Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37825929 . G A CCDS11343.1:NM_002686.4:c.250Gtg>Atg_NP_002677.1:p.84V>M Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1hnn 1 P11086 100.0 0.0 X-RAY
 2001-12-07 VAL A:84 A:84 0.0 0.0 -128.9 -6.4 0.0 0.0 0.0 SAH
HOH
 6.611
5.024
 N
CG1
 O
O
VAL B:84 B:584 0.0 0.0 -132.1 -18.0 NA NA NA
1n7i 1 P11086 100.0 0.0 X-RAY
 2003-12-23 VAL A:84 A:84 0.0 0.0 -121.1 -24.2 0.0 0.0 0.0 SAH
HOH
 6.616
5.914
 N
O
 C
O
VAL B:84 B:584 1.0 0.006 -124.5 -44.4 NA NA NA
1n7j 1 P11086 100.0 0.0 X-RAY
 2003-12-23 VAL A:84 A:84 1.0 0.006 -123.3 -14.6 1.0 0.006 0.0 SAH
HOH
 6.806
5.947
 N
O
 OXT
O
VAL B:84 B:584 0.0 0.0 -130.7 -29.0 NA NA NA
6ws1 1 P11086 100.0 0.0 X-RAY
 2020-08-05 VAL A:96 A:84 3.0 0.019 -138.7 -11.4 3.0 0.019 0.0 SAH
 6.545
 N
 OXT
VAL B:96 B:84 3.0 0.019 -143.0 -22.7 3.0 0.019 0.0 U87
HOH
 6.630
8.788
 N
CG2
 O1
O
1yz3 1 P11086 100.0 0.0 X-RAY
 2006-02-07 VAL A:84 A:84 0.0 0.0 -123.5 -13.7 0.0 0.0 0.0 SAH
HOH
 6.894
4.782
 N
CG1
 CA
O
VAL B:84 B:84 1.0 0.006 -128.0 -13.1 1.0 0.006 0.0 SAH
HOH
 6.870
4.786
 N
CG1
 CA
O
2an3 1 P11086 100.0 0.0 X-RAY
 2006-03-14 VAL A:84 A:84 0.0 0.0 -127.0 -7.9 0.0 0.0 0.0 SAH
HOH
 6.683
4.909
 N
CG1
 CA
O
VAL B:84 B:584 0.0 0.0 -131.5 -11.4 NA NA NA
2an4 1 P11086 100.0 0.0 X-RAY
 2006-03-14 VAL A:84 A:84 0.0 0.0 -119.5 -14.4 0.0 0.0 0.0 SAH
HOH
 6.729
5.786
 N
O
 CA
O
VAL B:84 B:84 1.0 0.006 -125.9 -15.8 NA NA NA
2an5 1 P11086 100.0 0.0 X-RAY
 2006-03-14 VAL A:84 A:84 1.0 0.006 -130.0 -10.0 1.0 0.006 0.0 SAH
HOH
 6.842
5.779
 N
O
 CA
O
VAL B:84 B:84 0.0 0.0 -128.0 -19.9 NA NA NA
2g70 1 P11086 100.0 0.0 X-RAY
 2007-02-13 VAL A:84 A:84 1.0 0.006 -125.1 -21.8 1.0 0.006 0.0 SAM
HOH
 6.700
7.133
 N
CG1
 CA
O
VAL B:84 B:84 1.0 0.006 -127.3 -23.6 NA NA NA
2g71 1 P11086 100.0 0.0 X-RAY
 2007-02-13 VAL A:84 A:84 0.0 0.0 -128.7 -10.3 0.0 0.0 0.0 SAH
FTS
HOH
 6.927
9.217
5.126
 N
N
CG1
 CA
F2
O
VAL B:84 B:84 1.0 0.006 -125.7 -7.5 NA NA NA
2g72 1 P11086 100.0 0.0 X-RAY
 2007-02-13 VAL A:84 A:84 0.0 0.0 -128.5 -7.3 0.0 0.0 0.0 SAM
F21
HOH
 6.925
9.285
4.961
 N
C
CG1
 CA
S2
O
