Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18250889 . C A CCDS11196.1:NM_004169.3:c.440gGc>gTc_NP_004160.3:p.147G>V Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 GLY A:167 A:147 0.0 0.0 -114.8 146.7 0.0 0.0 0.0 PLP
DXC
GLY
 6.338
5.445
7.035
 C
O
O
 C2A
C20
O
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 GLY A:137 A:147 5.0 0.067 -80.0 177.9 5.0 0.067 0.0 PLP
CL
 5.883
7.227
 C
O
 C2A
CL
GLY B:137 D:147 5.0 0.067 -79.0 -174.8 5.0 0.067 0.0 CL
PLP
 7.112
5.696
 O
C
 CL
C2A
GLY C:137 G:147 5.0 0.067 -81.5 -176.0 5.0 0.067 0.0 PLP
CL
 5.940
7.536
 C
O
 C2A
CL
GLY D:137 J:147 5.0 0.067 -79.8 -177.9 5.0 0.067 0.0 CL
PLP
 7.613
6.084
 O
C
 CL
C2A
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 GLY A:137 A:147 6.0 0.08 -84.2 176.1 6.0 0.08 0.0 PLP
HOH
 5.974
4.850
 C
O
 C2A
O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 GLY A:146 A:125 8.0 0.107 -77.6 177.7 8.0 0.107 0.0 PLP
GLY
HOH
 6.464
5.920
4.275
 C
O
O
 C2A
O
O
GLY B:146 B:125 8.0 0.107 -82.4 169.0 8.0 0.107 0.0 PLP
TGF
HOH
 6.342
2.581
5.432
 C
O
CA
 C2A
N3
O
GLY C:146 C:125 8.0 0.107 -77.6 175.0 8.0 0.107 0.0 GLY
PLP
HOH
 6.730
6.438
5.194
 O
C
CA
 OXT
C2A
O
GLY D:146 D:125 10.0 0.133 -83.2 168.4 10.0 0.133 0.0 PLP
TGF
HOH
 6.654
2.577
7.958
 C
O
CA
 C2A
N3
O
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 GLY A:146 A:147 8.0 0.107 -83.3 175.5 8.0 0.107 0.0 PLP
HOH
 6.574
5.616
 C
CA
 C2A
O
GLY B:146 B:147 9.0 0.12 -82.5 175.8 9.0 0.12 0.0 PO4
PLP
HOH
 6.660
6.728
5.134
 O
C
CA
 O1
C2A
O
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 GLY A:146 A:147 9.0 0.12 -91.3 174.3 9.0 0.12 0.0 PLG
HOH
 6.610
5.750
 C
CA
 C2A
O
GLY B:146 B:147 9.0 0.12 -91.4 175.0 9.0 0.12 0.0 PO4
PLP
HOH
 7.315
6.715
5.470
 O
C
CA
 O3
C2A
O
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 GLY A:146 A:147 9.0 0.12 -84.0 170.8 9.0 0.12 0.0 PO4
PLP
HOH
 6.316
6.653
5.238
 O
C
CA
 O1
C2A
O
GLY B:146 B:147 9.0 0.12 -85.2 171.7 9.0 0.12 0.0 PO4
GLY
PLP
HOH
 6.600
7.302
6.712
5.192
 O
O
C
CA
 O1
OXT
C2A
O
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 GLY A:146 A:147 9.0 0.12 -95.1 176.9 9.0 0.12 0.0 PO4
PLP
HOH
 6.462
6.670
5.404
 O
C
CA
 O1
C2A
O
GLY B:146 B:147 8.0 0.107 -95.1 176.8 8.0 0.107 0.0 PO4
PLP
HOH
 6.696
6.706
5.287
 O
C
CA
 O1
C2A
O
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 GLY A:133 A:125 4.0 0.053 -79.6 179.7 4.0 0.053 0.0 PLP
HOH
 6.363
6.987
 C
O
 C2A
O
GLY B:133 B:125 2.0 0.027 -83.7 -174.4 2.0 0.027 0.0 PLP
HOH
 6.547
7.630
 C
O
 C2A
O
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 GLY A:141 A:147 0.0 0.0 -75.1 179.8 0.0 0.0 0.0 PLG
THF
HOH
 6.432
2.899
9.637
 C
O
O
 C2A
N3
O
GLY B:141 B:147 0.0 0.0 -75.1 160.7 0.0 0.0 0.0 PLG
THF
HOH
 6.617
3.086
7.283
 C
O
O
 C2A
N3
O
GLY C:141 C:147 7.0 0.093 -77.7 170.2 7.0 0.093 0.0 PLG
HOH
 6.142
5.078
 C
CA
 C2A
O
GLY D:141 D:147 0.0 0.0 -92.6 -179.8 0.0 0.0 0.0 PLG
THF
HOH
 5.932
3.765
7.343
 C
O
O
 C2A
O4
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 GLY A:147 A:147 4.0 0.053 -66.1 -174.6