Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr17 | 37825908 | . | G | A | CCDS11343.1:NM_002686.4:c.229Gac>Aac_NP_002677.1:p.77D>N | Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1hnn | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2001-12-07 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -100.7 | 122.4 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.493 6.419 |
OD2 N |
N O |
||
| ASP | B:77 | B:577 | 0.0 | 0.0 | E | -100.3 | 120.0 | NA | NA | NA | |||||||||||||
| 1n7i | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2003-12-23 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -109.8 | 108.9 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.747 8.052 |
OD1 OD1 |
N O |
||
| ASP | B:77 | B:577 | 0.0 | 0.0 | E | -103.0 | 107.5 | NA | NA | NA | |||||||||||||
| 1n7j | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2003-12-23 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -103.6 | 113.9 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.442 8.144 |
OD1 OD1 |
N O |
||
| ASP | B:77 | B:577 | 0.0 | 0.0 | E | -101.4 | 107.8 | NA | NA | NA | |||||||||||||
| 6ws1 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2020-08-05 | ASP | A:89 | A:77 | 0.0 | 0.0 | E | -107.9 | 114.6 | 0.0 | 0.0 | 0.0 |
SAH |
5.487 |
OD2 |
N |
||
| ASP | B:89 | B:77 | 0.0 | 0.0 | E | -91.0 | 127.1 | 0.0 | 0.0 | 0.0 |
U87 |
5.993 |
OD2 |
N |
|||||||||
| 1yz3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-02-07 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -107.6 | 107.9 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.575 2.938 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -93.2 | 118.4 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.563 2.867 |
OD2 OD1 |
N O |
|||||||||
| 2an3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -104.8 | 113.8 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.349 6.501 |
OD2 N |
N O |
||
| ASP | B:77 | B:577 | 0.0 | 0.0 | E | -103.6 | 109.1 | NA | NA | NA | |||||||||||||
| 2an4 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -106.3 | 117.1 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.557 2.783 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -101.1 | 115.2 | NA | NA | NA | |||||||||||||
| 2an5 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -105.0 | 110.7 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.499 6.574 |
OD2 N |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -99.7 | 113.8 | NA | NA | NA | |||||||||||||
| 2g70 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -101.4 | 112.4 | 0.0 | 0.0 | 0.0 |
SAM |
5.743 |
OD2 |
N |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -103.2 | 111.2 | NA | NA | NA | |||||||||||||
| 2g71 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -102.1 | 114.1 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.461 2.865 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -100.0 | 119.9 | NA | NA | NA | |||||||||||||
| 2g72 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -103.5 | 114.4 | 0.0 | 0.0 | 0.0 |
SAM HOH |
5.484 2.751 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -100.0 | 121.5 | NA | NA | NA | |||||||||||||
| 2g8n | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-09-12 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -101.6 | 116.1 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.528 2.895 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -97.3 | 119.6 | NA | NA | NA | |||||||||||||
| 2ony | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-10-09 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -102.9 | 112.2 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.488 8.012 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:577 | 0.0 | 0.0 | E | -100.0 | 114.7 | NA | NA | NA | |||||||||||||
| 3hcb | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -102.7 | 118.5 | 0.0 | 0.0 | 0.0 |
SAH |
5.497 |
OD2 |
N |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -100.0 | 122.0 | NA | NA | NA | |||||||||||||
| 3hcc | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -102.6 | 117.2 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.562 2.887 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -99.5 | 116.5 | NA | NA | NA | |||||||||||||
| 3hcd | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -101.4 | 112.2 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.506 2.950 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -96.8 | 120.7 | NA | NA | NA | |||||||||||||
| 3hcf | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -95.6 | 120.1 | 0.0 | 0.0 | 0.0 |
SAH EDO |
5.408 7.452 |
OD2 OD1 |
N O1 |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -98.1 | 118.0 | NA | NA | NA | |||||||||||||
| 3kpj | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -95.2 | 109.1 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.479 7.774 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -90.8 | 123.3 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.559 7.953 |
OD2 OD1 |
N O |
|||||||||
| 3kpu | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -99.7 | 119.5 | 0.0 | 0.0 | 0.0 |
SAH |
5.159 |
OD2 |
N |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -98.6 | 123.3 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.415 2.928 |
OD2 OD1 |
N O |
|||||||||
| 3kpv | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -93.4 | 123.1 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.100 7.215 |
OD2 N |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -93.5 | 120.5 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.259 2.712 |
OD2 OD1 |
N O |
|||||||||
| 3kpw | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -100.5 | 118.8 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.102 6.732 |
OD2 N |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -100.8 | 123.0 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.235 2.757 |
OD2 OD1 |
N O |
|||||||||
| 3kpy | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -101.4 | 118.8 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.136 6.794 |
OD2 N |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -97.5 | 121.9 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.300 2.790 |
