Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 18257100 . C A CCDS11196.1:NM_004169.3:c.128cGg>cTg_NP_004160.3:p.43R>L Homo sapiens serine hydroxymethyltransferase 1 (SHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6m5w 1 P34896 100.0 0.0 X-RAY
 2021-01-20 ARG A:63 A:43 119.0 0.529 H -52.9 -40.8 44.0 0.196 0.333 A:P34896:0.333
6fl5 1 P34896 99.36 0.0 X-RAY
 2018-10-10 ARG A:33 A:43 114.0 0.507 H -62.8 -45.2 35.0 0.156 0.351 B:P34896:0.351
ARG B:33 D:43 114.0 0.507 H -51.4 -45.2 38.0 0.169 0.338 A:P34896:0.338
ARG C:33 G:43 114.0 0.507 H -53.5 -45.5 38.0 0.169 0.338 D:P34896:0.338
ARG D:33 J:43 115.0 0.511 H -52.5 -44.7 39.0 0.173 0.338 C:P34896:0.338
1bj4 1 P34896 99.36 0.0 X-RAY
 1999-08-16 ARG A:33 A:43 119.0 0.529 H -58.8 -43.2 119.0 0.529 0.0 HOH
 2.520
 O
 O
1ls3 1 p07511 92.92 0.0 X-RAY
 2003-02-04 ARG A:42 A:25 117.0 0.52 H -54.6 -51.1 45.0 0.2 0.32 B:p07511:0.32
 HOH
 2.486
 NH2
 O
ARG B:42 B:25 114.0 0.507 H -56.6 -47.2 39.0 0.173 0.334 A:p07511:0.333
 HOH
 3.275
 NE
 O
ARG C:42 C:25 116.0 0.516 H -57.2 -43.7 46.0 0.204 0.312 D:p07511:0.311
 HOH
 2.716
 O
 O
ARG D:42 D:25 105.0 0.467 H -58.5 -44.6 38.0 0.169 0.298 C:p07511:0.298
 HOH
 3.380
 CD
 O
1rvu 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:42 A:43 120.0 0.533 H -62.0 -44.9 44.0 0.196 0.337 B:P07511:0.338
 HOH
 3.339
 NE
 O
ARG B:42 B:43 115.0 0.511 H -61.9 -45.7 44.0 0.196 0.315 A:P07511:0.316
 HOH
 3.075
 NH1
 O
1rvy 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:42 A:43 123.0 0.547 H -66.3 -47.2 43.0 0.191 0.356 B:P07511:0.356
 HOH
 3.673
 NE
 O
ARG B:42 B:43 122.0 0.542 H -65.8 -48.2 43.0 0.191 0.351 A:P07511:0.351
 HOH
 2.966
 NH1
 O
1rv3 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:42 A:43 120.0 0.533 H -63.4 -37.3 51.0 0.227 0.306 B:P07511:0.307
 HOH
 3.410
 NE
 O
ARG B:42 B:43 115.0 0.511 H -64.6 -37.1 47.0 0.209 0.302 A:P07511:0.302
 HOH
 3.442
 NE
 O
1rv4 1 P07511 92.71 0.0 X-RAY
 2004-06-15 ARG A:42 A:43 116.0 0.516 H -60.3 -40.5 50.0 0.222 0.294 B:P07511:0.293
 HOH
 3.442
 NE
 O
ARG B:42 B:43 117.0 0.52 H -59.2 -41.7 46.0 0.204 0.316 A:P07511:0.316
 HOH
 3.192
 NE
 O
1cj0 1 P07511 93.4 0.0 X-RAY
 1999-05-06 ARG A:29 A:25 110.0 0.489 H -60.9 -22.2 38.0 0.169 0.32 B:P07511:0.32
ARG B:29 B:25 107.0 0.476 H -61.3 -25.9 43.0 0.191 0.285 A:P07511:0.284
1eji 1 P50431 91.19 0.0 X-RAY
 2000-11-03 ARG A:37 A:43 101.0 0.449 H -44.8 -50.7 39.0 0.173 0.276 B:P50431:0.276
ARG B:37 B:43 103.0 0.458 H -43.7 -51.9 43.0 0.191 0.267 A:P50431:0.267
ARG C:37 C:43 108.0 0.48 H -42.9 -53.3 46.0 0.204 0.276 D:P50431:0.276
ARG D:37 D:43 110.0 0.489 H -43.9 -51.0 47.0 0.209 0.28 C:P50431:0.28

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p34896-f1 1 P34896 100.0 0.0 ARG A:43 A:43 94.0 0.418 H -56.5 -46.7