Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18243561 . A C CCDS11196.1:NM_004169.3:c.610Tgc>Ggc_NP_004160.3:p.204C>G Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 CYS A:224 A:204 8.0 0.059 S -158.2 68.9 8.0 0.059 0.0 PLP
DXC
GLY
 6.252
6.293
6.515
 N
CB
N
 C2A
C24
O
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 CYS A:194 A:204 7.0 0.052 S -133.4 69.4 7.0 0.052 0.0 PLP
CL
 6.275
6.814
 N
N
 O3
CL
CYS B:194 D:204 6.0 0.044 S -128.3 71.1 6.0 0.044 0.0 CL
PLP
 6.857
6.196
 N
N
 CL
O3
CYS C:194 G:204 8.0 0.059 S -134.7 70.8 8.0 0.059 0.0 PLP
CL
 6.500
7.074
 N
N
 O3
CL
CYS D:194 J:204 6.0 0.044 S -139.0 66.1 6.0 0.044 0.0 CL
PLP
 7.225
6.363
 N
N
 CL
O3
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 CYS A:194 A:204 6.0 0.044 S -142.3 77.9 6.0 0.044 0.0 PLP
HOH
 6.601
3.180
 N
N
 O3
O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 CYS A:203 A:176 5.0 0.037 S -150.7 72.0 5.0 0.037 0.0 PLP
GLY
HOH
 6.551
5.574
6.452
 N
N
CB
 O3
O
O
CYS B:203 B:176 19.0 0.141 S -153.9 78.8 19.0 0.141 0.0 PLP
TGF
HOH
 6.260
3.706
6.935
 N
CB
N
 O3
NA2
O
CYS C:203 C:176 5.0 0.037 S -148.3 75.6 5.0 0.037 0.0 GLY
PLP
HOH
 6.607
6.431
5.322
 N
N
O
 CA
O3
O
CYS D:203 D:176 5.0 0.037 S -148.6 75.4 5.0 0.037 0.0 PLP
TGF
HOH
 6.365
3.158
7.143
 N
CB
SG
 O3
NA2
O
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 CYS A:203 A:204 4.0 0.03 S -150.2 74.7 4.0 0.03 0.0 PLP
HOH
 6.654
2.916
 N
N
 O3
O
CYS B:203 B:204 6.0 0.044 S -149.3 75.8 6.0 0.044 0.0 PO4
PLP
HOH
 5.995
6.666
3.491
 N
N
N
 O1
O3
O
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 CYS A:203 A:204 6.0 0.044 S -154.1 73.7 6.0 0.044 0.0 PLG
HOH
 6.284
2.901
 N
N
 O
O
CYS B:203 B:204 6.0 0.044 S -153.9 75.6 6.0 0.044 0.0 PO4
PLP
HOH
 6.517
6.546
3.004
 N
N
N
 O1
O3
O
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 CYS A:203 A:204 7.0 0.052 S -152.0 69.9 7.0 0.052 0.0 PO4
PLP
HOH
 6.193
6.482
2.887
 N
N
N
 O1
O3
O
CYS B:203 B:204 7.0 0.052 S -152.3 70.9 7.0 0.052 0.0 PO4
GLY
PLP
HOH
 5.714
5.838
6.675
3.067
 N
N
N
N
 O1
OXT
O3
O
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 CYS A:203 A:204 5.0 0.037 S -145.1 65.0 5.0 0.037 0.0 PO4
PLP
HOH
 5.897
6.615
3.280
 N
N
N
 O1
O3
O
CYS B:203 B:204 7.0 0.052 S -146.1 64.7 7.0 0.052 0.0 PO4
PLP
HOH
 6.082
6.807
3.328
 N
N
N
 O1
O3
O
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 CYS A:190 A:176 7.0 0.052 S -155.0 80.6 7.0 0.052 0.0 PLP
HOH
 6.706
6.690
 N
N
 O3
O
CYS B:190 B:176 7.0 0.052 S -155.5 82.5 7.0 0.052 0.0 PLP
HOH
 6.647
7.096
 N
N
 O3
O
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 CYS A:198 A:204 9.0 0.067 S -153.5 66.9 9.0 0.067 0.0 PLG
THF
HOH
 6.229
3.610
7.175
 N
CB
SG
 OXT
NA2
O
CYS B:198 B:204 9.0 0.067 S -153.6 66.2 9.0 0.067 0.0 PLG
THF
HOH
 6.118
3.273
7.349
 N
CB
CB
 OXT
NA2
O
CYS C:198 C:204 10.0 0.074 S -154.5 68.0 10.0 0.074 0.0 PLG
HOH
 6.495
5.187
 N
CB
 O3
O
CYS D:198 D:204 8.0 0.059 S -153.9 66.8 8.0 0.059 0.0 PLG
THF
HOH
 6.498
3.622
5.095
 N
CB
SG
 O3
NA2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 CYS A:204 A:204 6.0 0.044 S -143.2 71.1