VAL B:84 B:84 1.0 0.006 -127.6 -4.1 NA NA NA
2g8n 1 P11086 100.0 0.0 X-RAY
 2006-09-12 VAL A:84 A:84 0.0 0.0 -128.6 -6.8 0.0 0.0 0.0 F83
SAH
HOH
 8.102
6.927
4.775
 C
N
CG1
 CL1
CA
O
VAL B:84 B:84 1.0 0.006 -129.7 -8.6 NA NA NA
2ony 1 P11086 100.0 0.0 X-RAY
 2007-10-09 VAL A:84 A:84 1.0 0.006 -122.7 -17.8 1.0 0.006 0.0 SAH
TMJ
HOH
 6.931
8.368
4.892
 N
C
CG1
 OXT
CL1
O
VAL B:84 B:584 1.0 0.006 -133.9 -14.7 NA NA NA
3hcb 1 P11086 100.0 0.0 X-RAY
 2009-08-25 VAL A:84 A:84 1.0 0.006 -124.7 -10.2 1.0 0.006 0.0 SAH
 6.794
 N
 CA
VAL B:84 B:84 1.0 0.006 -126.7 -8.3 NA NA NA
3hcc 1 P11086 100.0 0.0 X-RAY
 2009-08-25 VAL A:84 A:84 1.0 0.006 -127.3 -11.2 1.0 0.006 0.0 SAH
HOH
 6.680
4.551
 N
CG1
 CA
O
VAL B:84 B:84 1.0 0.006 -129.7 -16.4 NA NA NA
3hcd 1 P11086 100.0 0.0 X-RAY
 2009-08-25 VAL A:84 A:84 0.0 0.0 -115.7 -17.1 0.0 0.0 0.0 SAH
HOH
 6.637
4.869
 N
CG1
 CA
O
VAL B:84 B:84 1.0 0.006 -127.2 -19.2 NA NA NA
3hcf 1 P11086 100.0 0.0 X-RAY
 2009-08-25 VAL A:84 A:84 1.0 0.006 -125.5 -23.3 1.0 0.006 0.0 SAH
HOH
 6.715
6.968
 N
CG2
 CA
O
VAL B:84 B:84 0.0 0.0 -127.2 -20.5 NA NA NA
3kpj 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 1.0 0.006 -120.7 -18.1 1.0 0.006 0.0 SAH
HOH
 6.754
6.589
 N
CG2
 CA
O
VAL B:84 B:84 1.0 0.006 -121.3 -19.4 1.0 0.006 0.0 SAH
HOH
 6.858
5.963
 N
CG2
 CA
O
3kpu 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 0.0 0.0 -123.9 -14.8 0.0 0.0 0.0 SAH
HOH
 6.776
7.022
 N
CG1
 C
O
VAL B:84 B:84 3.0 0.019 -129.2 -6.1 3.0 0.019 0.0 SAH
HOH
 6.757
4.902
 N
CG1
 CA
O
3kpv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 1.0 0.006 -120.8 -9.9 1.0 0.006 0.0 SAH
HOH
 6.851
4.876
 N
CG1
 C
O
VAL B:84 B:84 1.0 0.006 -129.2 -10.8 1.0 0.006 0.0 SAH
HOH
 6.754
4.805
 N
CG1
 CA
O
3kpw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 0.0 0.0 -118.0 -10.8 0.0 0.0 0.0 SAH
HOH
 6.876
5.878
 N
O
 C
O
VAL B:84 B:84 2.0 0.013 -127.6 -9.2 2.0 0.013 0.0 SAH
HOH
 6.691
4.927
 N
CG1
 CA
O
3kpy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 1.0 0.006 -121.4 -15.7 1.0 0.006 0.0 SAH
HOH
 6.790
5.827
 N
O
 C
O
VAL B:84 B:84 2.0 0.013 -125.8 -12.2 2.0 0.013 0.0 SAH
HOH
 6.689
