Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18243524 . T A CCDS11196.1:NM_004169.3:c.647aAg>aTg_NP_004160.3:p.216K>M Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 LYS A:236 A:216 98.0 0.49 H -61.9 -44.0 98.0 0.49 0.0
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 LYS A:206 A:216 123.0 0.615 H -57.0 -48.7 123.0 0.615 0.0
LYS B:206 D:216 102.0 0.51 H -57.5 -42.2 102.0 0.51 0.0
LYS C:206 G:216 127.0 0.635 H -52.4 -45.2 127.0 0.635 0.0
LYS D:206 J:216 126.0 0.63 H -56.6 -44.1 126.0 0.63 0.0
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 LYS A:206 A:216 127.0 0.635 H -63.5 -47.8 127.0 0.635 0.0 HOH
 6.208
 O
 O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 LYS A:215 A:188 149.0 0.745 H -67.4 -45.0 149.0 0.745 0.0 HOH
 4.050
 CG
 O
LYS B:215 B:188 54.0 NA H -62.0 -28.6 54.0 NA NA HOH
 8.692
 O
 O
LYS C:215 C:188 151.0 0.755 H -67.2 -43.1 151.0 0.755 0.0 HOH
 3.777
 CG
 O
LYS D:215 D:188 56.0 NA H -61.9 -28.4 56.0 NA NA
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 LYS A:215 A:216 139.0 0.695 H -60.2 -49.1 139.0 0.695 0.0 HOH
 5.834
 O
 O
LYS B:215 B:216 140.0 0.7 H -60.9 -48.7 140.0 0.7 0.0
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 LYS A:215 A:216 141.0 0.705 H -60.8 -47.1 141.0 0.705 0.0 HOH
 6.168
 O
 O
LYS B:215 B:216 143.0 0.715 H -62.0 -45.4 143.0 0.715 0.0
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 LYS A:215 A:216 151.0 0.755 H -63.6 -42.5 151.0 0.755 0.0
LYS B:215 B:216 142.0 0.71 H -62.9 -43.7 142.0 0.71 0.0
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 LYS A:215 A:216 152.0 0.76 H -65.0 -37.3 152.0 0.76 0.0
LYS B:215 B:216 142.0 0.71 H -63.8 -38.5 142.0 0.71 0.0
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 LYS A:202 A:188 117.0 0.585 H -62.1 -58.2 117.0 0.585 0.0
LYS B:202 B:188 53.0 NA H -71.2 -28.2 53.0 NA NA
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 LYS A:210 A:216 93.0 0.465 H -57.5 -55.5 93.0 0.465 0.0
LYS B:210 B:216 92.0 0.46 H -57.9 -54.4 92.0 0.46 0.0
LYS C:210 C:216 90.0 0.45 H -57.5 -55.4 90.0 0.45 0.0
LYS D:210 D:216 94.0 0.47 H -57.4 -54.5 94.0 0.47 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 LYS A:216 A:216 95.0 0.475 H -55.8 -48.3