220 C:226 1.0 0.005 E -114.8 130.2 1.0 0.005 0.0 PLG
HOH
 7.255
6.714
 CE
O
 N1
O
MSE D:220 D:226 1.0 0.005 E -114.3 128.9 1.0 0.005 0.0 PLG
 7.195
 CE
 N1

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 MET A:226 A:226 0.0 0.0 E -113.4 120.2