4.724
 N
CG1
 CA
O
3kqm 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 0.0 0.0 -120.3 -6.6 0.0 0.0 0.0 SAH
HOH
 6.860
4.837
 N
CG1
 C
O
VAL B:84 B:84 2.0 0.013 -125.4 -15.4 2.0 0.013 0.0 SAH
HOH
 6.802
5.514
 N
O
 CA
O
3kqo 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 1.0 0.006 -124.3 -10.6 1.0 0.006 0.0 SAH
HOH
 6.835
5.902
 N
O
 C
O
VAL B:84 B:84 0.0 0.0 -126.9 -12.2 0.0 0.0 0.0 SAH
HOH
 6.673
4.980
 N
CG1
 CA
O
3kqp 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 0.0 0.0 -117.9 -15.9 0.0 0.0 0.0 SAH
 6.763
 N
 C
VAL B:84 B:84 1.0 0.006 -128.0 -9.2 1.0 0.006 0.0 SAH
HOH
 6.783
4.797
 N
CG1
 CA
O
3kqq 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 1.0 0.006 -125.6 -9.2 1.0 0.006 0.0 SAH
HOH
 6.736
6.976
 N
CG1
 C
O
VAL B:84 B:84 2.0 0.013 -124.5 -10.9 2.0 0.013 0.0 SAH
HOH
 6.769
4.671
 N
CG1
 CA
O
3kqs 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 0.0 0.0 -127.3 -8.6 0.0 0.0 0.0 SAH
HOH
 6.824
4.904
 N
CG1
 CA
O
VAL B:84 B:84 1.0 0.006 -126.1 -7.3 1.0 0.006 0.0 SAH
HOH
 6.853
4.871
 N
CG1
 CA
O
3kqt 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 1.0 0.006 -125.4 -6.4 1.0 0.006 0.0 SAH
HOH
 6.837
4.737
 N
CG1
 CA
O
VAL B:84 B:84 1.0 0.006 -130.4 -10.4 1.0 0.006 0.0 SAH
HOH
 6.733
4.585
 N
CG1
 CA
O
3kqv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 0.0 0.0 -125.9 -7.6 0.0 0.0 0.0 SAH
HOH
 6.810
4.893
 N
CG1
 CA
O
VAL B:84 B:84 1.0 0.006 -126.6 -9.0 1.0 0.006 0.0 SAH
HOH
 6.799
4.796
 N
CG1
 CA
O
3kqw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 0.0 0.0 -122.6 -18.1 0.0 0.0 0.0 SAH
HOH
 6.806
5.915
 N
O
 C
O
VAL B:84 B:84 0.0 0.0 -125.9 -14.0 0.0 0.0 0.0 SAH
HOH
 6.609
5.598
 N
O
 CA
O
3kqy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 0.0 0.0 -130.8 -16.0 0.0 0.0 0.0 SAH
HOH
 6.750
4.854
 N
CG1
 CA
O
VAL B:84 B:84 1.0 0.006 -133.6 -11.3 1.0 0.006 0.0 SAH
HOH
 6.611
4.908
 N
CG1
 C
O
3kr0 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 1.0 0.006 -130.6 -16.3 1.0 0.006 0.0 SAH
HOH
 6.697
5.414
 N
O
 CA
O
VAL B:84 B:84 3.0 0.019 -129.5 -16.6 3.0 0.019 0.0 SAH
HOH
 6.628
6.976
 N
CG1
 CA
O
