Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37824822 . C A CCDS11343.1:NM_002686.4:c.94Ccg>Acg_NP_002677.1:p.32P>T Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1hnn 1 P11086 100.0 0.0 X-RAY
 2001-12-07 PRO A:32 A:32 19.0 0.131 H -51.7 -49.7 19.0 0.131 0.0 SAH
HOH
 7.635
3.288
 CG
CD
 O3'
O
PRO B:32 B:532 19.0 0.131 H -46.2 -54.8 NA NA NA
1n7i 1 P11086 100.0 0.0 X-RAY
 2003-12-23 PRO A:32 A:32 15.0 0.103 H -55.5 -40.4 15.0 0.103 0.0 SAH
HOH
 7.403
6.683
 CG
O
 O3'
O
PRO B:32 B:532 19.0 0.131 H -36.3 -59.2 NA NA NA
1n7j 1 P11086 100.0 0.0 X-RAY
 2003-12-23 PRO A:32 A:32 17.0 0.117 H -45.7 -53.3 17.0 0.117 0.0 SAH
HOH
 7.406
5.907
 CG
O
 O3'
O
PRO B:32 B:532 17.0 0.117 H -41.5 -54.4 NA NA NA
6ws1 1 P11086 100.0 0.0 X-RAY
 2020-08-05 PRO A:44 A:32 17.0 0.117 H -65.6 -41.9 17.0 0.117 0.0 SAH
 7.804
 CB
 O3'
PRO B:44 B:32 28.0 0.193 H -46.5 -66.2 28.0 0.193 0.0 U87
 8.147
 CA
 O3'
1yz3 1 P11086 100.0 0.0 X-RAY
 2006-02-07 PRO A:32 A:32 14.0 0.097 H -51.2 -41.0 14.0 0.097 0.0 SAH
HOH
 7.580
3.180
 CG
CD
 O3'
O
PRO B:32 B:32 17.0 0.117 H -47.0 -57.0 17.0 0.117 0.0 SAH
HOH
 7.835
5.082
 CG
O
 O3'
O
2an3 1 P11086 100.0 0.0 X-RAY
 2006-03-14 PRO A:32 A:32 16.0 0.11 H -51.0 -42.6 16.0 0.11 0.0 SAH
HOH
 7.755
3.549
 CB
CG
 O3'
O
PRO B:32 B:532 16.0 0.11 H -45.8 -56.9 NA NA NA
2an4 1 P11086 100.0 0.0 X-RAY
 2006-03-14 PRO A:32 A:32 14.0 0.097 H -50.5 -45.8 14.0 0.097 0.0 SAH
HOH
 7.198
3.808
 CG
CD
 O3'
O
PRO B:32 B:32 16.0 0.11 H -42.0 -54.7 NA NA NA
2an5 1 P11086 100.0 0.0 X-RAY
 2006-03-14 PRO A:32 A:32 15.0 0.103 H -47.9 -43.8 15.0 0.103 0.0 SAH
TTL
HOH
 7.558
9.897
3.780
 CG
O
CD
 O3'
OAB
O
PRO B:32 B:32 16.0 0.11 H -44.4 -53.5 NA NA NA
2g70 1 P11086 100.0 0.0 X-RAY
 2007-02-13 PRO A:32 A:32 18.0 0.124 H -53.4 -60.1 18.0 0.124 0.0 SAM
HOH
 7.677
7.544
 CG
CB
 O3'
O
PRO B:32 B:32 15.0 0.103 H -39.7 -56.5 NA NA NA
2g71 1 P11086 100.0 0.0 X-RAY
 2007-02-13 PRO A:32 A:32 16.0 0.11 H -45.1 -47.3 16.0 0.11 0.0 SAH
HOH
 7.660
3.407
 CG
CD
 O3'
O
PRO B:32 B:32 16.0 0.11 H -42.0 -56.9 NA NA NA
2g72 1 P11086 100.0 0.0 X-RAY
 2007-02-13 PRO A:32 A:32 15.0 0.103 H -51.5 -49.2 15.0 0.103 0.0 SAM
HOH
 7.662
3.328
 CG
CD
 O3'
O
PRO B:32 B:32 16.0 0.11 H -47.2 -51.5 NA NA NA
