Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr17 | 34416028 | . | A | C | CCDS11307.1:NM_002983.2:c.269cTg>cGg_NP_002974.1:p.90L>R | Homo sapiens C-C motif chemokine ligand 3 (CCL3), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4zkb | 2 | P10147 | 100.0 | 2e-47 |
X-RAY |
2015-07-08 | LEU | B:67 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
2x69 | 1 | P10147 | 100.0 | 2e-47 |
X-RAY |
2010-11-03 | LEU | A:68 | A:68 | 142.0 | 0.835 | T | -74.5 | 48.4 | NA | NA | NA | ||||||
LEU | B:68 | B:68 | 144.0 | 0.847 | T | -90.0 | 46.6 | 144.0 | 0.847 | 0.0 | |||||||||||||
LEU | C:68 | C:68 | 155.0 | 0.912 | H | -62.8 | -20.6 | 155.0 | 0.912 | 0.0 |
HOH |
5.074 |
O |
O |
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LEU | D:68 | D:68 | 151.0 | 0.888 | T | -79.5 | 23.2 | NA | NA | NA | |||||||||||||
LEU | E:68 | E:68 | 141.0 | 0.829 | H | -49.3 | -59.7 | NA | NA | NA | |||||||||||||
3h44 | 2 | P10147 | 100.0 | 2e-47 |
X-RAY |
2010-04-14 | LEU | C:68 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
LEU | D:68 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
5cor | 1 | P10147 | 100.0 | 2e-47 |
X-RAY |
2016-04-13 | LEU | A:68 | A:68 | 144.0 | 0.847 | T | -83.5 | 0.3 | 144.0 | 0.847 | 0.0 |
HOH |
8.342 |
N |
O |
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LEU | B:68 | B:68 | 144.0 | 0.847 | T | -77.0 | -0.6 | NA | NA | NA | |||||||||||||
LEU | C:68 | C:68 | 149.0 | 0.876 | H | -77.0 | -1.1 | 86.0 | 0.506 | 0.37 |
A:P10147:0.371 |
HEZ HOH |
8.227 8.855 |
C CG |
C3 O |
||||||||
LEU | D:68 | D:68 | 147.0 | 0.865 | S | -81.3 | 1.9 | NA | NA | NA | |||||||||||||
LEU | E:68 | E:68 | 143.0 | 0.841 | H | -83.8 | -4.2 | 84.0 | 0.494 | 0.347 |
C:P10147:0.347 |
HOH |
4.015 |
CD1 |
O |
||||||||
LEU | F:68 | F:68 | 147.0 | 0.865 | H | -82.2 | -6.8 | NA | NA | NA | |||||||||||||
LEU | G:68 | G:68 | 144.0 | 0.847 | T | -83.1 | 3.2 | 84.0 | 0.494 | 0.353 |
E:P10147:0.353 |
HOH |
8.247 |
CD2 |
O |
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LEU | H:68 | H:68 | 144.0 | 0.847 | H | -87.6 | -7.5 | NA | NA | NA | |||||||||||||
LEU | I:68 | I:68 | 145.0 | 0.853 | H | -74.8 | -14.4 | 84.0 | 0.494 | 0.359 |
G:P10147:0.359 |
||||||||||||
LEU | J:68 | J:68 | 144.0 | 0.847 | T | -80.7 | 12.0 | NA | NA | NA | |||||||||||||
5d65 | 1 | P10147 | 100.0 | 2e-47 |
X-RAY |
2016-04-20 | LEU | A:68 | A:68 | 143.0 | 0.841 | T | -83.1 | 52.9 | 87.0 | 0.512 | 0.329 |
B:P10147:0.329 |
IDS SGN SGN BGC BGC |
7.773 7.397 8.646 6.507 6.829 |
CD2 CD2 CD2 C CD1 |
O5 O5 O1S O3 O1 |
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LEU | B:68 | B:68 | 136.0 | 0.8 | -96.7 | 65.6 | 79.0 | 0.465 | 0.335 |
E:P10147:0.335 |
IDS SGN SGN |
8.145 7.228 7.013 |
O O O |
O6B O3S O5S |
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LEU | C:68 | C:68 | 140.0 | 0.824 | T | -108.0 | 29.1 | 140.0 | 0.824 | 0.0 |
BGC |
7.278 |
C |
O1 |
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LEU | D:68 | D:68 | 145.0 | 0.853 | -73.3 | 59.2 | 83.0 | 0.488 | 0.365 |
C:P10147:0.365 |
BGC |
7.017 |
CD2 |
O3 |
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LEU | E:68 | E:68 | 150.0 | 0.882 | -76.7 | 64.5 | 150.0 | 0.882 | 0.0 | ||||||||||||||
3kbx | 1 | P10147 | 97.14 | 1e-46 |
X-RAY |
2010-10-27 | LEU | A:68 | A:68 | 138.0 | 0.812 | T | -84.0 | 48.9 | 138.0 | 0.812 | 0.0 | ||||||
LEU | B:68 | B:68 | 138.0 | 0.812 | T | -95.5 | 54.3 | NA | NA | NA | |||||||||||||
LEU | C:68 | C:68 | 146.0 | 0.859 | H | -49.1 | -36.1 | NA | NA | NA | |||||||||||||