3kr1 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 1.0 0.006 -129.2 -6.9 1.0 0.006 0.0 SAH
HOH
 6.739
4.691
 N
CG1
 CA
O
VAL B:84 B:84 1.0 0.006 -127.6 -11.2 1.0 0.006 0.0 SAH
HOH
 6.686
4.754
 N
CG1
 CA
O
3kr2 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:84 A:84 0.0 0.0 -124.9 -9.9 0.0 0.0 0.0 SAH
HOH
 6.792
5.113
 N
CG1
 CA
O
VAL B:84 B:84 0.0 0.0 -129.3 -9.2 0.0 0.0 0.0 SAH
HOH
 6.668
5.719
 N
O
 CA
O
4dm3 1 P11086 100.0 0.0 X-RAY
 2012-04-25 VAL A:84 A:84 1.0 0.006 -119.9 -13.1 1.0 0.006 0.0 SAH
HOH
 6.931
4.966
 N
CG1
 C
O
VAL B:84 B:84 1.0 0.006 -128.2 -11.8 1.0 0.006 0.0 SAH
HOH
 6.693
4.647
 N
CG1
 C
O
4mik 1 P11086 100.0 0.0 X-RAY
 2014-09-10 VAL A:84 A:84 0.0 0.0 -124.8 -6.4 0.0 0.0 0.0 TRS
HOH
 5.806
3.942
 N
HG13
 H22
O
VAL B:84 B:84 1.0 0.006 -128.3 -5.4 1.0 0.006 0.0 JIL
TRS
HOH
 9.963
5.491
3.927
 H
N
HG13
 H221
H32
O
4mq4 1 P11086 100.0 0.0 X-RAY
 2014-10-15 VAL A:84 A:84 0.0 0.0 -136.8 -20.4 0.0 0.0 0.0 2D5
TRS
HOH
 9.789
5.514
5.416
 N
N
CB
 H272
H21
O
VAL B:84 B:84 0.0 0.0 -123.7 -12.1 0.0 0.0 0.0 2D5
TRS
HOH
 9.762
5.823
4.200
 H
N
HG13
 H311
H11
O
3hca 1 P11086 99.65 0.0 X-RAY
 2009-08-25 VAL A:84 A:84 0.0 0.0 -130.2 -7.9 0.0 0.0 0.0 SAH
HOH
 6.720
5.048
 N
CG1
 CA
O
VAL B:84 B:84 2.0 0.013 -129.6 -10.7 NA NA NA
3hce 1 P11086 99.65 0.0 X-RAY
 2009-08-25 VAL A:84 A:84 1.0 0.006 -120.3 -12.7 1.0 0.006 0.0 SAH
HOH
 6.827
6.892
 N
CG1
 CA
O
VAL B:84 B:84 3.0 0.019 -121.1 -22.1 NA NA NA
2obf 1 P11086 99.65 0.0 X-RAY
 2007-10-09 VAL A:84 A:84 0.0 0.0 -129.6 -14.7 0.0 0.0 0.0 F83
SAH
HOH
 8.059
6.953
4.816
 C
N
CG1
 CL1
C
O
VAL B:84 B:584 1.0 0.006 -131.3 -10.6 NA NA NA
2onz 1 P11086 99.65 0.0 X-RAY
 2007-10-09 VAL A:84 A:84 1.0 0.006 -136.8 -22.2 1.0 0.006 0.0 SAH
TMJ
HOH
 6.748
8.163
5.529
 N
C
CG1
 OXT
CL1
O
VAL B:84 B:584 1.0 0.006 -132.6 -10.5 NA NA NA
2opb 1 P11086 99.65 0.0 X-RAY
 2007-10-09 VAL A:84 A:84 2.0 0.013 -122.7 -18.8 2.0 0.013 0.0 F21
SAH
HOH
 8.854
6.755
8.769
 C
N
CG2
 S2
OXT
O
VAL B:84 B:84 1.0 0.006 -130.8 -13.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11086-f1 1 P11086 100.0 0.0 VAL A:84 A:84 0.0 0.0 -127.0 -8.1