Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18243534 . G A CCDS11196.1:NM_004169.3:c.637Cgg>Tgg_NP_004160.3:p.213R>W Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 ARG A:233 A:213 51.0 0.227 H -79.7 -32.2 51.0 0.227 0.0
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 ARG A:203 A:213 53.0 0.236 H -56.2 -52.3 53.0 0.236 0.0
ARG B:203 D:213 55.0 0.244 H -64.8 -53.1 55.0 0.244 0.0
ARG C:203 G:213 52.0 0.231 H -53.8 -50.3 52.0 0.231 0.0
ARG D:203 J:213 49.0 0.218 H -59.3 -55.1 49.0 0.218 0.0
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 ARG A:203 A:213 48.0 0.213 H -68.6 -42.8 48.0 0.213 0.0 HOH
 4.030
 N
 O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 ARG A:212 A:185 58.0 0.258 H -72.4 -45.6 58.0 0.258 0.0 HOH
 3.011
 NH1
 O
ARG B:212 B:185 64.0 0.284 H -70.0 -43.0 64.0 0.284 0.0 GOL
HOH
 6.595
7.191
 N
NH1
 O2
O
ARG C:212 C:185 58.0 0.258 H -68.3 -46.8 58.0 0.258 0.0 GOL
HOH
 4.523
2.626
 NH2
NH1
 O1
O
ARG D:212 D:185 60.0 0.267 H -68.3 -43.6 60.0 0.267 0.0 GOL
HOH
 6.385
5.179
 N
NH1
 O1
O
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:212 A:213 45.0 0.2 H -63.5 -44.7 45.0 0.2 0.0 HOH
 6.982
 NH1
 O
ARG B:212 B:213 44.0 0.196 H -62.5 -44.8 44.0 0.196 0.0 HOH
 8.697
 CB
 O
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:212 A:213 46.0 0.204 H -65.7 -56.9 46.0 0.204 0.0 HOH
 7.542
 NH1
 O
ARG B:212 B:213 45.0 0.2 H -65.3 -56.9 45.0 0.2 0.0 HOH
 8.563
 CB
 O
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:212 A:213 54.0 0.24 H -64.8 -42.4 54.0 0.24 0.0 HOH
 8.552
 CB
 O
ARG B:212 B:213 52.0 0.231 H -63.6 -42.7 52.0 0.231 0.0 HOH
 8.702
 CB
 O
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:212 A:213 59.0 0.262 H -69.8 -46.3 59.0 0.262 0.0 HOH
 8.639
 CB
 O
ARG B:212 B:213 51.0 0.227 H -70.8 -45.4 51.0 0.227 0.0 HOH
 8.819
 CB
 O
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 ARG A:199 A:185 52.0 0.231 H -67.8 -40.7 52.0 0.231 0.0 HOH
 9.657
 NH2
 O
ARG B:199 B:185 63.0 0.28 H -66.7 -37.3 63.0 0.28 0.0
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 ARG A:207 A:213 57.0 0.253 H -69.9 -40.4 57.0 0.253 0.0
ARG B:207 B:213 56.0 0.249 H -68.5 -40.5 56.0 0.249 0.0
ARG C:207 C:213 55.0 0.244 H -70.8 -40.5 55.0 0.244 0.0
ARG D:207 D:213 59.0 0.262 H -71.9 -38.5 59.0 0.262 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 ARG A:213 A:213 51.0 0.227 H -64.4 -44.5