2g8n 1 P11086 100.0 0.0 X-RAY
 2006-09-12 PRO A:32 A:32 15.0 0.103 H -48.5 -49.7 15.0 0.103 0.0 SAH
HOH
 7.790
3.352
 CG
CD
 O3'
O
PRO B:32 B:32 15.0 0.103 H -44.2 -55.4 NA NA NA
2ony 1 P11086 100.0 0.0 X-RAY
 2007-10-09 PRO A:32 A:32 16.0 0.11 H -52.3 -53.9 16.0 0.11 0.0 SAH
HOH
 7.538
3.309
 CG
N
 O3'
O
PRO B:32 B:532 17.0 0.117 H -41.0 -56.6 NA NA NA
3hcb 1 P11086 100.0 0.0 X-RAY
 2009-08-25 PRO A:32 A:32 16.0 0.11 H -52.2 -47.1 16.0 0.11 0.0 SAH
 7.662
 CA
 O3'
PRO B:32 B:32 15.0 0.103 H -45.7 -49.9 NA NA NA
3hcc 1 P11086 100.0 0.0 X-RAY
 2009-08-25 PRO A:32 A:32 15.0 0.103 H -48.1 -47.0 15.0 0.103 0.0 SAH
HOH
 7.565
3.871
 CG
N
 O3'
O
PRO B:32 B:32 17.0 0.117 H -48.5 -50.2 NA NA NA
3hcd 1 P11086 100.0 0.0 X-RAY
 2009-08-25 PRO A:32 A:32 14.0 0.097 H -47.1 -48.2 14.0 0.097 0.0 SAH
HOH
 7.432
3.787
 CG
CD
 O3'
O
PRO B:32 B:32 15.0 0.103 H -42.9 -51.6 NA NA NA
3hcf 1 P11086 100.0 0.0 X-RAY
 2009-08-25 PRO A:32 A:32 18.0 0.124 H -55.3 -52.1 18.0 0.124 0.0 SAH
HOH
 7.682
6.071
 CG
O
 O3'
O
PRO B:32 B:32 14.0 0.097 H -44.9 -49.7 NA NA NA
3kpj 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 14.0 0.097 H -55.0 -50.0 14.0 0.097 0.0 SAH
HOH
 7.506
7.673
 CA
CB
 O3'
O
PRO B:32 B:32 17.0 0.117 H -49.8 -53.1 17.0 0.117 0.0 SAH
HOH
 7.754
7.337
 CG
CB
 O3'
O
3kpu 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 16.0 0.11 H -46.8 -46.9 16.0 0.11 0.0 SAH
HOH
 7.847
3.102
 CA
N
 O3'
O
PRO B:32 B:32 17.0 0.117 H -50.7 -48.6 17.0 0.117 0.0 SAH
HOH
 7.809
3.379
 CG
CD
 O3'
O
3kpv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 17.0 0.117 H -51.5 -47.5 17.0 0.117 0.0 SAH
HOH
 7.959
3.303
 CG
CD
 O3'
O
PRO B:32 B:32 17.0 0.117 H -54.6 -45.8 17.0 0.117 0.0 SAH
HOH
 7.856
3.281
 CG
CD
 O3'
O
3kpw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 14.0 0.097 H -46.1 -46.1 14.0 0.097 0.0 SAH
HOH
 7.878
3.683
 CG
N
 O3'
O
PRO B:32 B:32 18.0 0.124 H -52.1 -47.1 18.0 0.124 0.0 SAH
HOH
 7.935
3.227
 CG
CD
 O3'
O
3kpy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 16.0 0.11 H -51.7 -50.1 16.0 0.11 0.0 SAH
HOH
 7.918
3.328
 CA
CD
 O3'
O
PRO B:32 B:32 16.0 0.11 H -54.1 -45.4 16.0 0.11 0.0 SAH
HOH
 7.777
3.288
 CG
CD
 O3'
O