LEU | D:68 | D:68 | 137.0 | 0.806 | T | -100.3 | 50.4 | NA | NA | NA | |||||||||||||
LEU | E:68 | E:68 | 120.0 | 0.706 | -65.2 | 109.8 | NA | NA | NA | ||||||||||||||
3fpu | 2 | P10147 | 98.55 | 3e-46 |
X-RAY |
2010-01-12 | LEU | B:68 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
2x6g | 1 | P10147 | 98.57 | 3e-46 |
X-RAY |
2010-11-03 | LEU | A:68 | A:68 | 136.0 | 0.8 | H | -81.0 | -10.4 | NA | NA | NA | ||||||
LEU | B:68 | B:68 | 145.0 | 0.853 | T | -86.6 | 0.7 | NA | NA | NA | |||||||||||||
LEU | C:68 | C:68 | 146.0 | 0.859 | H | -80.4 | -5.8 | NA | NA | NA | |||||||||||||
LEU | D:68 | D:68 | 138.0 | 0.812 | T | -90.5 | 47.4 | NA | NA | NA | |||||||||||||
LEU | E:68 | E:68 | 135.0 | 0.794 | T | -89.3 | 23.5 | NA | NA | NA | |||||||||||||
LEU | F:68 | F:68 | 147.0 | 0.865 | H | -75.2 | -17.5 | NA | NA | NA | |||||||||||||
LEU | G:68 | G:68 | 170.0 | 1.0 | -95.3 | 360.0 | NA | NA | NA | ||||||||||||||
LEU | H:68 | H:68 | 172.0 | 1.0 | -122.4 | 360.0 | NA | NA | NA | ||||||||||||||
LEU | I:68 | I:68 | 140.0 | 0.824 | T | -95.7 | 24.7 | NA | NA | NA | |||||||||||||
LEU | J:68 | J:68 | 140.0 | 0.824 | H | -78.7 | -27.3 | NA | NA | NA | |||||||||||||
LEU | K:68 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
LEU | L:68 | L:68 | 141.0 | 0.829 | T | -66.1 | -1.3 | NA | NA | NA | |||||||||||||
LEU | M:68 | M:68 | 175.0 | 1.0 | -108.6 | 360.0 | NA | NA | NA | ||||||||||||||
LEU | N:68 | N:68 | 144.0 | 0.847 | T | -79.5 | 35.3 | NA | NA | NA | |||||||||||||
LEU | O:68 | O:68 | 158.0 | 0.929 | H | -68.1 | -40.9 | NA | NA | NA | |||||||||||||
LEU | P:68 | P:68 | 131.0 | 0.771 | 52.2 | 38.6 | NA | NA | NA | ||||||||||||||
LEU | Q:68 | Q:68 | 145.0 | 0.853 | T | -85.5 | -2.0 | 145.0 | 0.853 | 0.0 |
HOH |
3.610 |
CD1 |
O |
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LEU | R:68 | R:68 | 179.0 | 1.0 | -83.4 | 360.0 | 179.0 | 1.0 | 0.0 |
HOH |
3.914 |
CB |
O |
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1b50 | 1 | P10147 | 98.55 | 1e-45 |
NMR |
1999-07-22 | LEU | A:67 | A:67 | 130.0 | 0.765 | S | 83.4 | -52.8 | 130.0 | 0.765 | 0.0 | ||||||
LEU | B:67 | B:67 | 128.0 | 0.753 | S | 83.3 | -52.8 | 128.0 | 0.753 | 0.0 | |||||||||||||
1b53 | 1 | P10147 | 98.55 | 1e-45 |
NMR |
1999-07-22 | LEU | A:67 | A:67 | 127.0 | 0.747 | S | 171.4 | 64.1 | 127.0 | 0.747 | 0.0 | ||||||
LEU | B:67 | B:67 | 128.0 | 0.753 | S | 171.4 | 64.1 | 128.0 | 0.753 | 0.0 | |||||||||||||
4ra8 | 1 | P10147 | 98.55 | 1e-45 |
X-RAY |
2014-09-24 | LEU | A:68 | A:68 | 146.0 | 0.859 | T | -95.1 | 28.3 | 146.0 | 0.859 | 0.0 |
HOH |
8.452 |
CD1 |
O |
||
LEU | B:68 | B:68 | 139.0 | 0.818 | T | -101.3 | 34.8 | NA | NA | NA | |||||||||||||
LEU | C:68 | C:68 | 145.0 | 0.853 | H | -78.0 | -6.4 | NA | NA | NA | |||||||||||||
LEU | D:68 | D:68 | 143.0 | 0.841 | T | -108.6 | 28.9 | NA | NA | NA | |||||||||||||
LEU | E:68 | E:68 | 143.0 | 0.841 | H | -69.0 | -32.9 | NA | NA | NA | |||||||||||||
7f1t | 1 | P10147,P51681,P00268 | 98.55 | 3e-43 |
X-RAY |
2021-07-14 | LEU | A:67 | A:-29 | 139.0 | 0.818 | H | -65.1 | -36.7 | 139.0 | 0.818 | 0.0 | ||||||
7f1q | 1 | P10147,P51681 | 98.55 | 8e-43 |
EM |
2021-07-14 | LEU | A:67 | R:67 | 142.0 | 0.835 | H | -65.5 | -32.6 | 142.0 | 0.835 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p10147-f1 | 1 | P10147 | 100.0 | 3e-64 | LEU | A:90 | A:90 | 144.0 | 0.847 | T | -76.3 | -12.4 | |
af-p16619-f1 | 1 | P16619 | 94.62 | 3e-59 | LEU | A:91 | A:91 | 141.0 | 0.829 | T | -75.1 | -13.1 |