Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18251650 . T A CCDS11196.1:NM_004169.3:c.347cAg>cTg_NP_004160.3:p.116Q>L Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 GLN A:136 A:116 5.0 0.028 -88.6 -27.7 5.0 0.028 0.0 PLP
 8.910
 OE1
 O1P
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 GLN A:106 A:116 5.0 0.028 -89.0 -28.5 5.0 0.028 0.0 PLP
 8.957
 OE1
 O2P
GLN B:106 D:116 3.0 0.017 -87.1 -30.8 3.0 0.017 0.0 PLP
 9.020
 OE1
 O2P
GLN C:106 G:116 4.0 0.022 -92.2 -28.2 4.0 0.022 0.0 PLP
 9.224
 OE1
 O2P
GLN D:106 J:116 4.0 0.022 -93.2 -25.3 4.0 0.022 0.0 PLP
 9.316
 OE1
 O1P
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 GLN A:106 A:116 5.0 0.028 -87.1 -22.6 5.0 0.028 0.0 HOH
 2.885
 O
 O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 GLN A:115 A:94 4.0 0.022 -90.0 -7.8 4.0 0.022 0.0 PLP
HOH
 9.425
2.604
 OE1
OE1
 O3P
O
GLN B:115 B:94 4.0 0.022 -88.5 -12.5 4.0 0.022 0.0 PLP
HOH
 9.430
4.093
 OE1
N
 O2P
O
GLN C:115 C:94 3.0 0.017 -91.2 -8.0 3.0 0.017 0.0 PLP
HOH
 9.505
4.300
 OE1
C
 O2P
O
GLN D:115 D:94 4.0 0.022 -85.7 -14.7 4.0 0.022 0.0 PLP
HOH
 9.451
2.940
 OE1
O
 O2P
O
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 GLN A:115 A:116 4.0 0.022 -100.5 -14.3 4.0 0.022 0.0 PLP
HOH
 9.535
2.741
 OE1
OE1
 O1P
O
GLN B:115 B:116 4.0 0.022 -101.9 -14.1 4.0 0.022 0.0 PLP
HOH
 9.535
2.730
 OE1
OE1
 O1P
O
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 GLN A:115 A:116 3.0 0.017 -93.2 -19.2 3.0 0.017 0.0 PLP
HOH
 9.423
2.683
 OE1
OE1
 O3P
O
GLN B:115 B:116 3.0 0.017 -96.1 -18.4 3.0 0.017 0.0 PLG
HOH
 9.452
2.585
 OE1
OE1
 OP1
O
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 GLN A:115 A:116 4.0 0.022 -91.8 -19.5 4.0 0.022 0.0 PLP
HOH
 9.590
2.674
 O
OE1
 O3P
O
GLN B:115 B:116 4.0 0.022 -92.2 -20.3 4.0 0.022 0.0 PLP
HOH
 9.526
2.686
 OE1
O
 O1P
O
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 GLN A:115 A:116 4.0 0.022 -89.4 -18.3 4.0 0.022 0.0 PLP
HOH
 9.318
2.682
 OE1
O
 O1P
O
GLN B:115 B:116 3.0 0.017 -89.9 -19.6 3.0 0.017 0.0 PLP
HOH
 9.276
2.476
 OE1
O
 O1P
O
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 GLN A:102 A:94 4.0 0.022 -88.5 -20.5 4.0 0.022 0.0 PLP
 9.238
 OE1
 O3P
GLN B:102 B:94 5.0 0.028 -88.9 -10.1 5.0 0.028 0.0 PLP
 9.786
 OE1
 O2P
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 GLN A:110 A:116 5.0 0.028 -96.7 -14.2 5.0 0.028 0.0 PLG
 9.671
 O
 OP1
GLN B:110 B:116 5.0 0.028 -98.2 -13.9 5.0 0.028 0.0 PLG
HOH
 9.716
8.309
 OE1
O
 OP2
O
GLN C:110 C:116 5.0 0.028 -98.4 -13.2 5.0 0.028 0.0 PLG
 9.118
 OE1
 OP2
GLN D:110 D:116 5.0 0.028 -99.2 -12.9 5.0 0.028 0.0 PLG
HOH
 9.493
7.014
 OE1
OE1
 OP2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 GLN A:116 A:116 3.0 0.017 -89.0 -14.1