3kqm 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 16.0 0.11 H -45.8 -52.8 16.0 0.11 0.0 SAH
HOH
 7.932
3.519
 CA
N
 O3'
O
PRO B:32 B:32 20.0 0.138 H -51.8 -43.1 20.0 0.138 0.0 SAH
HOH
 7.901
3.332
 CG
CD
 O3'
O
3kqo 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 16.0 0.11 H -52.4 -43.8 16.0 0.11 0.0 SAH
HOH
 7.783
3.327
 CG
CD
 O3'
O
PRO B:32 B:32 15.0 0.103 H -52.7 -43.5 15.0 0.103 0.0 SAH
HOH
 7.841
3.228
 CG
CD
 O3'
O
3kqp 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 17.0 0.117 H -46.5 -53.7 17.0 0.117 0.0 SAH
HOH
 8.022
3.240
 CG
N
 O3'
O
PRO B:32 B:32 15.0 0.103 H -51.0 -46.0 15.0 0.103 0.0 SAH
HOH
 7.781
3.530
 CG
CD
 O3'
O
3kqq 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 15.0 0.103 H -44.1 -52.1 15.0 0.103 0.0 SAH
HOH
 7.878
3.496
 CA
N
 O3'
O
PRO B:32 B:32 17.0 0.117 H -47.2 -46.7 17.0 0.117 0.0 SAH
HOH
 7.999
3.335
 CG
CD
 O3'
O
3kqs 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 16.0 0.11 H -53.5 -44.3 16.0 0.11 0.0 SAH
HOH
 7.837
3.461
 CG
CD
 O3'
O
PRO B:32 B:32 18.0 0.124 H -58.2 -41.8 18.0 0.124 0.0 SAH
HOH
 7.882
3.351
 CG
CD
 O3'
O
3kqt 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 15.0 0.103 H -50.5 -46.6 15.0 0.103 0.0 SAH
HOH
 8.014
3.450
 CG
CD
 O3'
O
PRO B:32 B:32 19.0 0.131 H -51.4 -44.4 19.0 0.131 0.0 SAH
HOH
 7.914
3.276
 CG
CD
 O3'
O
3kqv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 15.0 0.103 H -48.6 -45.1 15.0 0.103 0.0 SAH
HOH
 7.764
3.593
 CG
N
 O3'
O
PRO B:32 B:32 20.0 0.138 H -53.8 -45.1 20.0 0.138 0.0 SAH
HOH
 7.784
3.311
 CG
CD
 O3'
O
3kqw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 16.0 0.11 H -52.9 -41.9 16.0 0.11 0.0 SAH
HOH
 7.836
3.404
 CG
CD
 O3'
O
PRO B:32 B:32 19.0 0.131 H -57.0 -42.8 19.0 0.131 0.0 SAH
HOH
 7.690
3.235
 CG
CD
 O3'
O
3kqy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 16.0 0.11 H -53.7 -45.7 16.0 0.11 0.0 SAH
HOH
 7.768
3.567
 CG
N
 O3'
O
PRO B:32 B:32 18.0 0.124 H -50.9 -48.3 18.0 0.124 0.0 SAH
ES0
HOH
 7.870
9.769
3.239
 CG
O
CD
 O3'
NAA
O
3kr0 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 15.0 0.103 H -58.2 -44.2 15.0 0.103 0.0 SAH
HOH
 7.687
3.355
 CG
CD
 O3'
O
PRO B:32 B:32 18.0 0.124 H -54.2 -46.1 18.0 0.124 0.0 SAH
HOH
 7.614