OD2 OD1 |
N O |
|||||||||
| 3kqm | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -100.4 | 119.8 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.317 8.516 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -96.1 | 121.0 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.420 2.851 |
OD2 OD1 |
N O |
|||||||||
| 3kqo | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -100.8 | 122.6 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.268 6.645 |
OD2 N |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -96.0 | 123.1 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.472 2.909 |
OD2 OD1 |
N O |
|||||||||
| 3kqp | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -95.2 | 120.2 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.054 7.627 |
OD2 N |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -95.7 | 120.3 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.407 2.961 |
OD2 OD1 |
N O |
|||||||||
| 3kqq | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -102.4 | 111.3 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.328 7.141 |
OD2 N |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -98.9 | 120.4 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.306 2.786 |
OD2 OD1 |
N O |
|||||||||
| 3kqs | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -95.9 | 121.8 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.376 6.649 |
OD2 N |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -92.8 | 120.5 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.412 2.791 |
OD2 OD1 |
N O |
|||||||||
| 3kqt | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -96.3 | 123.5 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.256 6.518 |
OD2 N |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -90.7 | 126.8 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.421 2.952 |
OD2 OD1 |
N O |
|||||||||
| 3kqv | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -95.9 | 121.9 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.532 6.716 |
OD2 N |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -93.5 | 122.1 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.332 2.823 |
OD2 OD1 |
N O |
|||||||||
| 3kqw | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -102.6 | 120.7 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.078 8.333 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -94.5 | 125.0 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.438 3.038 |
OD2 OD1 |
N O |
|||||||||
| 3kqy | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -99.6 | 116.2 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.355 2.811 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -98.4 | 118.4 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.344 2.839 |
OD2 OD1 |
N O |
|||||||||
| 3kr0 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -103.2 | 118.6 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.449 7.878 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -102.8 | 120.6 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.292 6.263 |
OD2 N |
N O |
|||||||||
| 3kr1 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -96.9 | 117.9 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.449 2.699 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -94.6 | 118.1 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.477 3.006 |
OD2 OD1 |
N O |
|||||||||
| 3kr2 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -98.5 | 118.7 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.451 2.773 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -93.1 | 121.0 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.371 2.854 |
OD2 OD1 |
N O |
|||||||||
| 4dm3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2012-04-25 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -100.5 | 115.7 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.292 2.804 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -97.1 | 120.2 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.367 2.830 |
OD2 OD1 |
N O |
|||||||||
| 4mik | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2014-09-10 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -97.8 | 119.0 | 0.0 | 0.0 | 0.0 |
JIL TRS HOH |
7.605 4.276 2.731 |
O OD1 OD1 |
H341 HO1 O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -95.9 | 119.9 | 0.0 | 0.0 | 0.0 |
JIL TRS HOH |
7.530 4.356 2.850 |
O OD1 OD1 |
H341 HO2 O |
|||||||||
| 4mq4 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2014-10-15 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -93.2 | 120.5 | 0.0 | 0.0 | 0.0 |
2D5 TRS HOH |
7.533 4.681 2.931 |
O OD2 OD1 |
H041 O2 O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -103.8 | 115.2 | 0.0 | 0.0 | 0.0 |
2D5 TRS HOH |
7.702 5.009 2.757 |
O OD2 OD1 |
H041 H32 O |
|||||||||
| 3hca | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2009-08-25 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -99.4 | 115.6 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.514 2.803 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -93.8 | 121.4 | NA | NA | NA | |||||||||||||
| 3hce | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2009-08-25 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -103.7 | 120.9 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.503 7.600 |
OD1 OD1 |
N O |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -92.6 | 125.1 | NA | NA | NA | |||||||||||||
| 2obf | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -101.6 | 115.3 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.629 2.916 |
OD2 OD1 |
N O |
||
| ASP | B:77 | B:577 | 0.0 | 0.0 | E | -96.1 | 118.7 | NA | NA | NA | |||||||||||||
| 2onz | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -104.4 | 110.0 | 0.0 | 0.0 | 0.0 |
SAH HOH |
5.723 6.665 |
OD2 N |
N O |
||
| ASP | B:77 | B:577 | 0.0 | 0.0 | E | -92.0 | 118.3 | NA | NA | NA | |||||||||||||
| 2opb | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -102.9 | 113.2 | 0.0 | 0.0 | 0.0 |
SAH |
5.771 |
OD1 |
N |
||
| ASP | B:77 | B:77 | 0.0 | 0.0 | E | -98.2 | 116.0 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p11086-f1 | 1 | P11086 | 100.0 | 0.0 | ASP | A:77 | A:77 | 0.0 | 0.0 | E | -91.0 | 109.7 | |