Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18250919 . C A CCDS11196.1:NM_004169.3:c.410cGc>cTc_NP_004160.3:p.137R>L Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
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auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 ARG A:157 A:137 105.0 0.467 E -81.3 139.0 4.0 0.018 0.449 A:P34896:0.449
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 ALA A:127 A:137 13.0 0.113 E -88.3 129.9 13.0 0.113 0.0
ALA B:127 D:137 13.0 0.113 E -111.4 121.1 12.0 0.104 0.009 D:P34896:0.009
ALA C:127 G:137 12.0 0.104 -64.8 139.7 11.0 0.096 0.008 A:P34896:0.009
ALA D:127 J:137 12.0 0.104 E -106.7 121.3 12.0 0.104 0.0
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 ARG A:127 A:137 106.0 0.471 E -84.6 136.3 106.0 0.471 0.0 HOH
 2.949
 N
 O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 ARG A:136 A:115 106.0 0.471 E -88.7 130.9 7.0 0.031 0.44 C:p07511:0.44
 HOH
 3.843
 NE
 O
ARG B:136 B:115 105.0 0.467 E -89.2 131.4 10.0 0.044 0.423 D:p07511:0.422
 HOH
 3.280
 NH2
 O
ARG C:136 C:115 105.0 0.467 E -88.5 131.0 8.0 0.036 0.431 A:p07511:0.431
 HOH
 5.108
 NH1
 O
ARG D:136 D:115 107.0 0.476 E -88.9 129.5 10.0 0.044 0.432 B:p07511:0.431
 HOH
 3.232
 NH2
 O
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:136 A:137 104.0 0.462 E -85.9 137.2 7.0 0.031 0.431 A:P07511:0.431
 HOH
 2.994
 N
 O
ARG B:136 B:137 106.0 0.471 E -86.9 137.5 5.0 0.022 0.449 B:P07511:0.449
 HOH
 2.783
 N
 O
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:136 A:137 104.0 0.462 E -85.9 141.7 9.0 0.04 0.422 A:P07511:0.422
 HOH
 3.128
 NH2
 O
ARG B:136 B:137 105.0 0.467 E -86.4 140.7 6.0 0.027 0.44 B:P07511:0.44
 HOH
 3.077
 NH2
 O
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:136 A:137 107.0 0.476 E -87.0 134.3 9.0 0.04 0.436 A:P07511:0.436
 HOH
 2.971
 N
 O
ARG B:136 B:137 108.0 0.48 E -87.6 133.9 7.0 0.031 0.449 B:P07511:0.449
 HOH
 2.857
 N
 O
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:136 A:137 105.0 0.467 E -92.1 134.2 8.0 0.036 0.431 A:P07511:0.431
 HOH
 2.979
 NH2
 O
ARG B:136 B:137 103.0 0.458 E -93.5 134.5 7.0 0.031 0.427 B:P07511:0.427
 HOH
 2.689
 NH2
 O
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 ARG A:123 A:115 104.0 0.462 E -92.0 142.5 104.0 0.462 0.0 HOH
 9.791
 N
 O
ARG B:123 B:115 107.0 0.476 E -86.3 133.5 107.0 0.476 0.0 HOH
 8.377
 NH2
 O
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 ARG A:131 A:137 109.0 0.484 E -87.6 136.2 14.0 0.062 0.422 C:P50431:0.422
 HOH
 3.054
 NH2
 O
ARG B:131 B:137 108.0 0.48 E -86.4 136.4 12.0 0.053 0.427 D:P50431:0.427
ARG C:131 C:137 107.0 0.476 E -86.5 137.1 15.0 0.067 0.409 A:P50431:0.409
 HOH
 7.906
 CA
 O
ARG D:131 D:137 108.0 0.48 E -87.6 135.8 11.0 0.049 0.431 B:P50431:0.431

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 ARG A:137 A:137 106.0 0.471 E -90.8 129.4