3.317
 CG
CD
 O3'
O
3kr1 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 16.0 0.11 H -51.8 -46.5 16.0 0.11 0.0 SAH
HOH
 7.722
3.424
 CG
CD
 O3'
O
PRO B:32 B:32 17.0 0.117 H -57.3 -46.5 17.0 0.117 0.0 SAH
HOH
 7.735
3.305
 CG
CD
 O3'
O
3kr2 1 P11086 100.0 0.0 X-RAY
 2010-09-29 PRO A:32 A:32 15.0 0.103 H -48.4 -46.5 15.0 0.103 0.0 SAH
HOH
 7.641
3.477
 CG
N
 O3'
O
PRO B:32 B:32 16.0 0.11 H -52.4 -46.3 16.0 0.11 0.0 SAH
HOH
 7.828
3.326
 CG
CD
 O3'
O
4dm3 1 P11086 100.0 0.0 X-RAY
 2012-04-25 PRO A:32 A:32 16.0 0.11 H -47.9 -52.1 16.0 0.11 0.0 SAH
HOH
 7.974
4.235
 CG
CD
 O3'
O
PRO B:32 B:32 17.0 0.117 H -53.1 -49.0 17.0 0.117 0.0 SAH
HOH
 7.844
3.231
 CG
CD
 O3'
O
4mik 1 P11086 100.0 0.0 X-RAY
 2014-09-10 PRO A:32 A:32 16.0 0.11 H -48.9 -42.1 16.0 0.11 0.0 JIL
TRS
HOH
 6.060
7.193
2.821
 HG3
HA
HD2
 H011
H21
O
PRO B:32 B:32 17.0 0.117 H -53.7 -43.7 17.0 0.117 0.0 JIL
TRS
HOH
 6.180
7.412
2.503
 HG3
HA
HD2
 H011
H31
O
4mq4 1 P11086 100.0 0.0 X-RAY
 2014-10-15 PRO A:32 A:32 15.0 0.103 H -44.5 -51.8 15.0 0.103 0.0 2D5
TRS
HOH
 7.095
7.487
2.529
 HG3
HA
HD2
 O15
H32
O
PRO B:32 B:32 16.0 0.11 H -46.2 -47.3 16.0 0.11 0.0 2D5
TRS
HOH
 6.621
7.080
2.661
 HG3
HA
HD2
 H171
H12
O
3hca 1 P11086 99.65 0.0 X-RAY
 2009-08-25 PRO A:32 A:32 15.0 0.103 H -48.5 -50.4 15.0 0.103 0.0 SAH
HOH
 7.602
3.423
 CG
CD
 O3'
O
PRO B:32 B:32 17.0 0.117 H -48.7 -53.7 NA NA NA
3hce 1 P11086 99.65 0.0 X-RAY
 2009-08-25 PRO A:32 A:32 16.0 0.11 H -56.8 -37.7 16.0 0.11 0.0 SAH
HOH
 7.594
6.463
 CG
O
 O3'
O
PRO B:32 B:32 17.0 0.117 H -53.3 -38.2 NA NA NA
2obf 1 P11086 99.65 0.0 X-RAY
 2007-10-09 PRO A:32 A:32 14.0 0.097 H -50.6 -43.9 14.0 0.097 0.0 SAH
HOH
 7.612
3.575
 CG
CD
 O3'
O
PRO B:32 B:532 16.0 0.11 H -41.8 -50.0 NA NA NA
2onz 1 P11086 99.65 0.0 X-RAY
 2007-10-09 PRO A:32 A:32 16.0 0.11 H -40.2 -47.5 16.0 0.11 0.0 SAH
HOH
 7.622
3.400
 CG
CD
 O3'
O
PRO B:32 B:532 19.0 0.131 H -41.5 -48.4 NA NA NA
2opb 1 P11086 99.65 0.0 X-RAY
 2007-10-09 PRO A:32 A:32 15.0 0.103 H -42.0 -46.8 15.0 0.103 0.0 SAH
HOH
 7.437
6.308
 CG
CD
 O3'
O
PRO B:32 B:32 16.0 0.11 H -34.3 -51.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11086-f1 1 P11086 100.0 0.0 PRO A:32 A:32 17.0 0.117 H -57.1 -42.7