Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18244057 . A C CCDS11196.1:NM_004169.3:c.590cTg>cGg_NP_004160.3:p.197L>R Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 LEU A:217 A:197 0.0 0.0 E -154.3 127.7 0.0 0.0 0.0
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 LEU A:187 A:197 0.0 0.0 E -166.4 132.7 0.0 0.0 0.0
LEU B:187 D:197 0.0 0.0 E -146.1 136.2 0.0 0.0 0.0
LEU C:187 G:197 0.0 0.0 E -149.9 128.7 0.0 0.0 0.0
LEU D:187 J:197 0.0 0.0 E -146.9 129.8 0.0 0.0 0.0
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 LEU A:187 A:197 0.0 0.0 E -155.3 133.7 0.0 0.0 0.0 HOH
 6.538
 N
 O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 LEU A:196 A:169 0.0 0.0 E -152.0 133.7 0.0 0.0 0.0 HOH
 8.190
 CD2
 O
LEU B:196 B:169 0.0 0.0 E -147.4 137.1 0.0 0.0 0.0 HOH
 8.253
 N
 O
LEU C:196 C:169 0.0 0.0 E -151.7 134.6 0.0 0.0 0.0 HOH
 8.472
 CD2
 O
LEU D:196 D:169 0.0 0.0 E -147.8 139.0 0.0 0.0 0.0 HOH
 7.998
 O
 O
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 LEU A:196 A:197 0.0 0.0 E -152.3 134.5 0.0 0.0 0.0 HOH
 7.502
 N
 O
LEU B:196 B:197 0.0 0.0 E -153.0 134.3 0.0 0.0 0.0 HOH
 7.431
 N
 O
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 LEU A:196 A:197 0.0 0.0 E -156.1 128.2 0.0 0.0 0.0 HOH
 7.786
 N
 O
LEU B:196 B:197 0.0 0.0 E -156.6 130.1 0.0 0.0 0.0 HOH
 7.832
 N
 O
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 LEU A:196 A:197 0.0 0.0 E -154.9 136.7 0.0 0.0 0.0 HOH
 7.478
 N
 O
LEU B:196 B:197 0.0 0.0 E -154.2 136.7 0.0 0.0 0.0 HOH
 7.440
 N
 O
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 LEU A:196 A:197 0.0 0.0 E -158.0 131.8 0.0 0.0 0.0 HOH
 7.226
 N
 O
LEU B:196 B:197 0.0 0.0 E -158.3 133.4 0.0 0.0 0.0 HOH
 7.249
 N
 O
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 LEU A:183 A:169 0.0 0.0 E -156.9 134.5 0.0 0.0 0.0 HOH
 8.779
 CB
 O
LEU B:183 B:169 0.0 0.0 E -152.3 138.5 0.0 0.0 0.0
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 LEU A:191 A:197 1.0 0.006 E -157.3 139.6 1.0 0.006 0.0
LEU B:191 B:197 1.0 0.006 E -156.1 140.0 1.0 0.006 0.0
LEU C:191 C:197 0.0 0.0 E -155.6 140.5 0.0 0.0 0.0 HOH
 8.501
 CD2
 O
LEU D:191 D:197 0.0 0.0 E -155.4 141.2 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 LEU A:197 A:197 0.0 0.0 E -147.2 132.4